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Table 1 Baseline characteristics in 190 patients receiving parenteral nutrition

From: The association between parenteral nutrition and pancreatic injury in adult patients: a retrospective observational study

Variables

Pancreatic injury

p value

No (n = 110)

Yes (n = 80)

Clinical features

   

Age, y

62.0±13.1

61.5±12.9

0.82

Sex, woman, %

27.3% (30)

43.8% (35)

0.02

BMI, kg/m2

21.7±3.3

21.7±3.4

0.91

Fasted, yes, %

63.6% (70)

81.3% (65)

0.008

Surgery, yes, %

78.2% (86)

77.5% (62)

0.91

Diabetes mellitus, yes, %

20.0% (22)

12.5% (10)

0.17

Cancer, yes, %

74.5% (82)

60.0% (48)

0.03

Infection, yes, %

14.5% (16)

23.8% (19)

0.11

Gastrointestinal dysfunction, yes, %

48.2% (53)

50.0% (40)

0.80

Fistula, yes, %

12.7% (14)

13.8% (11)

0.84

PN solution

   

Duration of PN, d*

14 (10.0, 20.0)

15 (12.0, 22.0)

0.53

Duration of EN, d*

4.0 (0.0, 10.0)

0.5 (0.0, 9.0)

0.18

Duration of oral-intake, d*

2.0 (0.0, 10.0)

3.0 (0.0, 7.0)

0.55

Avg PN-ECBW, kcal/kg/d

18.1 ± 5.6

19.7 ± 5.3

0.04

Avg PN-EIBW, kcal/kg/d

17.6 ± 3.9

19.3 ± 3.7

0.003

Avg PN-E/total-E, %

68.0 ± 19.1

77.4 ± 15.3

0.001

Biomedical parameters

   

WBC, 109/L*

8.0 (6.0, 12.0)

9.8 (6.9, 13.1)

0.05

CRP, mg/L*

39.1 (10.2, 101.3)

40.2 (13.4, 115.0)

0.95

FBG, mmol/L

6.2 ± 2.5

6.5 ± 2.9

0.46

ALT, IU/L*

15.0 (10.0, 23.3)

19.5 (9.3, 36.8)

0.51

AST, IU/L*

18.5 (13.0, 28.0)

21.5 (15.3, 37.8)

0.08

AKP, IU/L*

69.0 (52.0, 88.8)

68.0 (54.3, 85.8)

0.47

γ-GT, IU/L*

25.0 (14.0, 44.5)

22.5 (13.0, 62.0)

0.38

TBI, µmol/L*

12.3 (8.4, 16.0)

10.3 (7.6, 14.7)

0.96

DBI, µmol/L*

4.8 (3.2, 6.5)

4.4 (3.2, 7.4)

0.46

TBA, µmol/L*

2.1 (0.6, 5.2)

1.7 (0.7, 4.7)

0.82

ALB, g/L

33.1 ± 4.9

32.3 ± 6.2

0.36

Pre-ALB, mg/L

151.2 ± 77.5

136.8 ± 59.8

0.17

TC, mmol/L

3.6 ± 1.3

3.2 ± 0.9

0.03

TG, mmol/L*

1.2 (0.8, 1.6)

1.2 (0.9, 1.6)

0.32

HDL, mmol/L

0.9 ± 0.3

0.8 ± 0.3

0.02

LDL, mmol/L

2.0 ± 1.1

1.7 ± 0.7

0.04

FFA, mmol/L

0.6 ± 0.3

0.6 ± 0.3

0.80

eGFR, ml/min/1.73m2

108.8 ± 59.6

98.7 ± 48.9

0.22

  1. Note:
  2. 1.* non-normal distribution, data is shown as median and quartile range
  3. 2. Abbreviation: BMI, body mass index; EN, enteral nutrition; WBC, white blood cell; CRP, C-reactive protein; ALT, alanine transferase; AST, aspartate transferase; AKP, alkaline phosphatase; γ-GT, gamma glutamyl-transferase; TBI, total bilirubin; DBI, direct bilirubin; TBA, total bile acids; ALB, albumin; Pre-ALB, pre-albumin; TC, total cholesterol; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein; FFA, fatty free acids; FBG, fast blood glucose; eGFR, estimated glomerular filtration rate; P-AMY, pancreatic amylase; LP, lipase;
  4. 3. total-E, total energy means the sum of daily energy supply of PN plus EN plus oral-intake
  5. 4. Avg PN-ECBW: daily average energy supply of PN in kcal per kg based on current body weight; Avg PN-EIBW: daily average energy supply of PN in kcal per kg based on ideal body weight
  6. 5. PN-E/total-E, PN energy/total energy means the proportion of daily energy supply of PN in the total energy
  7. 6. Pancreatic injury is defined as confirmed by either abnormal elevated serum level of P-AMY or LP based on the normal range
  8. 7. Gastrointestinal dysfunction is defined as the presence of diarrhea, vomiting, abdominal distension, or intestinal obstruction
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Nutrition & Metabolism

ISSN: 1743-7075

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