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Table 5 Daily excretion of fecal neutral and acidic sterol in hamsters fed one of the five diets

From: Effects of hawthorn seed oil on plasma cholesterol and gut microbiota

 

NCD

HCD

LHSO

HHSO

PCD

Neutral sterols (mg/hamster/day)

 Coprostanol

0.20 ± 0.09d

0.62 ± 0.17b

0.46 ± 0.12bc

0.38 ± 0.11cd

1.36 ± 0.29a

 Coprostanone

0.01 ± 0.00c

0.01 ± 0.00c

0.01 ± 0.00c

0.02 ± 0.01b

0.04 ± 0.01a

 Cholesterol

0.33 ± 0.07c

0.55 ± 0.10a

0.51 ± 0.11ab

0.44 ± 0.07ac

0.40 ± 0.18bc

 Dihydrocholesterol

0.13 ± 0.02c

0.16 ± 0.02bc

0.19 ± 0.03ab

0.21 ± 0.03a

0.17 ± 0.04b

 Total

0.66 ± 0.08d

1.33 ± 0.27b

1.17 ± 0.15bc

1.05 ± 0.08c

1.98 ± 0.15a

Acidic sterols (mg/hamster/day)

 Lithocholic acid

1.20 ± 0.34c

1.85 ± 0.69c

3.27 ± 1.02b

1.84 ± 0.57c

5.19 ± 1.54a

 Deoxycholic acid

0.08 ± 0.04b

0.07 ± 0.02b

0.14 ± 0.07b

0.08 ± 0.02b

0.42 ± 0.16a

 Chenodeoxycholic acid

0.33 ± 0.21b

0.19 ± 0.09b

0.69 ± 0.26b

0.38 ± 0.11b

5.04 ± 1.78a

 Cholic acid

0.12 ± 0.04c

0.20 ± 0.08bc

0.57 ± 0.20a

0.35 ± 0.06b

0.59 ± 0.28a

 Total

1.73 ± 0.52c

2.31 ± 0.84c

4.66 ± 1.36b

2.65 ± 0.73c

11.25 ± 3.64a

  1. NCD, Non-cholesterol diet; HCD, 0.15% Cholesterol diet; LHSO, Hawthorn seed oil substituting 50% lard; HHSO, Hawthorn seed oil substituting 100% lard; PCD, HCD with 0.5% cholestyramine
  2. Data is expressed as mean ± S.D., where different letters in superscript indicate statistical difference, p < 0.05