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Table 2 Unadjusted and adjusted Spearman correlation coefficients of methionine metabolites and metabolic relevant factors

From: Association of serum methionine metabolites with non-alcoholic fatty liver disease: a cross-sectional study

Variables Unadjusted Adjusted
SAM SAH Hcy SAM/SAH SAM SAH Hcy SAM/SAH
BMI 0.129*** 0.172*** 0.170*** − 0.101*** 0.131*** 0.145*** 0.117*** − 0.077***
WHR 0.179*** 0.152*** 0.099*** − 0.055** 0.148*** 0.116*** 0.045* − 0.043*
HOMA-IR 0.126*** 0.076*** 0.098*** 0.017 0.085*** 0.056*** 0.043** 0.010
AST/ALT − 0.126*** − 0.087*** − 0.037 0.020 − 0.083*** − 0.063** − 0.028 0.017
TC (mM) − 0.025 − 0.014 − 0.058** − 0.004 − 0.015 0.003 − 0.062** − 0.028
TG (mM) 0.095*** 0.155*** 0.087*** − 0.108*** 0.048* 0.104*** 0.049* − 0.084***
HDL-C (mM) − 0.131*** − 0.163*** − 0.128*** 0.092*** − 0.099*** − 0.144*** − 0.110*** 0.093***
LDL-C (mM) − 0.053** − 0.002 − 0.023 − 0.038* − 0.045* 0.010 − 0.023 − 0.046*
UA (μM) 0.188*** 0.161*** 0.091*** − 0.075*** 0.159*** 0.112*** 0.046* − 0.049*
hsCRP (mg/L) 0.120*** 0.130*** 0.091*** − 0.073*** 0.066** 0.010 0.022 0.034
SAM (nM) 0.527*** 0.193*** − 0.002 0.476*** 0.172*** 0.063**
SAH (nM) 0.527*** 0.416*** − 0.815*** 0.476*** 0.358*** − 0.768***
Hcy (μM) 0.193*** 0.416*** − 0.341*** 0.172*** 0.358*** − 0.261***
SAM/SAH − 0.002 − 0.815*** − 0.341*** 0.063** − 0.768*** − 0.261***
  1. The adjusted associations between serum methionine metabolites levels and several relevant factors were estimated by partial correlation adjusting for age and sex
  2. *P < 0.05; **P < 0.01; ***P < 0.001