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Table 2 The effects of C. hypnaeoides on the oxidant, anti-oxidant, and inflammatory markers of the serum and liver in C57BL/6 J mice fed a high-fat diet

From: Edible red seaweed Campylaephora hypnaeoides J. Agardh alleviates obesity and related metabolic disorders in mice by suppressing oxidative stress and inflammatory response

Variables

Normal

HF

HF + ChL

HF + ChH

Serum

MDA (nmol/mL)

1.51 ± 0.17

2.64 ± 0.47##

2.11 ± 0.31*

1.85 ± 0.37**

adiponectin (μg/mL)

22.8 ± 0.97

16.2 ± 1.4##

16.7 ± 3.0

20.9 ± 1.8*

TNF-α (pg/mL)

4.21 ± 1.4

10.66 ± 3.3##

8.93 ± 1.7

5.93 ± 2.1*

MCP-1 (pg/mL)

32.7 ± 5.8

45.0 ± 9.7#

35.2 ± 7.3*

26.4 ± 5.9*

Liver

MDA (nmol/mg protein)

6.53 ± 1.3

16.1 ± 4.3##

11.3 ± 2.8 *

10.3 ± 2.0**

GSH (nmol/mg protein)

81.8 ± 15

59.3 ± 18#

65.3 ± 18

77.2 ± 13*

SOD (U/mg protein)

8.34 ± 1.5

5.54 ± 1.5##

6.21 ± 2.3

9.15 ± 3.3*

TNF-α (pg/mg protein)

5.14 ± 1.2

12.35 ± 3.2##

7.67 ± 1.6**

6.51 ± 1.4**

IL-6 (pg/mg protein)

1.47 ± 0.21

2.18 ± 0.45##

1.99 ± 0.44

1.63 ± 0.28*

  1. MDA malondialdehyde, TNF-α tumor necrosis factor α, MCP-1 monocyte chemoattractant protein-1, GSH glutathione, SOD superoxide dismutase
  2. Data were expressed as mean ± SD (n = 6–8). Statistical significance: #p < 0.05, ##p < 0.01 versus Normal group, *p < 0.05, **p < 0.01 versus HF group
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Nutrition & Metabolism

ISSN: 1743-7075

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