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Table 2 Association of ischemic and hemorrhagic stroke with alcohol intake in rs12514417 individuals

From: ALDH7A1 rs12514417 polymorphism may increase ischemic stroke risk in alcohol-exposed individuals

 

Ischemic stroke

Hemorrhagic stroke

rs12514417(TT)

rs12514417(TG + GG)

rs12514417(TT)

rs12514417(TG + GG)

OR

(95% CI)

OR

(95% CI)

OR

(95% CI)

OR

(95% CI)

Alcohol intake (ref: No)

        

Yes

0.85

(0.64–1.15)

1.7

(1.16–2.50)

1.9

(0.86–4.05)

1.1

(0.29–4.36)

Sex (ref: Female)

        

Male

0.99

(0.81–1.22)

1.1

(0.81–1.50)

1

(0.53–1.98)

2.2

(0.61–7.80)

Age

1.07

(1.06–1.08)

1.1

(1.06–1.10)

1

(0.98–1.04)

1

(0.93–1.04)

Education (ref: Elementary School)

        

Junior & Senior High School

1.01

(0.77–1.32)

1.3

(0.84–1.99)

0.7

(0.24–1.85)

1.7

(0.20-14.18)

University & above

0.8

(0.60–1.07)

1.2

(0.73–1.81)

0.6

(0.23–1.83)

0.6

(0.06–5.40)

Smoking (ref: No)

        

Yes

1.04

(0.83–1.32)

0.7

(0.52–1.03)

1.1

(0.52–2.20)

1.4

(0.42–4.46)

Physical activity (ref: No)

        

Yes

1.08

(0.90–1.29)

1

(0.77–1.30)

0.7

(0.39–1.26)

1.5

(0.51–4.19)

BMI

1.01

(0.98–1.04)

1

(0.94–1.01)

1

(0.88–1.04)

1

(0.90–1.18)

Diabetes (ref: No)

        

Yes

1.54

(1.27–1.87)

1.3

(0.96–1.75)

0.8

(0.33–1.72)

9

(2.54–32.09)

Hypertension (ref: No)

        

Yes

2.53

(2.07–3.09)

1.9

(1.45–2.59)

1.5

(0.76–2.98)

1

(0.27–3.46)

Hyperlipidemia (ref: No)

        

Yes

1.62

(1.32–1.98)

1.7

(1.27–2.27)

1.7

(0.90–3.27)

0.7

(0.19–2.29)

  1. Alcohol intake*rs12514417 in Ischemic stroke, p = 0.0266.; Alcohol intake*rs12514417 in Hemorrhagic stroke, p = 0.9101