|
Characteristic
|
Risk of Malnutrition
|
p-value
|
|---|
|
Overall
|
Absent
|
Mild
|
Moderate
|
Severe
|
|---|
|
(n = 12,898)
|
(n = 5093)
|
(n = 5984)
|
(n = 1703)
|
(n = 118)
|
|---|
|
Demographic characteristics
|
|
Age (years)
|
63.9 ± 10.1
|
62.0 ± 9.9
|
64.5 ± 10.0
|
67.1 ± 10.0
|
67.8 ± 9.9
|
< 0.001
|
|
Female
|
3852 (29.9)
|
1755 (34.5)
|
1638 (27.4)
|
434 (25.5)
|
25 (21.2)
|
< 0.001
|
|
Medical history and Clinical condition
|
|
T2DM
|
12,115 (93.9)
|
4782 (93.9)
|
5623 ( 94.0)
|
1598 ( 93.8)
|
112 ( 94.9)
|
0.968
|
|
T1DM
|
12 (0.1)
|
7 (0.1)
|
4 (0.1)
|
1 (0.1)
|
0 (0.0)
|
0.605
|
|
Anemia
|
5066 (39.3)
|
1221 (24.0)
|
2513 (42.0)
|
1228 (72.1)
|
104 (88.1)
|
< 0.001
|
|
Stroke
|
995 (7.7)
|
322 (6.3)
|
469 (7.8)
|
186 (10.9)
|
18 (15.3)
|
< 0.001
|
|
Hypertension
|
8825 (68.4)
|
3429 (67.3)
|
4106 (68.6)
|
1201 (70.5)
|
89 (75.4)
|
0.028
|
|
CKD
|
3153 (24.4)
|
789 (15.5)
|
1476 (24.7)
|
798 (46.9)
|
90 (76.3)
|
< 0.001
|
|
CHF
|
1553 (12.0)
|
379 (7.4)
|
686 (11.5)
|
435 (25.5)
|
53 (44.9)
|
< 0.001
|
|
AF
|
388 (3.0)
|
119 (2.3)
|
180 (3.0)
|
83 (4.9)
|
6 (5.1)
|
< 0.001
|
|
Dialysis history
|
84 (0.7)
|
6 (0.1)
|
23 (0.4)
|
40 (2.3)
|
15 (12.7)
|
< 0.001
|
|
AMI
|
2361 (18.3)
|
633 (12.4)
|
1061 (17.7)
|
616 (36.2)
|
51 (43.2)
|
< 0.001
|
|
Coronary vessels involvement
|
|
Two-vessel disease
|
128 (1.0)
|
53 (1.0)
|
65 (1.1)
|
8 (0.5)
|
2 (1.7)
|
0.112
|
|
Three-vessel disease
|
3365 (26.1)
|
1230 (24.2)
|
1572 (26.3)
|
528 (31.0)
|
35 (29.7)
|
< 0.001
|
|
Four-vessel disease
|
2 (0.0)
|
1 (0.0)
|
1 (0.0)
|
0 (0.0)
|
0 (0.0)
|
0.952
|
|
Procedure
|
|
PCI
|
9748 (75.6)
|
3793 (74.5)
|
4517 (75.5)
|
1344 (78.9)
|
94 (79.7)
|
0.002
|
|
Laboratory examination
|
|
Albumin (g/L)
|
36.18 ± 4.56
|
38.93 ± 2.70
|
35.83 ± 3.74
|
30.00 ± 3.86
|
24.54 ± 3.32
|
< 0.001
|
|
Lymphocyte(109/L)
|
1.94 ± 0.72
|
2.25 ± 0.63
|
1.86 ± 0.68
|
1.36 ± 0.60
|
0.90 ± 0.38
|
< 0.001
|
|
TG (mmol/L)
|
1.50 (1.10, 2.14)
|
1.79 (1.32, 2.58)
|
1.40 (1.03, 1.91)
|
1.20 (0.92, 1.63)
|
1.14 (0.89, 1.47)
|
< 0.001
|
|
TC (mmol/L)
|
4.45 ± 1.24
|
5.06 ± 1.08
|
4.11 ± 1.17
|
3.89 ± 1.18
|
3.41 ± 1.05
|
< 0.001
|
|
LDL-C(mmol/L)
|
2.72 ± 0.96
|
3.14 ± 0.87
|
2.47 ± 0.91
|
2.35 ± 0.92
|
2.05 ± 0.81
|
< 0.001
|
|
HDL-C(mmol/L)
|
0.95 ± 0.25
|
1.01 ± 0.24
|
0.93 ± 0.24
|
0.87 ± 0.25
|
0.75 ± 0.23
|
< 0.001
|
|
CREA(umol/L)
|
88.10 (73.00, 110.43)
|
82.53 (69.00, 99.00)
|
89.10 (74.00,110.00)
|
108.00 (83.00, 150.00)
|
150.90 (104.00, 303.30)
|
< 0.001
|
|
eGFR(ml/min/1.73m2)
|
74.90 ± 28.34
|
81.50 ± 25.84
|
74.73 ± 27.38
|
60.31 ± 30.54
|
41.66 ± 27.63
|
< 0.001
|
|
hs-CRP (mg/L)
|
4.45 ± 1.24
|
2.72 (1.04, 6.66)
|
3.39 (1.04, 9.71)
|
14.10 (3.65, 40.50)
|
39.70 (12.92, 78.15)
|
< 0.001
|
|
Hb (g/L)
|
129.97 ± 18.18
|
135.77 ± 15.48
|
129.43 ± 16.99
|
116.48 ± 19.95
|
101.54 ± 22.11
|
< 0.001
|
|
HbA1c (%)
|
7.88 ± 1.70
|
7.89 ± 1.65
|
7.86 ± 1.71
|
7.93 ± 1.80
|
7.78 ± 1.88
|
0.572
|
|
FBG (mmol/L)
|
9.78 ± 4.62
|
9.52 ± 4.31
|
9.73 ± 4.69
|
10.57 ± 4.93
|
12.07 ± 6.61
|
< 0.001
|
|
2hPBG (mmol/L)
|
12.83 ± 4.41
|
13.24 ± 4.39
|
12.67 ± 4.46
|
12.12 ± 4.12
|
11.09 ± 5.14
|
< 0.001
|
|
LVEF (%)
|
57.73 ± 12.74
|
60.36 ± 11.45
|
57.37 ± 12.79
|
51.68 ± 13.76
|
49.67 ± 13.20
|
< 0.001
|
|
Treatment during hospitalization
|
|
OADs
|
7718 (61.1)
|
3210 (63.5)
|
3626 (61.9)
|
838 (51.9)
|
44 (42.3)
|
< 0.001
|
|
ACEI/ARB
|
5807 (46.0)
|
2363 (46.8)
|
2688 (45.9)
|
714 (44.2)
|
42 (40.4)
|
0.193
|
|
β-blockers
|
10,400 (82.3)
|
4247 (84.1)
|
4803 (82.0)
|
1266 (78.3)
|
84 (80.8)
|
< 0.001
|
|
CCB
|
3398 (26.9)
|
1333 (26.4)
|
1569 (26.8)
|
458 (28.3)
|
38 (36.5)
|
0.062
|
|
Statins
|
12,079 (95.6)
|
4864 (96.3)
|
5603 (95.6)
|
1520 (94.1)
|
92 (88.5)
|
< 0.001
|
|
Aspirin
|
11,623 (92.0)
|
4697 (93.0)
|
5393 (92.0)
|
1450 (89.7)
|
83 (79.8)
|
< 0.001
|
|
Diuretic
|
2203 (17.4)
|
539 (10.7)
|
986 (16.8)
|
620 (38.4)
|
58 (55.8)
|
< 0.001
|
- T2DM Type 2 diabetes mellitus, T1DM type 1 diabetes mellitus, CKD chronic kidney disease, CHF congestive heart failure, AF atrial fibrillation, AMI acute myocardial infarction, PCI percutaneous coronary intervention, TG triglycerides, TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, CREA creatinine, eGFR estimated glomerular filtrationrate, hs-CRP hypersensitive C-reactive protein, Hb hemoglobin, HbA1c glycosylated hemoglobin, FBG Fasting blood glucose, 2hPBG 2 hours postprandial blood glucose, LVEF left ventricular ejection fraction, OADs oral antidiabetic drugs, ACEI/ARB angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, CCB calcium channel blocker
