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Fig. 3 | Nutrition & Metabolism

Fig. 3

From: A transdermal treatment with MC903 ameliorates diet-induced obesity by reducing visceral fat and increasing myofiber thickness and energy consumption in mice

Fig. 3

MC903 treatment attenuated adipocyte hypertrophy and chronic inflammation in eWAT. A Average size of adipocytes. B, C Quantified numbers of crown-like-structures (CLS) and representative photomicrographs of anti-CD11c immunostaining in eWAT. The arrow indicates CLS. D-F Gene expressions in eWAT. G Effect of VitD3 and MC903 on mRNA expression of Pparg in differentiating 3T3-L1 adipocytes. H Effect of VitD3 and MC903 on isoproterenol-induced glycerol release in 3T3-L1 adipocytes. Data are presented as the mean ± SEM. N = 5–7 (A-C, G), 13–15 (D-F), or 4 (H). *p < 0.05, **p < 0.01 significantly different from Chow mice; †p < 0.05, ††p < 0.01 significantly different from HFD mice

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Nutrition & Metabolism

ISSN: 1743-7075

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