Combined effect of vitamin C and vitamin D3 on intestinal epithelial barrier by regulating Notch signaling pathway

Table 5 Effect of VC + VD₃ on DSS-induced colonic morphology in guinea pigs (\(\overline{x }\) ± s, n = 6)

Group	Length of colon (cm)	Colonic gross morphological score	Colonic histopathological score
Control	60.80 ± 12.73	0.00 ± 0.00	0.00 ± 0.00
LVC + VD₃ + DSS	60.90 ± 10.76	2.80 ± 0.83^a	3.50 ± 0.55^a
MVC + VD₃ + DSS	52.00 ± 7.77	2.00 ± 0.63^a	4.00 ± 0.71^a
HVC + VD₃ + DSS	64.70 ± 5.25^b	2.50 ± 0.57^a	3.50 ± 0.84^a
P value	0.148	0.000	0.000

^aP indicates compared with the control group, P < 0.05; the ^bP expression compared with the MVC group, P < 0.05

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