Fig. 2
From: High fructose induces dysfunctional vasodilatation via PP2A-mediated eNOS Ser1177 dephosphorylation
High fructose downregulates eNOS Ser177 phosphorylation resulting in a reduction in NO production. A Cell viability after stimulation with different concentrations of fructose for 24 h (n = 6). B, C NO production from MVECs after stimulation with fructose for 4 or 24 h (n = 4). D, E Western blot analysis showing the protein expression of eNOS and P-eNOS (Ser1177) in MVECs after stimulation with fructose for 8 h (n = 3). Relative protein levels of P-eNOS (Ser1177) were normalized to that of eNOS. All data are shown as the mean ± SEM. C, control. *P < 0. 05, **P < 0. 01, ***P < 0.001 versus C