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Table 4 Mediation effects of dairy intakes on AMH fast decline rate through metabolitesa,b

From: Serum metabolomics study of the association between dairy intake and the anti-müllerian hormone annual decline rate

Metabolitec

Effect of M on Yd

Indirect effectf

Βetae (95% CIs)

p value

Beta (95% CIs)

SE

Phosphate

0.66 (0.26, 1.06)

0.001

− 0.11 (− 0.24, − 0.03)

0.059

BCAAs

0.20 (0.07, 0.33)

0.003

− 0.11 (− 0.25, − 0.02)

0.053

Proline

0.40 (0.07, 0.74)

0.019

− 0.09 (− 0.22, − 0.01)

0.051

Urea

0.31 (− 0.02, 0.65)

0.064

− 0.05 (− 0.15, 0.003)

0.042

Phosphate + BCAAs + proline

0.13 (0.05, 0.22)

0.002

− 0.12 (− 0.26, − 0.04)

0.057

  1. AMH anti-Müllerian hormone, BCAAs Branched-chain amino acids
  2. aAdjusted for age and BMI at metabolomics measurement, energy intake, dietary intakes of legumes and grains (g/1000 kcal)
  3. bThe AMH fast decline rate was defined as yearly decline rates ≥ of 5.93% based on this variable's third tertile
  4. cNatural log or square root-transformed
  5. dEffects of mediators (metabolites) on AMH fast decline rate
  6. eStandardized value
  7. fEstimated using boot-strapping
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Nutrition & Metabolism

ISSN: 1743-7075

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