Fig. 2
ChE and risks of incidence and severity of DR. (A) ChE and incidence of DR using the binary logistic regression. (B) ChE and severity of DR using the multinomial logistic regression. *P for trend was tested using the median of each group as a continuous variable in the logistic regression. All P for trend was < 0.05. †Model 1 was adjusted for age and sex. ‡ Model 2 was adjusted for age, sex, BMI, SBP, smoking and drinking status, family history of diabetes, diabetes duration, and glucose-lowering treatment. § Model 3 was adjusted for age, sex, BMI, SBP, smoking and drinking status, family history of diabetes, duration of diabetes, glucose-lowering treatment, HbA1c, ALT, TG, LDL-C, and eGFR. ¶ The effect was scaled by the 1-SD increase of loge-transformed ChE. Abbreviations: DR, diabetic retinopathy; ChE, cholinesterase; RR, risk ratio; CI, confidence interval; BMI, body mass index; SBP, systolic blood pressure; HbA1c, hemoglobin A1c; ALT, alanine aminotransferase; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate