Fig. 1

ACE2 deletion tended to increase visceral fat and led to increased adipose leptin in mice. A Image depicting SCAT and EAT from WT and ACE2 KO mice. B Weight of VAT. C Weight of SCAT. D MRI analysis of VAT and SCAT. Representative images for VAT and SCAT. E Relative value of the proportion of VAT volume. F Relative value of the proportion of SCAT volume. G Relative value of the VSR. H Levels of TC in EAT. I Levels of TG in EAT. J Levels of leptin in EAT. K Levels of adiponectin in EAT. Data are represented as mean ± SME from n = 3–5 each group; *p < 0.05 versus WT group. WT, wild-type; ACE2, angiotensin-converting enzyme 2; KO, knock out; SCAT, subcutaneous adipose tissue; EAT, epididymal adipose tissue; MRI, magnetic resonance imaging; TFV, total white fat volume; VAT, visceral adipose tissue; VSR, visceral to subcutaneous fat ratio; TC, total cholesterol; TG, triglycerides