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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: Dihydromyricetin ameliorates diet-induced obesity and promotes browning of white adipose tissue by upregulating IRF4/PGC-1α

Fig. 4

DHM induces the browning of primary adipocytes and increases mitochondrial activity. A Representative images of visual estimation and oil red O staining of primary inguinal adipocytes treated with DHM, scale bar = 100 μm. B RNA expression profiles of the brown fat marker and mitochondrial-related and fatty acid oxidation-related genes in primary inguinal adipocytes. C Western blots of PGC-1α and UCP1 protein in primary inguinal adipocytes. D, E Basal OCR in DHM-treated primary inguinal adipocytes. Data are presented as the mean ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001

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