1,25-Dihydroxyvitamin D3 modulates adipogenesis of human adipose-derived mesenchymal stem cells dose-dependently

Nutrition & Metabolism

Table 2 Comparison of protein expression in 1,25-Dihydroxyvitamin D3 groups vs. control

Proteins	Time	Group	Mean§	Standard Deviation	Result
FABP4	Day 6	Control	0.27	0.03	X = 8.76 df = 2 P value = 0.012*
		10⁻⁸MVitD	0.17	0.007
		10⁻¹⁰ M VitD	0.14	0.03
	Day 14	Control	0.32	0.02	X = 7. 26 df = 2 P value = 0.026*
		10⁻⁸ M VitD	0.20	0.04
		10⁻¹⁰ M VitD	0.24	0.05
GLUT4	Day 6	Control	0.17	0.03	X = 8.76 df = 2 P value = 0.012*
		10⁻⁸ M VitD	0.12	0.02
		10⁻¹⁰ M VitD	0.08	0.02
	Day 14	Control	0.20	0.01	X = 7. 26 df = 2 P value = 0.026*
		10⁻⁸ M VitD	0.20	0.03
		10⁻¹⁰ M VitD	0.15	0.03
VDR	Day 6	Control	0.69	0.45	X = 4.19 df = 2 P value = 0.012*
		10⁻⁸ M VitD	0.44	0.02
		10⁻¹⁰ M VitD	0.35	0.08
	Day 14	Control	0.80	0.05	X = 7. 26 df = 2 P value = 0.026*
		10⁻⁸ M VitD	0.50	0.09
		10⁻¹⁰ M VitD	0.60	0.13

FABP4: Fatty acid binding proteins-4; GLUT4: Glucose transporter-4; VDR: Vitamin D receptor § ng/mg total protein
^*Mean values were significantly different between the groups (P < 0.05)

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