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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: The potential mechanisms of lactate in mediating exercise-enhanced cognitive function: a dual role as an energy supply substrate and a signaling molecule

Fig. 2

Putative mechanisms of lactate as a signal molecule to regulate cognition. ATP, Adenosine triphosphate; BDNF, Brain-derived neurotrophic factor; cAMP, Cyclic adenosine mono-phosphate; CREB, Cyclic AMP-responsive element-binding protein; ERK, Extracellular regulated protein kinases; Gi, Inhibitory adenylate cyclase G protein; GPR81, G protein-coupled receptor 81; HCAR1, Hydroxycarboxylic acid receptor 1; NLRP3, NLR family pyrin domain containing 3; NMDAR, N-methyl-D-aspartic acid receptor; PKA, Protein kinase A; VEGFA, Vascular Endothelial Growth Factor A; VGF, VGF nerve growth factor inducible

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Nutrition & Metabolism

ISSN: 1743-7075

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