Table 3 Metabolic parameters of participants before and after treatment
Variable | Taurine group (n = 60) | Placebo group (n = 60) | MD (95% CI) P-value |
|---|---|---|---|
FBS (mg/dl) | |||
 Baseline | 148.33 ± 53. 5 | 150.27 ± 48. 3 | 1.93 (−22.4 to 17.7), 0.967** |
 End | 123.81 ± 54.22 | 142.43 ± 45.07 | −18.5 (−44.6 to 25.6), 0.583*** |
MD (95% CI), P* | −24.3 (−51.4, 2.6) 0.065 | −7.83 (−23.31, 11.59) 0.431 |  |
HbA1c (%) | |||
 Baseline | 8. 4 ± 3.07 | 8.01 ± 2.43 | −0.38 (−1.4 to 1.6), 0.973** |
 End | 7.36 ± 2.53 | 7.83 ± 1.88 | −0.55 (−1.8 to 1.25), 0.155*** |
MD (95% CI), P* | −1.04 (−3.25, 0.48) 0.316 | −0.17 (−1.58, 1.56) 0.802 |  |
Insulin (mU/mL) | |||
 Baseline | 14.32 ± 5.50 | 14.81 ± 4.32 | −0.78 (−3.1, 2.4), 0.767** |
 End | 10.36 ± 4.31 | 13.35 ± 5.05 | −2.98 (−5.4, −0.3), 0.048*** |
MD (95% CI), P* | −3.96 (−7.74, −0.98), 0.019 | −1.45 (−4.6, 1.7), 0.336 |  |
HOMA-IR Index | |||
 Baseline | 4.26 ± 1.8 | 4.73 ± 1.9 | −0.49 (−1.8, 0.14), 0.849** |
 End | 2.99 ± 1.93 | 3.82 ± 2.10 | −1.17 (−1.85, −0.15), 0.022*** |
MD (95% CI), P* | −1.27 (−2.21, −0.85), 0.013 | −0.90 (−2.2, 0.3), 0.133 |  |
SBP (mmHg) | |||
 Baseline | 124.02 ± 18.46 | 125.22 ± 18.42 | −1.19 (−7.1, 5.9), 0.725** |
 End | 117.12 ± 23.22 | 121.97 ± 27.51 | −17.4 (−10.27, 4.55), 0.304 *** |
MD (95% CI), P* | −6.8 (−13.6, 0.44), 0.051 | −3.25 (−9.2, 3.3), 0.326 |  |
DBP (mmHg) | |||
 Baseline | 81.26 ± 12.94 | 82.38 ± 14.85 | 4.53 (−6.1, 3.1), 0.662** |
 End | 78.29 ± 11.20 | 82.00 ± 17.64 | −3.7 (−7.27, 3.3), 0.178*** |
MD (95% CI), P* | −2.96 (−5.2, −1.01), 0.013 | −0.38 (−3.2, 2.4), 0.791 |  |
TC (mg/dl) | |||
 Baseline | 207.97 ± 23.44 | 200.92 ± 23.43 | 7.04 (−30.1, 20.9), 0.872** |
 End | 170.98 ± 28.44 | 185.12 ± 29.97 | −14.4 (−34.27, 24.4), 0.475*** |
MD (95% CI), P* | −36.21 (−80.6, 16.55), 0.169 | −15.1 (−45.1, 13.8), 0.429 |  |
TG (mg/dl) | |||
 Baseline | 198.44 ± 26.88) | 199.88 ± 24.67 | −1.53 (−9.1, 8.7), 0.975** |
 End | 164.46 ± 26.27 | 188.25 ± 28.33 | −23.4 (−77.2, 3.5), 0.469 *** |
MD (95% CI), P* | −33.21 (−63.6, −24.5), 0.001 | −11.2 (−37.2, 4.5), 0.237 |  |
HDL (mg/dl) | |||
 Baseline | 43.86 ± 38.16 | 42.98 ± 6.72 | 0.88 (−2.1, 1.9), 0.987** |
 End | 45.86 ± 7.19 | 43.83 ± 8.87 | 2.03 (−4.27, 5.55), 0.166*** |
MD (95% CI), P* | 2.01 (−0.5, 3.44), 0.071 | 0.88 (−0.7, 4.4), 0.157 |  |
LDL (mg/dl) | |||
 Baseline | 124.42 ± 25.10 | 130.22 ± 21.86 | −5.7 (−12.1, 17.9), 0.920** |
 End | 100.76 ± 28.43 | 117.45 ± 25.75 | −17.4 (−34.27, −0.55), 0.722*** |
MD (95% CI), P* | −23.21 6.1, 40.1), 0.008 | −12.2 (−25, 3.9), 0.125 |  |