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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: A novel small compound TOIDC suppresses lipogenesis via SREBP1-dependent signaling to curb MAFLD

Fig. 1

Identification of candidate compounds reducing lipid accumulation through high-content screening (HCS) analysis. A Flow chart depicting the process for screening the potential candidates to reduce lipid accumulation. B Fluorescent images representing the compounds’ effect on the lipid droplets accumulation through HCS analysis. Scale bar, 200 µm. C The comparison between control and TOIDC. Scale bar, 50 µm. D Quantification of the relative fluorescent intensity of TOIDC compared to control. E Fluorescent images representing the TOIDC effect on the lipid accumulation through a 6-well plate. Scale bar, 200 µm. F Quantification of (E). Data are presented as mean ± SEM of three independent biological replicates; *P < 0.05; **P < 0.01; ns no significance

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