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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis in mice fed with high AGEs-fat diet

Fig. 2

DSS-induced colitis, inflammatory mediators and histological score. a Disease activity index, b Percentage of initial body weight, c colon weight to length, d MPO activity, e mRNA expression of IL-6, f Histological score (at least 5 parts were evaluated for each sample), and g Representative images of H&E staining of distal colonic sections: red arrow 1 shows neutrophils and red arrow 2 indicate cryptitis. HE: herbal extract; ND: normal diet; HFD: high AGEs-fat diet; HD: high dose; LD: low dose; MD: mid dose; DSS: 2.5% dextran sulphate sodium. HS: histological score; MPO: myeloperoxidase. Data as mean with 95% CI, n = 6 per group. * and ** respectively represents p < 0.05 and p < 0.01 (significant difference between the groups)

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