Exogenous L-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring CPT1 activity

Table 1 Serum parameters in healthy subjects and burn patients

Parameters	Healthy subjects (n = 10)	Burn patients (n = 20)	p value
ALT (U/L)	15.70 ± 5.56	34.05 ± 7.44	< 0.0001
AST (U/L)	17.20 ± 6.03	58.70 ± 13.65	< 0.0001
LDH (U/L)	158.60 ± 18.21	530.10 ± 199.10	< 0.0001
TG (mmol/mL)	0.99 ± 0.27	1.15 ± 0.29	n.s
OCT (ng/mL)	7.47 ± 0.73	113.48 ± 34.11	< 0.0001
b-HB (mmol/L)	108.80 ± 10.54	14.27 ± 5.48	< 0.0001
Carnitine ug/L)	48.10 ± 7.13	11.08 ± 4.45	< 0.0001

Serum ALT, AST, LDH, TG, OCT, β-HB, and carnitine levels were analyzed using an auto-analyzer after burn injury (> 30% TBSA, within 24 h). Data are expressed as means ± SD. ns, not significant, Student’s t-test was used to determine the significance of differences (P-value)

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