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Table 4 Odds ratios of incident hyperuricemia stratified by obesity status at baseline and follow-up

From: Independent and joint associations of body mass index, waist circumference, waist-height ratio and their changes with risks of hyperuricemia in middle-aged and older Chinese individuals: a population-based nationwide cohort study

Obesity at baseline

Obesity at follow up

Overall, n

Case, n (%)

OR (95% CI)

Model 1

Model 2

Model 3

General obesity†

 No(a)

No

2451

215 (8.77)

1.00

1.00

1.00

 No(b)

Yes

95

18 (18.95)

3.17 (1.83–5.49)

3.05 (1.76–5.31)

3.04 (1.66–5.59)

 Yes(c)

No

85

8 (9.41)

1.23 (0.58–2.62)

1.04 (0.49–2.23)

0.72 (0.32–1.63)

 Yes(d)

Yes

264

52 (19.70)

3.05 (2.16–4.32)

2.51 (1.75–3.62)

2.22 (1.49–3.31)

Abdominal obesity††

 No(a)

No

1346

94 (6.98)

1.00

1.00

1.00

 No(b)

Yes

319

33 (10.34)

1.83 (1.20–2.81)

1.75 (1.14–2.69)

1.88 (1.18–2.98)

 Yes(c)

No

191

10 (5.24)

0.82 (0.42–1.61)

0.75 (0.38–1.49)

0.60 (0.29–1.23)

 Yes(d)

Yes

1039

156 (15.01)

2.87 (2.15–3.83)

2.48 (1.83–3.35)

2.14 (1.54–2.97)

  1. Model 1: Adjusted for age, gender, residence, marriage, education, smoking history, and drinking status
  2. Model 2: Adjusted for all variables in Model 1 plus hypertension, dyslipidemia, diabetes mellitus, stroke, and depression
  3. Model 3: Adjusted for all variables in Model 2 plus fasting plasma glucose, glycated hemoglobin, total cholesterol, C-reactive protein, blood urea nitrogen, creatinine, and baseline SUA
  4. BMI body mass index, CI confidence interval, OR odds ratio, SUA serum uric acid
  5. Change in obesity status is defined as (a) no obesity, (b) incident obesity, (c) remittent obesity, and (d) persistent obesity
  6. †General obesity is determined using BMI; ††Abdominal obesity is determined using waist circumference
  7. Values in italics are statistically significant (P < 0.05)