Table 1 Main characteristics of the included studies in the meta‐analysis of weight loss and outcomes after AF ablation
Refences (First author, Year, Country/Region) | Source of individuals | Outcomes | Study design | AF diagnosis | Methods of weight loss | N | Age# (year) Male# (%) BMI# | Weight loss (%) | RR (95% CI) | Follow-up times (months) | Adjusted covariates |
|---|---|---|---|---|---|---|---|---|---|---|---|
Clinical trial | |||||||||||
Gessler 2021, Germany | SORT-AF trial | AF recurrence AF burden | Randomized, open-labeled clinical trial | ECG, ILR interrogation | Lifestyle | 67/66 | 58.7/62.1,64/62, 34.9/34.8 | 4.5 | 1.14 (0.37–3.61) | 12 | NA |
Observational studies | |||||||||||
Pathak 2014, Australian | ARREST-AF Cohort Study | AF recurrence duration and symptoms of AF | Prospective Cohort | ECG | Lifestyle | 149 | 57.7, 63.8, 32.7 | 13.1 | 0.21 (0.09–0.49) | 24 | Multiple procedures, type of AF, poor BP control |
Bunch 2016, USA | LDS Hospital, Intermountain Medical Center | AF recurrence | Prospective Cohort | ECG | NA | 288 | 36.3, 59.3, 36 | 4.5 | 0.73 (0.50–1.10) | 36 | Multivariable adjusted& |
Mohanty 2017, USA | St. David’s Medical Center | AF recurrence symptom severity of AF quality of life | Prospective Cohort | ECG | Lifestyle | 90 | 62.7, 72.2, 37.6 | 20.5 | 0.89 (0.52–1.53) | 12 | NA |
Donnellan 2019, USA | Cleveland Clinic | AF recurrence | Retrospective Cohort | ECG, Holter | Bariatric surgery | 239 | 64.6, 55.6, 41.1 | 20.6 | 0.14 (0.05–0.39) | 60 | HbA1C, presenting rhythm at the time of ablation, EFV, BMI, LA |
Ding 2020, UK | Liverpool Heart and Chest Hospital | AF recurrence | Prospective Cohort | ECG, Holter | Lifestyle | 92 | 64.5, 56.5, 36.0 | 6 | 1.85 (0.70–4.90) | 12 | Sex, type of AF, age |
Y Lau 2020, UK | Glasgow Royal Infirmary | AF recurrence | Prospective Cohort | NA | Lifestyle | 146 | NA, NA, 30.4 | 4.2 | 0.33 (0.29–0.85) | 6 | NA |
Shah 2020, USA | The University of Rochester Medical Center | AF recurrence | Prospective Cohort | NA | NA | 146 | 61, 67,31 | 22 | 0.29 (0.11–0.80) | 12 | Multivariable adjusted& |