Table 2 Results of the pathway analysis using MetaboAnalyst v5.0
From: Comprehensive evaluation of caloric restriction-induced changes in the metabolome profile of mice
Tissue | Pathway | Raw p | Holm adjust | FDR | Impact |
|---|---|---|---|---|---|
Heart | Alanine, aspartate and glutamate metabolism | 6.34E−04 | 5.20E−02 | 4.05E−02 | 0.42 |
Arginine biosynthesis | 3.46E−03 | 2.80E−01 | 7.27E−02 | 0.12 | |
Phenylalanine, tyrosine and tryptophan biosynthesis | 2.63E−02 | 1.00E+00 | 2.84E−01 | 0.5 | |
d-Glutamine and d-glutamate metabolism | 3.92E−02 | 1.00E+00 | 3.30E−01 | 0.5 | |
Liver | Alanine, aspartate and glutamate metabolism | 6.61E−03 | 5.55E−01 | 5.55E−01 | 0.22 |
Kidney | Aminoacyl-tRNA biosynthesis | 2.46E−02 | 1.00E+00 | 7.37E−01 | 0.17 |
Brain | Glycerolipid metabolism | 3.15E−02 | 1.00E+00 | 9.26E−01 | 0.24 |
White adipose | Primary bile acid biosynthesis | 5.25E−03 | 4.41E−01 | 4.41E−01 | 0.06 |