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Table 2 Relative abundance of the 8 metabolites related to the AMH decline rate by tertiles of dairy intakea

From: Serum metabolomics study of the association between dairy intake and the anti-müllerian hormone annual decline rate

Dairy groups

Metabolitesb

Tertile 1

Tertile 2

Tertile 3

p-trend

q-valuec

Total dairy

N-Acetyl-d-glucosamine

Ref

− 0.340 (− 0.678, − 0.003)

− 0.313 (− 0.656, 0.030)

0.068

0.154

 

Phosphate

Ref

− 0.435 (− 0.770, − 0.100)

− 0.433 (− 0.774, − 0.093)

0.01

0.048

 

Valine

Ref

− 0.467 (− 0.818, − 0.116)

− 0.492 (− 0.848, − 0.135)

0.006

0.048

 

Leucine

Ref

− 0.523 (− 0.867, − 0.180)

− 0.636 (− 0.986, − 0.287)

< 0.001

0.012

 

Isoleucine

Ref

− 0.384 (− 0.732, − 0.037)

− 0.465 (− 0.818, − 0.112)

0.009

0.048

 

Proline

Ref

− 0.503 (− 0.850, − 0.155)

− 0.657 (− 1.01, − 0.304)

< 0.001

0.012

 

Pyroglutamic acid

Ref

− 0.289 (− 0.647, 0.069)

− 0.229 (− 0.593, 0.135)

0.203

0.287

 

Urea

Ref

− 0.323 (− 0.680, 0.035)

− 0.319 (− 0.683, 0.044)

0.079

0.154

Fermented dairy

N-Acetyl-d-glucosamine

Ref

− 0.102 (− 0.442, 0.237)

− 0.212 (− 0.554, 0.130)

0.223

0.289

 

Phosphate

Ref

− 0.166 (− 0.503, 0.171)

− 0.382 (− 0.721, − 0.042)

0.027

0.081

 

Valine

Ref

− 0.087 (− 0.441, 0.266)

− 0.408 (− 0.764, − 0.502)

0.022

0.081

 

Leucine

Ref

− 0.031 (− 0.382, 0.320)

− 0.388 (− 0.741, − 0.034)

0.026

0.081

 

Isoleucine

Ref

− 0.027 (− 0.378, 0.324)

− 0.295 (− 0.648, 0.058)

0.090

0.154

 

Proline

Ref

0.012 (− 0.343, 0.367)

− 0.374 (− 0.731, − 0.016)

0.032

0.085

 

Pyroglutamic acid

Ref

− 0.041 (− 0.400, 0.318)

− 0.217 (− 0.489, 0.235)

0.483

0.504

 

Urea

Ref

− 0.013 (− 0.370, 0.345)

− 0.307 (− 0.666, 0.053)

0.082

0.154

Milk

N-Acetyl-d-glucosamine

Ref

0.128 (− 0.212, 0.468)

− 0.195 (− 0.536, 0.147)

0.188

0.282

 

Phosphate

Ref

0.110 (− 0.231, 0.450)

− 0.220 (− 0.562, 0.122)

0.146

0.233

 

Valine

Ref

0.108 (− 0.253, 0.469)

− 0.033 (− 0.395, 0.330)

0.774

0.774

 

Leucine

Ref

0.126 (− 0.230, 0.483)

− 0.176 (− 0.534, 0.182)

0.250

0.300

 

Isoleucine

Ref

0.111 (− 0.244, 0.466)

− 0.110 (− 0.467, 0.246)

0.451

0.504

 

Proline

Ref

0.107 (− 0.254, 0.467)

− 0.190 (− 0.552, 0.172)

0.229

0.289

 

Pyroglutamic acid

Ref

− 0.099 (− 0.458, 0.261)

− 0.310 (− 0.671, 0.051)

0.084

0.154

 

Urea

Ref

0.044 (− 0.319, 0.406)

− 0.115 (− 0.479, 0.249)

0.480

0.504

  1. aData is reported as differences in least-squares means of relative abundance of metabolites compared to the tertile 1 as the reference group after adjustment for age, BMI, energy intake, grains and legumes intakes
  2. bMetabolites values are natural log or square root-transformed and auto-scaled
  3. cp value corrected for multiple comparisons using Benjamini–Hochberg procedure
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Nutrition & Metabolism

ISSN: 1743-7075

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