| Quartiles of serum methionine metabolites | P for trend | |||
---|---|---|---|---|---|
Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | ||
SAM (nM) | < 75.05 | 75.05–88.06 | 88.07–110.03 | > 110.04 |  |
 NAFLD (%) | 44.52 | 50.64 | 56.45 | 53.91 | < 0.001 |
  Model 1 | 1.00 | 1.34 (1.08, 1.66) | 1.66 (1.33, 2.06) | 1.43 (1.15, 1.79) | < 0.001 |
  Model 2 | 1.00 | 1.07 (0.83, 1.38) | 1.32 (1.03, 1.70) | 0.99 (0.77, 1.28) | 0.636 |
  Model 3 | 1.00 | 1.01 (0.78, 1.31) | 1.24 (0.96, 1.61) | 0.97 (0.74, 1.26) | 0.795 |
SAH (nM) |  < 11.46 | 11.46–15.69 | 15.70–24.52 | > 24.53 |  |
 NAFLD (%) | 40.48 | 49.21 | 51.28 | 64.58 | < 0.001 |
  Model 1 | 1.00 | 1.38 (1.11, 1.71) | 1.50 (1.21, 1.87) | 2.46 (1.97, 3.08) | < 0.001 |
  Model 2 | 1.00 | 1.16 (0.92, 1.51) | 1.27 (0.99, 1.63) | 1.74 (1.35, 2.24) | < 0.001 |
  Model 3 | 1.00 | 1.16 (0.90, 1.50) | 1.27 (0.98, 1.65) | 1.65 (1.27, 2.14) | < 0.001 |
Hcy (μM) | < 11.33 | 11.33–13.05 | 13.06–16.37 | > 16.38 |  |
 NAFLD (%) | 40.83 | 49.79 | 51.07 | 63.87 | < 0.001 |
  Model 1 | 1.00 | 1.42 (1.15, 1.76) | 1.42 (1.14, 1.76) | 2.41 (1.93, 3.01) | < 0.001 |
  Model 2 | 1.00 | 1.19 (0.93, 1.53) | 1.07 (0.84, 1.38) | 1.73 (1.34, 2.23) | < 0.001 |
  Model 3 | 1.00 | 1.23 (0.96, 1.60) | 1.09 (0.84, 1.41) | 1.63 (1.26, 2.12) | 0.001 |
SAM/SAH | < 4.16 | 4.16–5.74 | 5.75–7.21 | > 7.22 |  |
 NAFLD (%) | 60.26 | 53.79 | 46.75 | 44.57 | < 0.001 |
  Model 1 | 1.00 | 0.77 (0.62, 0.96) | 0.60 (0.41, 0.75) | 0.57 (0.46, 0.71) | < 0.001 |
  Model 2 | 1.00 | 0.81 (0.63, 1.04) | 0.64 (0.50, 0.82) | 0.62 (0.48, 0.80) | < 0.001 |
  Model 3 | 1.00 | 0.80 (0.62, 1.03) | 0.64 (0.49, 0.83) | 0.63 (0.49, 0.83) | < 0.001 |