Skip to main content
Fig. 7 | Nutrition & Metabolism

Fig. 7

From: Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect

Fig. 7

Schematic diagram showing the proposed mechanism of the preventive effect of DHM against liver fibrosis via inhibiting HSCs activation by inducing autophagy and enhanced NK cells killing effect to HSCs through the AhR-NF-κB/STAT3- IFN-γ pathways. DHM attenuated CCl4-induced liver injury and fibrosis in vivo. On one hand, DHM-induced benefits were closely associated with the inhibition of HSCs activation by induction of autophagy. And on the other hand, DHM enhanced the killing effect of hepatic NK cells to the activated HSCs through AhR-NF-κB/STAT3-IFN-γ signaling pathway

Back to article page

Nutrition & Metabolism

ISSN: 1743-7075

Contact us