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Table 2 Enrichment analysis of the second trimester group

From: Discovery of metabolic biomarkers for gestational diabetes mellitus in a Chinese population

Pathway associated metabolite sets

Enriched compounds

Total

Hits

Raw p

Holm p

FDR

Alpha linolenic acid and linoleic acid metabolism

Linoleic acid; alpha-linolenic acid; docosahexaenoic acid; adrenic acid; 8,11,14-eicosatrienoic acid

19

5

0.000693

0.0679

0.0679

Beta oxidation of very long chain fatty acids

L-carnitine; L-acetylcarnitine;

Caprylic acid

17

3

0.0292

1

1

Valine-leucine-isoleucine degradation

Alpha-ketoisovaleric acid; L-Valine;

L-Isoleucine;3-Methyl-2-oxovaleric acid; L-Leucine; Ketoleucine;

60

6

0.0314

1

1

  1. Pathway associated metabolite sets with p value < 0.05 are shown in the table. Total means total number of metabolites in the metabolite set; Hits mean number of metabolites from GDM patients in the metabolite set; Raw p refers to original p value in the enrichment analysis; Holm p refers to adjusted raw p value by Holm-Bonferroni method; FDR is the false discovery rate