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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway

Fig. 5

The expression of proteins in HCC cells treated with alpha-linolenic acid. A Alpha-linolenic acid promoted FXR expression and gradually decreased the expression of β-catenin and cyclin D1 in a time-dependent manner, and similar effects were observed at different doses (100 µM, 200 µM, and 300 µM) in HepG2 cells. B Alpha-linolenic acid promoted FXR expression and gradually decreased the expression of β-catenin and cyclin D1 in a dose-dependent manner, and similar effects were observed at different times(24, 48, and 72 h) in HepG2 cells. C Alpha-linolenic acid promoted FXR expression and gradually decreased the expression of β-catenin and cyclin D1 in a time-dependent manner, and similar results were observed at different doses (100 µM, 200 µM, and 300 µM) in Huh7 cells. D Alpha-linolenic acid promoted FXR expression and gradually decreased the expression of β-catenin and cyclin D1 in a dose-dependent manner, and similar results were observed at different times (24, 48, and 72 h) in Huh7 cells. E Alpha-linolenic acid inhibited the expression of pro-oncogene c-myc

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Nutrition & Metabolism

ISSN: 1743-7075

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