Fig. 6

Schematic diagram of DHM-mediated amelioration of oxidative stress through induction of autophagy via a SIRT3–ATG4B signaling pathway in PA-treated hepatocytes. DHM attenuates PA-induced oxidative stress in hepatocytes through induction of autophagy, which is mediated through the increased expression of SIRT3 and SIRT3-mediated ATG4B deacetylation following DHM treatment