Association between hypertension and coffee drinking based on CYP1A2 rs762551 single nucleotide polymorphism in Taiwanese

Table 3 Multiple logistic regression model showing the association between coffee drinking and hypertension grouped into the rs762551 genotypes

Variables	rs762551 AA			rs762551 AC + CC
Variables	OR	95% CI	p-value	OR	95% CI	p-value
Coffee drinking (Reference: No)
Yes	0.979	0.862–1.112	0.7433	0.806	0.722–0.900	0.0001
Tea drinking (Reference: No)
Yes	0.945	0.817–1.092	0.4419	1.024	0.905–1.160	0.7034
Sex (Reference: Women)
Men	1.256	1.078–1.464	0.0035	1.229	1.078–1.402	0.0021
Age	1.096	1.088–1.105	< 0.0001	1.092	1.084–1.099	< 0.0001
BMI (Reference: Normal)
Underweight	0.285	0.131–0.616	0.0014	0.183	0.086–0.392	< 0.0001
Overweight	1.910	1.646–2.216	< 0.0001	2.100	1.847–2.389	< 0.0001
Obesity	4.290	3.659–5.030	< 0.0001	4.534	3.960–5.190	< 0.0001
Cigarette smoking (Reference: Never)
Former	1.200	0.980–1.469	0.0779	1.133	0.951–1.349	0.1612
Current	0.882	0.675–1.153	0.3596	1.121	0.894–1.407	0.3225
Alcohol drinking (Reference: Never)
Former	1.515	1.142–2.009	0.0039	1.482	1.170–1.878	0.0011
Current	1.471	1.154–1.876	0.0018	1.283	1.040–1.584	0.0199
Exercise(Reference: No)
Yes	1.006	0.883–1.145	0.9341	1.051	0.939–1.177	0.3839

Interactions coffee drinking*rs762551 p-value = 0.0303, tea drinking*rs762551 p-value = 0.4183. OR: odds ratio, CI: confidence interval

ISSN: 1743-7075