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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic β-cells

Fig. 2

Dose-dependent effect of diazoxide, nifedipine, and verapamil on the effect of stearic acid (SA) on cell growth and viability in NES2Y and 1.1B4 cells. The data shown were obtained in one representative experiment of at least three independent experiments. The number of living cells was determined after 48 h of incubation. Each column represents the mean of at least four separate cultures ± SEM. * p < 0.05, ** p < 0.001 when comparing the number of cells treated with the respective inhibitor together with SA and cells with SA only. The dotted line represents the number of cells of the inoculum. DMSO was used as vehicle

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