Table 4 B vitamin biomarkers before and after intervention with a B vitamin-fortified and placebo drink
| Â | Placebo | Active | P value | ||
|---|---|---|---|---|---|
Pre-intervention | Post-intervention | Pre-intervention | Post-intervention | ||
Plasma Total 25(OH)D (nmol/L) | 62.5 (22.4) | 66.9 (17.0) | 59.3 (25.20) | 65.5 (25.8) | 0.727 |
Serum homocysteine (µmol/L) | 11.1 (9.7–12.8) | 11.3 (9.9–13.2) | 11.9 (10.3–15.1) | 10.6 (9.4–13.0) | 0.000240 |
Serum folate (nmol/L) | 18.0 (14.3–22.0) | 16.6 (13.0–21.8) | 15.5 (11.8–21.6) | 17.9 (12.7–23.6) | 0.000439 |
Serum vitamin B12 (pmol/L) | 336 (235–449) | 342 (268–468) | 310 (246–409) | 428 (307–549) | 0.005 |
Plasma PLP (vitamin B6; (nmol/L) | 61.7 (48.6–85.1) | 65.4 (38.3–104.9) | 59.4 (44.5–74.1) | 253.0 (181.0–351.4) | 0.002 |
Riboflavin (EGRac) | 1.29 (1.24–1.35) | 1.30 (1.23–1.36) | 1.34 (1.25–1.43) | 1.14 (1.09–1.23) | 3.2014 × 10–9 |