Fig. 3From: Estradiol regulates intestinal ABCG2 to promote urate excretion via the PI3K/Akt pathwaya1 Renal ABCG2 immunohistochemistry staining of control mice, Grade 1. a2 Renal ABCG2 immunohistochemistry staining of hyperuricemic mice, Grade 1. a3–a5 Renal ABCG2 immunohistochemistry staining of EB (0.2 mg/kg, 1 mg/kg, and 5 mg/kg) intervention in hyperuricemic mice, Grade 1, Grade 1, Grade 1. b1 Intestinal ABCG2 immunohistochemistry staining of control mice, Grade 1. b2 Intestinal ABCG2 immunohistochemistry staining of hyperuricemia mice, Grade 2. b3–b5 Intestinal ABCG2 immunohistochemistry staining of EB (0.2 mg/kg, 1 mg/kg, and 5 mg/kg) intervention hyperuricemia mice, Grade 3, Grade 3, and Grade 3Back to article page