Extracellular water to total body water ratio predicts survival in cancer patients with sarcopenia: a multi-center cohort study

Table 1 Univariate and multivariate analysis on the overall survival of ECW/TBW in patients with cancer sarcopenia

Characteristics	Cases	Crude HR (95%CI)	p value	Adjusted HR (95%CI)	p value
Per SD	287	1.30 (1.07–1.58)	0.008	1.13 (0.89–1.42)	0.310
By cut-off value
< 0.395	170		Ref		Ref
≥ 0.395	117	2.25 (1.61–3.14)	< 0.001	1.70 (1.18–2.44)	0.004
By quartile
Q1–Q3 (< 0.400)	221		Ref		Ref
Q4 (≥ 0.400)	66	1.93 (1.34–2.76)	< 0.001	1.49 (1.01–2.19)	0.043

Hazard ratios (HRs) of survival for cancer patients with sarcopenia were calculated using univariate Cox regression model or multivariate Cox regression model. Each subgroup analysis included ECW/TBW (as a continuous variable) as the independent variable and adjusted for age, sex, tumor stage, tumor type, BMI, PG-SGA, and NLR if not stratified by these variables. ECW/TBW: extracellular water/total body water, PG-SGA: patient-generated subjective global assessment, NLR: neutrophil-to-lymphocyte ratio

ISSN: 1743-7075