Table 4 Biochemical measurements

HbA1c, %

 Baseline

5.70 (0.90)

5.65 (0.40)

5.65 (0.60)

5.60 (0.30)

5.40 (0.20)

 60 days

5.70 (0.60)

5.55 (0.40)

5.45 (0.50)**

5.40 (0.20)

5.30 (0.20)

 Change

− 0.10 (0.40)

− 0.10 (0.10)

− 0.20 (0.20)

− 0.10 (0.20)

0.00 (0.20)

0.12

GA, %

 Baseline

11.90 (2.40)

11.95 (2.80)

12.05 (1.90)

12.50 (1.30)

11.65 (2.00)

 60 days

11.90 (2.70)*

11.95 (2.60)

12.45 (2.30)*

12.60 (1.40)

12.15 (2.30)*

 Change

0.40 (0.60)

0.30 (0.30)

0.30 (0.50)

0.10 (0.20)

0.20 (0.70)

0.69

FBG, mmol/L

 Baseline

5.60 (0.50)

5.20 (0.30)

5.00 (1.05)

5.00 (1.10)

4.65 (0.80)

 60 days

5.30 (1.10)

5.15 (0.80)

5.25 (1.15)

4.80 (1.40)

4.60 (1.00)

 Change

− 0.30 (0.80)

0.050 (0.80)

0.00 (0.40)

0.00 (0.50)

− 0.05 (0.10)

0.73

HDL-C, mmol/L

 Baseline

1.39 ± 0.33

1.48 ± 0.28

1.41 ± 0.39

1.42 ± 0.31

1.43 ± 0.35

 60 days

1.289 ± 0.33

1.47 ± 0.29

1.36 ± 0.32

1.43 ± 0.34

1.43 ± 0.31

 Change

− 0.11 ± 0.18

− 0.01 ± 0.12

− 0.05 ± 0.11

0.01 ± 0.16

− 0.002 ± 0.10

0.19

LDL-C, mmol/L

 Baseline

3.05 ± 0.86

3.28 ± 0.62

3.41 ± 0.46

3.03 ± 0.65

3.02 ± 0.61

 60 days

3.14 ± 0.79

3.62 ± 0.96

3.33 ± 0.58

3.27 ± 0.55

3.16 ± 0.65

 Change

0.09 ± 0.51

0.34 ± 0.66

− 0.08 ± 0.42

0.25 ± 0.38

0.14 ± 0.33

0.23

TCH, mmol/L

 Baseline

5.06 ± 0.82

5.27 ± 0.68

5.40 ± 0.66

4.94 ± 0.76

4.97 ± 0.71

 60 days

5.08 ± 0.93

5.45 ± 1.05

5.20 ± 0.72

5.09 ± 0.63

4.97 ± 0.75

 Change

0.02 ± 0.69

0.18 ± 0.69

− 0.20 ± 0.46

0.15 ± 0.44

− 0.00 ± 0.36

0.44

TG, mmol/L

 Baseline

1.87 (1.41)

1.44 (1.30)

1.86 (0.86)

1.36 (0.64)

1.20 (0.44)

 60 days

2.50 (1.66)

1.37 (0.81)

1.69 (1.08)

1.31 (0.65)

1.32 (0.57)

 Change

0.23 (1.05)

− 0.08 (0.26)

0.05 (0.75)

0.10 (0.33)

0.03 (0.44)

0.44

Peptide C, ng/mL

 Baseline

2.80 (1.60)

2.80 (1.10)

3.35 (2.00)

2.60 (0.90)

2.85 (1.20)

 60 days

2.70 (1.70)

3.10 (2.10)

3.00 (1.75)

2.90 (1.20)

2.80 (1.10)

 Change

0.10 (0.70)

− 0.10 (0.80)

0.00 (0.95)

0.10 (0.30)

− 0.10 (0.40)

0.70

Insulin, μU/mL

 Baseline

14.30 (7.30)

13.50 (5.90)

18.30 (20.70)

13.70 (5.00)

13.55 (10.30)

 60 days

13 (10.10)

13.70 (12.50)

16.55 (13.75)

15.10 (5.30)*

16.60 (8.50)

 Change

3.30 (8.30)

1.95 (5.10)

0.25 (6.25)

1.50 (4.20)

0.95 (5.00)

0.80