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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: l-Arabinose improves hypercholesterolemia via regulating bile acid metabolism in high-fat-high-sucrose diet-fed mice

Fig. 5

l-Arabinose enhances the bile acids excretion and reduces intestinal bile acids reabsorption. Total bile acids content in the feces (A), urine (B) and serum (C), and fecal cholesterol level (D) in HFHSD-fed mice treated with or without l-arabinose for 12 weeks. The ileal mRNA expressions of ASBT, I-BABP, FXR, and FGF15 determined by qRT-PCR analysis (E). The ileal protein expressions of FXR, ASBT, and I-BABP determined by western blotting (F) with densitometric quantification (G). Data are shown as mean ± SEM. #p < 0.05 compared with the control group; ##p < 0.01 compared with the control group; *p < 0.05 compared with the HFHSD-fed group. Ctrl control group, HFHSD HFHSD-fed group, HFHSD + L-Ara HFHSD-fed group treated with l-arabinose

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