Table 1 Descriptive data of the subjects
From: ALDH7A1 rs12514417 polymorphism may increase ischemic stroke risk in alcohol-exposed individuals
|  | Control n = 16,862 | Ischemic n = 897 | Hemorrhagic n = 70 | p-valuea | p-valueb | |||
|---|---|---|---|---|---|---|---|---|
N (%) | N (%) | N (%) | ||||||
ALDH7A1 rs12514417 | Â | Â | Â | Â | Â | Â | 0.316 | 0.212 |
TT | 11,959 | (70.92) | 615 | (68.56) | 54 | (77.14) | Â | Â |
TG | 4496 | (26.66) | 259 | (28.87) | 13 | (18.57) | Â | Â |
GG | 407 | (2.41) | 23 | (2.56) | 3 | (4.29) | Â | Â |
Sex | Â | Â | Â | Â | Â | Â | 0.099 | 0.211 |
Female | 8729 | (51.77) | 439 | (48.94) | 31 | (44.29) | Â | Â |
Male | 8133 | (48.23) | 458 | (51.06) | 39 | (55.71) | Â | Â |
Smoking | Â | Â | Â | Â | Â | Â | 0.517 | 0.103 |
No | 12,737 | (75.54) | 669 | (74.58) | 47 | (67.14) | Â | Â |
Yes | 4125 | (24.46) | 228 | (25.42) | 23 | (32.86) | Â | Â |
Alcohol intake | Â | Â | Â | Â | Â | Â | 0.085 | 0.022 |
No | 15,135 | (89.76) | 789 | (87.96) | 57 | (81.43) | Â | Â |
Yes | 1727 | (10.24) | 108 | (12.04) | 13 | (18.57) | Â | Â |
Diabetes |  |  |  |  |  |  | < 0.001 | 0.008 |
No | 14,783 | (87.67) | 573 | (63.88) | 54 | (77.14) | Â | Â |
Yes | 2079 | (12.33) | 324 | (36.12) | 16 | (22.86) | Â | Â |
Hypertension |  |  |  |  |  |  | < 0.001 | 0.008 |
No | 13,269 | (78.69) | 353 | (39.35) | 46 | (65.71) | Â | Â |
Yes | 3593 | (21.31) | 544 | (60.65) | 24 | (34.29) | Â | Â |
Hyperlipidemia |  |  |  |  |  |  | < 0.001 | 0.007 |
No | 12,087 | (71.68) | 326 | (36.34) | 40 | (57.14) | Â | Â |
Yes | 4775 | (28.32) | 571 | (63.66) | 30 | (42.86) | Â | Â |
Age (mean ± SD) | 48.32 | ± 10.89 | 58.45 | ± 8.19 | 50.66 | ± 10.64 | < 0.001 | 0.073 |
BMI (mean ± SD) | 24.23 | ± 3.63 | 24.83 | ± 3.65 | 24.51 | ± 4.16 | < 0.001 | 0.531 |