PS-341 alleviates chronic low-grade inflammation and improves insulin sensitivity through the inhibition of TM4 (UBAC2) degradation

Table 1 Association of TM4 SNP rs147851454 with obesity

NGT Obesity	CC/CT/TT		C allele frequency		Risk allele (T)		Genotype (unadjusted)		Adjusted with age and gender
NGT Obesity	Over weight	Normal	Cases	Controls	OR (95% CI)	P	OR (95%CI)	P	OR (95%CI)	P
HRM	981/37/1	2320/53/2	0.981	0.988	1.6063 (1.0653,2.4220)	0.0225	1.571 (1.051,2.347)	0.0275	1.547 (1.032,2.319)	0.0347

ISSN: 1743-7075