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Table 3 The simple mediation effects of adipokines on the association of CoQ10 with glucolipid metabolic markersa

From: Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial

Markers Adiponectin Resistin
Directly effect Mediation effect Directly effect Mediation effect
HOMA-IRb − 0.15
(− 0.86, 0.56)
− 0.60
(− 1.4, − 0.21)
− 0.25
(− 0.98, 0.49)
− 0.50
(− 1.19, − 0.08)
TGc − 0.16
(− 0.50, 0.17)
− 0.17
(− 0.37, − 0.01)
− 0.16
(− 0.49, 0.18)
− 0.17
(− 0.45, 0.04)
LDL-cd − 0.16
(− 0.43, 0.11)
− 0.14
(− 0.32, − 0.02)
− 0.21
(− 0.49, 0.08)
− 0.09
(− 0.22, 0.01)
  1. aThe CI did not include zero indicates a significant effect
  2. bHOMA-IR, homeostasis model assessment of insulin resistance
  3. cTG, triglyceride
  4. dLDL-c, low-density lipoprotein cholesterol