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Table 1 The effects of C. hypnaeoides on the body weight gain and serum metabolic parameters in C57BL/6 J mice fed a high-fat diet

From: Edible red seaweed Campylaephora hypnaeoides J. Agardh alleviates obesity and related metabolic disorders in mice by suppressing oxidative stress and inflammatory response

Variables Normal HF HF + ChL HF + ChH
Body weight gain 12.3 ± 3.5 24.8 ± 1.9## 21.6 ± 3.7* 20.4 ± 2.1*
Glucose (mg/dL) 97 ± 13 155 ± 12## 104 ± 13** 98 ± 15**
Insulin (ng/mL) 0.51 ± 0.14 2.50 ± 0.90## 0.80 ± 0.32** 0.63 ± 0.05**
HOMA-IR 3.45 ± 1.3 26.9 ± 8.1## 5.76 ± 2.3** 4.32 ± 0.51**
TC (mg/dL) 98 ± 19 187 ± 8## 173 ± 27 169 ± 7*
HDL-C (mg/dL) 58 ± 16 70 ± 7 73 ± 3 71 ± 4
TG (mg/dL) 47 ± 16 35 ± 9 39 ± 11 34 ± 6
ALT (IU/L) 24 ± 9 96 ± 27## 51 ± 35* 52 ± 20**
AST (IU/L) 89 ± 13 130 ± 29## 111 ± 24 102 ± 19*
  1. HOMA-IR homeostatic model assessment-insulin resistance, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglyceride, ALT alanine aminotransferase, AST aspartate aminotransferase
  2. Data were expressed as mean ± SD (n = 6–12). Statistical significance: ##p < 0.01 vs. Normal group, *p < 0.05, **p < 0.01 versus HF group