Total population | CC genotypes | TT + CT genotypes | ||||
---|---|---|---|---|---|---|
DASH diet | Legume-based DASH diet | DASH diet | Legume-based DASH diet | DASH diet | Legume-based DASH diet | |
Participants, n | 150 | 150 | 75 | 75 | 75 | 75 |
Age, years | 55.5 (6.9) | 55.4 (7.1) | 55.1 (6.7) | 55.2 (8.1) | 55.6 (7.1) | 55.5 (6.1) |
Female, n (%) | 85 (56.3) | 86 (57.7) | 42 (56.0) | 45 (60.0) | 43 (56.6) | 41 (55.4) |
hsCRP, mg/dl | 3.6 (1.9–5.0) | 3.7 (2.1–5.0) | 3.6 (2.1–5.4) | 3.7 (1.9–4.8) | 3.5 (1.9–4.6) | 3.8 (2.1–5.2) |
MDA, µM | 5.1 (3.7–7.7) | 5.0 (3.6–8.3) | 5.0 (3.7–7.6) | 5.1 (3.4–8.3) | 5.1 (3.4–8.3) | 4.8 (3.6–7.9) |
TNF-α, pg/ml | 13.0 (11.2–15.9) | 11.4 (9.8–15.8) | 11.4 (9.8–13.4) | 11.4 (9.8–13.4) | 15.2 (12.6–17.9) | 11.4 (9.9–16.5) |
IL-6, pg/ml | 4.3 (3.7–5.4) | 3.8 (3.5–4.6) | 3.9 (3.6–5.2) | 3.7 (3.4–4.7) | 4.5 (4.1–5.7) | 3.9 (3.5–4.6) |
Obese, n (%) | 72 (48.0) | 74 (49.3) | 42 (56.0) | 41 (54.7) | 30 (40.0) | 33 (44.0) |
Physical activity levels, Met h/week | 3.5 (2.7) | 3.3 (2.7) | 3.6 (2.8) | 3.4 (2.3) | 3.3 (2.6) | 3.4 (3.0) |
Academic degree, n (%) | 18 (11.9) | 22 (14.8) | 6 (8.0) | 6 (8.0) | 12 (15.8) | 16 (21.6) |
Medication | ||||||
Antihyperglycemic Medications | ||||||
Metformin, n (%) | 55 (36.7) | 69 (46.0) | 32 (42.7) | 39 (52.0) | 23 (30.7) | 30 (40.0) |
Sulfonylurea, n (%) | 40 (26.5) | 29 (19.3) | 21 (28.0) | 14 (18.7) | 19 (25.3) | 15 (20.0) |
Metformin + sulfonylurea, n (%) | 45 (30.0) | 31 (20.7) | 20 (26.7) | 13 (17.3) | 25 (33.3) | 18 (24.0) |
Metformin + thiazolidinedione, n (%) | 5 (3.3) | 11 (7.3) | 2 (2.7) | 9 (12.0) | 3 (4.0) | 2 (2.7) |
Others, n (%) | 5 (3.3) | 10 (6.7) | 0 (0) | 0 (0) | 5 (6.7) | 10 (13.3) |
Lipid lowering drugs | ||||||
Statin use, n (%) | 86 (57.0) | 84 (56.4) | 47 (62.7) | 42 (56.0) | 39 (51.3) | 43 (57.3) |
Others, n (%) | 1 (0.7) | 4 (2.7) | 0 (0.0) | 2 (2.7) | 1 (1.3) | 2 (2.7) |
Antihypertensive drugs | ||||||
ACE inhibitor/ARB use, n (%) | 52 (34.7) | 48 (32.0) | 28 (37.3) | 26 (34.7) | 24 (32.0) | 22 (29.3) |
Thiazide, n (%) | 7 (4.7) | 2 (1.3) | 3 (4.0) | 1 (1.3) | 4 (5.3) | 1 (1.3) |
Others, n (%) | 10 (6.7) | 8 (5.3) | 8 (10.7) | 4 (5.3) | 2 (2.7) | 4 (5.3) |
Asprin n (%) | 28 (18.7) | 28 (18.7) | 11 (14.6) | 13 (17.3) | 17 (22.7) | 15 (20.0) |
Supplement | ||||||
Vitamin E | 1 (0.7) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (1.3%) | 0 (0%) |
Vitamin D | 32 (21.3) | 34 (22.7) | 17 (22.7) | 18 (24.0) | 15 (20.0) | 16 (21.3) |
Vitamin B complex | 17 (11.3) | 15 (10.0) | 7 (9.3) | 9 (12.0) | 10 (13.3) | 6 (8.0) |
W-3 PUFA fatty acids | 4 (2.7) | 3 (2.0) | 3 (4.0) | 0 (0.0) | 1 (1.3) | 3 (4.0) |