| Baseline (2006–2008) | First follow-up (2009–2011) | Second follow-up (2012–2014) | Third follow-up (2015–2017) | Overall mean (95% CI) | P time×group |
---|---|---|---|---|---|---|
eGFR, mL/min/1.73m2 | ||||||
 < 150 | 81.4 ± 11.9 | 80.0 ± 12.3 | 74.6 ± 13.1 | 72.0 ± 12.1 | 77.3 (76.6–78.1) | 0.004 |
150–220 | 80.2 ± 12.1 | 78.5 ± 12.9 | 72.8 ± 13.5 | 70.5 ± 12.9 | 75.9 (75.1–76.6) |  |
 ≥ 220 | 79.6 ± 12.1 | 77.9 ± 13.1 | 73.6 ± 13.2 | 70.8 ± 12.3 | 75.3 (75.0–76.5) |  |
SBP, mmHg | ||||||
 < 150 | 106 ± 12.1 | 110 ± 13.3 | 112 ± 14.2 | 111 ± 14.3 | 109 (108–110) | 0.007 |
150–220 | 108 ± 11.8 | 111 ± 13.8 | 112 ± 15.3 | 112 ± 15.8 | 111 (100–112) |  |
 ≥ 220 | 108 ± 12.4 | 112 ± 13.2 | 113 ± 14.6 | 113 ± 15.2 | 112 (111–113) |  |
DBP, mmHg | ||||||
 < 150 | 75.5 ± 9.1 | 75.0 ± 9.8 | 75.9 ± 10.0 | 76.0 ± 9.2 | 74.1 (73.6–74.7) | 0.489 |
150–220 | 71.5 ± 8.6 | 75.5 ± 9.8 | 75.9 ± 9.6 | 75.5 ± 9.4 | 74.5 (73.9–75.0) |  |
 ≥ 220 | 71.3 ± 9.1 | 75.6 ± 10.3 | 76.3 ± 9.3 | 76.1 ± 9.1 | 74.6 (74.1–75.2) |  |