Skip to main content
Fig. 2 | Nutrition & Metabolism

Fig. 2

From: Salvianolic acid B activates chondrocytes autophagy and reduces chondrocyte apoptosis in obese mice via the KCNQ1OT1/miR-128-3p/SIRT1 signaling pathways

Fig. 2

Sal B inhibits histological changes of knee joints and inflammatory response in mice fed with HFD. A Two knee joints per mouse with OA were collected after 21 weeks and stained with H & E (original magnification, 100 ×), Scale bars = 100 μm. B–D Serum levels of TNF-α, IL-6 and leptin were measured by ELISA. E Relative expression levels of p62 and Cleaved-caspase3 were detected by Western blot analysis. F Expression of KCNQ1OT1 was determined by RT-qPCR. n = 6. Data are expressed as means ± SEM. Student’s t test was used for the comparison between 2 groups in this study. *P < 0.05

Back to article page