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Table 2 Effect of alcohol intake on body/liver weights and indicators of liver injury, lipid peroxidation and hepatic steatosis (n = 10 per group)

From: Absolute quantitative lipidomics reveals lipids profiling in liver of mice with early-stage alcoholic liver disease

 

Pair-fed group

Alcohol-fed group

P value

Body weight (g)

23.10 ± 1.77

23.50 ± 1.22

0.32

Liver weight (g)

0.84 ± 0.09

1.09 ± 0.05

 < 0.001

Liver/Body weight

0.04 ± 0.00

0.05 ± 0.00

 < 0.001

Plasma AST (IU/L)

40.66 ± 7.48

39.07 ± 13.40

0.83

Plasma ALT (IU/L)

39.60 ± 10.88

67.18 ± 17.78

0.049

Plasma TC (μM)

925.0 ± 55.27

932.3 ± 51.95

0.84

Plasma TAG (μM)

484.8 ± 108.2

943.5 ± 12.51

 < 0.001

Liver TC (μM/g)

5.19 ± 0.37

5.30 ± 0.24

0.56

Liver TAG (μM/g)

21.07 ± 6.05

29.68 ± 3.59

0.02

MDA (nmol/mg)

4.89 ± 0.78

14.66 ± 2.31

 < 0.001

SOD (U/mg)

0.47 ± 0.11

0.32 ± 0.06

 < 0.001

  1. AST aspartate aminotransferase, ALT alanine aminotransferase, TC total cholesterol, TAG triacylglycerol, MDA malondialdehyde, SOD superoxide dismutase
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Nutrition & Metabolism

ISSN: 1743-7075

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