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Table 2 Prospective associations between baseline surrogate indexes of IR with follow-up incident T2D and HBP in two cohort studies

From: Association between surrogate indicators of insulin resistance and risk of type 2 diabetes combined with hypertension among Chinese adults: two independent cohort studies

 

T2D

HBP

T2D + HBP

 

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

Cohort 1

      

 TyG

3.16 (2.47,4.04)

< 0.001

1.39 (1.23,1.57)

< 0.001

3.46 (2.43,4.93)

< 0.001

 TG/HDL

1.00 (1.00,1.01)

0.361

1.00 (1.00,1.01)

0.054

1.00 (0.99,1.02)

0.514

 Mets-IR

1.04 (1.03,1.05)

< 0.001

1.03 (1.02,1.04)

< 0.001

1.04 (1.03,1.06)

< 0.001

Cohort 2

      

 TyG

2.05 (1.81,2.32)

< 0.001

1.17 (1.07,1.28)

< 0.001

2.02 (1.67,2.44)

< 0.001

 TG/HDL

1.01 (1.00,1.02)

0.003

1.01 (1.00,1.02)

0.006

1.01 (1.00,1.02)

0.035

 Mets-IR

1.05 (1.04,1.06)

< 0.001

1.01 (1.00,1.02)

0.013

1.05 (1.03,1.07)

< 0.001

  1. Cohort 1, The functional community cohort; Cohort 2, The China Health and Retirement Longitudinal Study; HR, hazard ratio; CI, confidence intervals; HBP, hypertension; T2D, type 2 diabetes; TyG, triglyceride and glucose index, TG/HDL, triglyceride to high-density lipoprotein ratio, Mets-IR, metabolic score for IR.
  2. Cox proportional hazards models adjusted for age, gender, education, smoking, drinking, exercise, obesity and dyslipidemia