Fig. 7

Co-treatment with HTGT and EMIQ increased energy expenditure and improved obesity-induced metabolic dysfunction. A Indirect calorimetry analysis of high-fat fed (HFD) mice treated with vehicle control (CTL), mirabegron (Mira, 10 mg/kg) and combination of HTGT and EMIQ (H + E, 100 mg/kg each) (n = 4). B Immunoblot analysis of brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) obtained from HFD fed mice treated with vehicle control (CTL), mirabegron (Mira, 10 mg/kg) and combination of HTGT and EMIQ (H + E, 100 mg/kg each) (n = 6). C Intraperitoneal glucose tolerance test (GTT) of HFD fed mice treated with vehicle control (CTL), mirabegron (Mira, 10 mg/kg) and combination of HTGT and EMIQ (H + E, 100 mg/kg each) (n = 6)