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Table 2 The effects of C. hypnaeoides on the oxidant, anti-oxidant, and inflammatory markers of the serum and liver in C57BL/6 J mice fed a high-fat diet

From: Edible red seaweed Campylaephora hypnaeoides J. Agardh alleviates obesity and related metabolic disorders in mice by suppressing oxidative stress and inflammatory response

Variables Normal HF HF + ChL HF + ChH
Serum
MDA (nmol/mL) 1.51 ± 0.17 2.64 ± 0.47## 2.11 ± 0.31* 1.85 ± 0.37**
adiponectin (μg/mL) 22.8 ± 0.97 16.2 ± 1.4## 16.7 ± 3.0 20.9 ± 1.8*
TNF-α (pg/mL) 4.21 ± 1.4 10.66 ± 3.3## 8.93 ± 1.7 5.93 ± 2.1*
MCP-1 (pg/mL) 32.7 ± 5.8 45.0 ± 9.7# 35.2 ± 7.3* 26.4 ± 5.9*
Liver
MDA (nmol/mg protein) 6.53 ± 1.3 16.1 ± 4.3## 11.3 ± 2.8 * 10.3 ± 2.0**
GSH (nmol/mg protein) 81.8 ± 15 59.3 ± 18# 65.3 ± 18 77.2 ± 13*
SOD (U/mg protein) 8.34 ± 1.5 5.54 ± 1.5## 6.21 ± 2.3 9.15 ± 3.3*
TNF-α (pg/mg protein) 5.14 ± 1.2 12.35 ± 3.2## 7.67 ± 1.6** 6.51 ± 1.4**
IL-6 (pg/mg protein) 1.47 ± 0.21 2.18 ± 0.45## 1.99 ± 0.44 1.63 ± 0.28*
  1. MDA malondialdehyde, TNF-α tumor necrosis factor α, MCP-1 monocyte chemoattractant protein-1, GSH glutathione, SOD superoxide dismutase
  2. Data were expressed as mean ± SD (n = 6–8). Statistical significance: #p < 0.05, ##p < 0.01 versus Normal group, *p < 0.05, **p < 0.01 versus HF group