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Table 2 Baseline characteristics of the study population

From: Prevalence and prognostic significance of malnutrition in diabetic patients with coronary artery disease: a cohort study

Characteristic

Risk of Malnutrition

p-value

Overall

Absent

Mild

Moderate

Severe

(n = 12,898)

(n = 5093)

(n = 5984)

(n = 1703)

(n = 118)

Demographic characteristics

Age (years)

63.9 ± 10.1

62.0 ± 9.9

64.5 ± 10.0

67.1 ± 10.0

67.8 ± 9.9

 < 0.001

Female

3852 (29.9)

1755 (34.5)

1638 (27.4)

434 (25.5)

25 (21.2)

 < 0.001

Medical history and Clinical condition

T2DM

12,115 (93.9)

4782 (93.9)

5623 ( 94.0)

1598 ( 93.8)

112 ( 94.9)

0.968

T1DM

12 (0.1)

7 (0.1)

4 (0.1)

1 (0.1)

0 (0.0)

0.605

Anemia

5066 (39.3)

1221 (24.0)

2513 (42.0)

1228 (72.1)

104 (88.1)

 < 0.001

Stroke

995 (7.7)

322 (6.3)

469 (7.8)

186 (10.9)

18 (15.3)

 < 0.001

Hypertension

8825 (68.4)

3429 (67.3)

4106 (68.6)

1201 (70.5)

89 (75.4)

0.028

CKD

3153 (24.4)

789 (15.5)

1476 (24.7)

798 (46.9)

90 (76.3)

 < 0.001

CHF

1553 (12.0)

379 (7.4)

686 (11.5)

435 (25.5)

53 (44.9)

 < 0.001

AF

388 (3.0)

119 (2.3)

180 (3.0)

83 (4.9)

6 (5.1)

 < 0.001

Dialysis history

84 (0.7)

6 (0.1)

23 (0.4)

40 (2.3)

15 (12.7)

 < 0.001

AMI

2361 (18.3)

633 (12.4)

1061 (17.7)

616 (36.2)

51 (43.2)

 < 0.001

Coronary vessels involvement

Two-vessel disease

128 (1.0)

53 (1.0)

65 (1.1)

8 (0.5)

2 (1.7)

0.112

Three-vessel disease

3365 (26.1)

1230 (24.2)

1572 (26.3)

528 (31.0)

35 (29.7)

 < 0.001

Four-vessel disease

2 (0.0)

1 (0.0)

1 (0.0)

0 (0.0)

0 (0.0)

0.952

Procedure

PCI

9748 (75.6)

3793 (74.5)

4517 (75.5)

1344 (78.9)

94 (79.7)

0.002

Laboratory examination

Albumin (g/L)

36.18 ± 4.56

38.93 ± 2.70

35.83 ± 3.74

30.00 ± 3.86

24.54 ± 3.32

 < 0.001

Lymphocyte(109/L)

1.94 ± 0.72

2.25 ± 0.63

1.86 ± 0.68

1.36 ± 0.60

0.90 ± 0.38

 < 0.001

TG (mmol/L)

1.50 (1.10, 2.14)

1.79 (1.32, 2.58)

1.40 (1.03, 1.91)

1.20 (0.92, 1.63)

1.14 (0.89, 1.47)

 < 0.001

TC (mmol/L)

4.45 ± 1.24

5.06 ± 1.08

4.11 ± 1.17

3.89 ± 1.18

3.41 ± 1.05

 < 0.001

LDL-C(mmol/L)

2.72 ± 0.96

3.14 ± 0.87

2.47 ± 0.91

2.35 ± 0.92

2.05 ± 0.81

 < 0.001

HDL-C(mmol/L)

0.95 ± 0.25

1.01 ± 0.24

0.93 ± 0.24

0.87 ± 0.25

0.75 ± 0.23

 < 0.001

CREA(umol/L)

88.10 (73.00, 110.43)

82.53 (69.00, 99.00)

89.10 (74.00,110.00)

108.00 (83.00, 150.00)

150.90 (104.00, 303.30)

 < 0.001

eGFR(ml/min/1.73m2)

74.90 ± 28.34

81.50 ± 25.84

74.73 ± 27.38

60.31 ± 30.54

41.66 ± 27.63

 < 0.001

hs-CRP (mg/L)

4.45 ± 1.24

2.72 (1.04, 6.66)

3.39 (1.04, 9.71)

14.10 (3.65, 40.50)

39.70 (12.92, 78.15)

 < 0.001

Hb (g/L)

129.97 ± 18.18

135.77 ± 15.48

129.43 ± 16.99

116.48 ± 19.95

101.54 ± 22.11

 < 0.001

HbA1c (%)

7.88 ± 1.70

7.89 ± 1.65

7.86 ± 1.71

7.93 ± 1.80

7.78 ± 1.88

0.572

FBG (mmol/L)

9.78 ± 4.62

9.52 ± 4.31

9.73 ± 4.69

10.57 ± 4.93

12.07 ± 6.61

 < 0.001

2hPBG (mmol/L)

12.83 ± 4.41

13.24 ± 4.39

12.67 ± 4.46

12.12 ± 4.12

11.09 ± 5.14

 < 0.001

LVEF (%)

57.73 ± 12.74

60.36 ± 11.45

57.37 ± 12.79

51.68 ± 13.76

49.67 ± 13.20

 < 0.001

Treatment during hospitalization

OADs

7718 (61.1)

3210 (63.5)

3626 (61.9)

838 (51.9)

44 (42.3)

 < 0.001

ACEI/ARB

5807 (46.0)

2363 (46.8)

2688 (45.9)

714 (44.2)

42 (40.4)

0.193

β-blockers

10,400 (82.3)

4247 (84.1)

4803 (82.0)

1266 (78.3)

84 (80.8)

 < 0.001

CCB

3398 (26.9)

1333 (26.4)

1569 (26.8)

458 (28.3)

38 (36.5)

0.062

Statins

12,079 (95.6)

4864 (96.3)

5603 (95.6)

1520 (94.1)

92 (88.5)

 < 0.001

Aspirin

11,623 (92.0)

4697 (93.0)

5393 (92.0)

1450 (89.7)

83 (79.8)

 < 0.001

Diuretic

2203 (17.4)

539 (10.7)

986 (16.8)

620 (38.4)

58 (55.8)

 < 0.001

  1. T2DM Type 2 diabetes mellitus, T1DM type 1 diabetes mellitus, CKD chronic kidney disease, CHF congestive heart failure, AF atrial fibrillation, AMI acute myocardial infarction, PCI percutaneous coronary intervention, TG triglycerides, TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, CREA creatinine, eGFR estimated glomerular filtrationrate, hs-CRP hypersensitive C-reactive protein, Hb hemoglobin, HbA1c glycosylated hemoglobin, FBG Fasting blood glucose, 2hPBG 2 hours postprandial blood glucose, LVEF left ventricular ejection fraction, OADs oral antidiabetic drugs, ACEI/ARB angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, CCB calcium channel blocker