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  1. Inflammation, the key regulator of C-reactive protein (CRP) synthesis, plays a pivotal role in atherothrombotic cardiovascular disease.

    Authors: Panniyammakal Jeemon, Dorairaj Prabhakaran, Lakhmy Ramakrishnan, Ruby Gupta, F Ahmed, KR Thankappan, CC Kartha, Vivek Chaturvedi and KS Reddy

    Citation: Nutrition & Metabolism 2011 8:19

    Content type: Research

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  2. Dietary modification via both caloric and nutrient restriction is associated with multiple health benefits, some of which are related to an improvement in antioxidant status and a decrease in the production of...

    Authors: Richard J Bloomer, Mohammad M Kabir, John F Trepanowski, Robert E Canale and Tyler M Farney

    Citation: Nutrition & Metabolism 2011 8:17

    Content type: Research

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  3. Systemic chronic inflammation is linked to metabolic syndrome, type-2 diabetes, and heart disease. Lipopolysaccharide (LPS), a Gram negative microbial product, triggers inflammation through toll-like-receptor-...

    Authors: Matam Vijay-Kumar, Sally M Vanegas, Nilam Patel, Jesse D Aitken, Thomas R Ziegler and Vijay Ganji

    Citation: Nutrition & Metabolism 2011 8:16

    Content type: Research

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  4. Minimizing the number of muscle biopsies has important methodological implications and minimizes subject discomfort during a stable isotope amino acid infusion. We aimed to determine the reliability of obtaini...

    Authors: Nicholas A Burd, Daniel WD West, Tracy Rerecich, Todd Prior, Steven K Baker and Stuart M Phillips

    Citation: Nutrition & Metabolism 2011 8:15

    Content type: Methodology

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  5. Obesity and metabolic syndrome are important public concerns, and there is increasing demand for effective therapeutic strategies. Flavonoids are expected to improve the risk factors associated with metabolic ...

    Authors: Rieko Suzuki, Masami Tanaka, Masakatsu Takanashi, Aashiq Hussain, Bo Yuan, Hiroo Toyoda and Masahiko Kuroda

    Citation: Nutrition & Metabolism 2011 8:14

    Content type: Research

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  6. β-Hydroxy-β-methylbutyrate (HMβ) supplementation is used to treat cancer, sepsis and exercise-induced muscle damage. However, its effects on animal and human health and the consequences of this treatment in ot...

    Authors: Gustavo D Pimentel, José C Rosa, Fábio S Lira, Nelo E Zanchi, Eduardo R Ropelle, Lila M Oyama, Cláudia M Oller do Nascimento, Marco Túlio de Mello, Sergio Tufik and Ronaldo VT Santos

    Citation: Nutrition & Metabolism 2011 8:11

    Content type: Research

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  7. Coffee consumption is associated with a lower risk of type 2 diabetes. We tested the hypothesis that this is mediated by incretin hormones by measuring the acute effects of decaffeinated coffee and coffee comp...

    Authors: Margreet R Olthof, Aimée E van Dijk, Carolyn F Deacon, Robert J Heine and Rob M van Dam

    Citation: Nutrition & Metabolism 2011 8:10

    Content type: Brief communication

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  8. Reducing dietary energy density has proven to be an effective strategy to reduce energy intakes and promote weight control. This effect appears most robust when a low energy dense preload is consumed before me...

    Authors: Heidi J Silver, Mary S Dietrich and Kevin D Niswender

    Citation: Nutrition & Metabolism 2011 8:8

    Content type: Research

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  9. We have previously shown that krill oil (KO), more efficiently than fish oil, was able to downregulate the endocannabinoid system in different tissues of obese zucker rats.

    Authors: Sebastiano Banni, Gianfranca Carta, Elisabetta Murru, Lina Cordeddu, Elena Giordano, Anna Rita Sirigu, Kjetil Berge, Hogne Vik, Kevin C Maki, Vincenzo Di Marzo and Mikko Griinari

    Citation: Nutrition & Metabolism 2011 8:7

    Content type: Research

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  10. Nut consumption may reduce the risk of developing type 2 diabetes. The aim of the current study was to measure the acute and second-meal effects of morning almond consumption and determine the contribution of ...

    Authors: Alisa M Mori, Robert V Considine and Richard D Mattes

    Citation: Nutrition & Metabolism 2011 8:6

    Content type: Research

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  11. Higher fish or higher docosahexaenoic acid (DHA) intake normally correlates positively with higher plasma DHA level, but recent evidence suggests that the positive relationship between intake and plasma levels...

    Authors: Mélanie Plourde, Raphaël Chouinard-Watkins, Milène Vandal, Ying Zhang, Peter Lawrence, J Thomas Brenna and Stephen C Cunnane

    Citation: Nutrition & Metabolism 2011 8:5

    Content type: Research

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  12. The central feature of NAFLD is a disturbed fatty-acid metabolism with hepatic lipid accumulation. However, the factors that determine the severity of NAFLD, including the role of nutrition, gender, and plasma...

    Authors: Tine M Comhair, Sonia C Garcia Caraballo, Cornelis HC Dejong, Wouter H Lamers and S Eleonore Köhler

    Citation: Nutrition & Metabolism 2011 8:4

    Content type: Research

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  13. Metabolic syndrome (MetS) is associated with an increased risk of the development of atherosclerotic cardiovascular disease (CVD). Interleukin-18 (IL-18), which is a pleiotropic proinflammatory cytokine with i...

    Authors: Minako Yamaoka-Tojo, Taiki Tojo, Kazuki Wakaume, Ryo Kameda, Shinji Nemoto, Naonobu Takahira, Takashi Masuda and Tohru Izumi

    Citation: Nutrition & Metabolism 2011 8:3

    Content type: Research

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  14. Current notions about mechanisms by which catch-up growth predisposes to later type 2 diabetes center upon those that link hyperinsulinemia with an accelerated rate of fat deposition (catch-up fat). Using a ra...

    Authors: Marina Casimir, Paula B de Andrade, Asllan Gjinovci, Jean-Pierre Montani, Pierre Maechler and Abdul G Dulloo

    Citation: Nutrition & Metabolism 2011 8:2

    Content type: Brief communication

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  15. Obesity and osteoporosis, two possibly related conditions, are rapidly expanding health concerns in modern society. Both of them are associated with sedentary life style and nutrition. To investigate the effec...

    Authors: Hongqiang Ma, Tuomas Turpeinen, Mika Silvennoinen, Sira Torvinen, Rita Rinnankoski-Tuikka, Heikki Kainulainen, Jussi Timonen, Urho M Kujala, Paavo Rahkila and Harri Suominen

    Citation: Nutrition & Metabolism 2011 8:1

    Content type: Research

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  16. Milk phospholipids (PLs) reduce liver lipid levels when given as a dietary supplement to mice fed a high-fat diet. We have speculated that this might be due to reduced intestinal cholesterol uptake.

    Authors: Alvin Kamili, Elaine Wat, Rosanna WS Chung, Sally Tandy, Jacquelyn M Weir, Peter J Meikle and Jeffrey S Cohn

    Citation: Nutrition & Metabolism 2010 7:90

    Content type: Research

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  17. Golden-Syrian hamsters have been used as an animal model to assess diet-induced atherosclerosis since the early 1980s. Advantages appeared to include a low rate of endogenous cholesterol synthesis, receptor-me...

    Authors: Alice Dillard, Nirupa R Matthan and Alice H Lichtenstein

    Citation: Nutrition & Metabolism 2010 7:89

    Content type: Review

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  18. The prevalence of type 2 diabetes is increasing worldwide, accounting for 85-95% of all diagnosed cases of diabetes. Clinical trials provide evidence of benefits of low-carbohydrate ketogenic diets in terms of...

    Authors: Judith Farrés, Albert Pujol, Mireia Coma, Jose Luis Ruiz, Jordi Naval, José Manuel Mas, Agustí Molins, Joan Fondevila and Patrick Aloy

    Citation: Nutrition & Metabolism 2010 7:88

    Content type: Research

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  19. Most of the human population in the western world has access to unlimited calories and leads an increasingly sedentary lifestyle. The propensity to undertake voluntary exercise or indulge in spontaneous physic...

    Authors: Alistair V Nunn, Geoffrey W Guy, James S Brodie and Jimmy D Bell

    Citation: Nutrition & Metabolism 2010 7:87

    Content type: Commentary

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  20. Increased visceral adipose tissue (VAT) and intramyocellular lipids (IMCL) are associated with increased metabolic risk. Clinical and DXA body composition measures that are associated with VAT are generally ev...

    Authors: Eray Savgan-Gurol, Miriam Bredella, Melissa Russell, Nara Mendes, Anne Klibanski and Madhusmita Misra

    Citation: Nutrition & Metabolism 2010 7:86

    Content type: Research

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  21. We found marked improvement of glucose tolerance and lower dietary energy intake in ischemic heart disease (IHD) patients after advice to follow a Paleolithic diet, as compared to a Mediterranean-like diet. We...

    Authors: Tommy Jönsson, Yvonne Granfeldt, Charlotte Erlanson-Albertsson, Bo Ahrén and Staffan Lindeberg

    Citation: Nutrition & Metabolism 2010 7:85

    Content type: Research

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  22. Individuals who smoke generally have a lower body mass index (BMI) than nonsmokers. The relative roles of energy expenditure and energy intake in maintaining the lower BMI, however, remain controversial. We te...

    Authors: David P Bradley, Lindsey A Johnson, Zhumin Zhang, Amy F Subar, Richard P Troiano, Arthur Schatzkin and Dale A Schoeller

    Citation: Nutrition & Metabolism 2010 7:81

    Content type: Research

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  23. Olive oil's beneficial effects are not only related to its high content of oleic acid, but also to the antioxidant potential of its polyphenols. In this study, we assess the effects of virgin olive oil and its...

    Authors: Amel Nakbi, Wafa Tayeb, Abir Grissa, Manel Issaoui, Samia Dabbou, Issam Chargui, Meriem Ellouz, Abdelhedi Miled and Mohamed Hammami

    Citation: Nutrition & Metabolism 2010 7:80

    Content type: Research

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  24. Chronic fatigue syndrome (CFS) is a debilitating disease characterized by unexplained disabling fatigue and a combination of accompanying symptoms the pathology of which is incompletely understood. Many CFS pa...

    Authors: Shaheen E Lakhan and Annette Kirchgessner

    Citation: Nutrition & Metabolism 2010 7:79

    Content type: Review

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  25. Dihydrocapsiate (DCT) is a natural safe food ingredient which is structurally related to capsaicin from chili pepper and is found in the non-pungent pepper strain, CH-19 Sweet. It has been shown to elicit the ...

    Authors: TszYing Amy Lee, Zhaoping Li, Alona Zerlin and David Heber

    Citation: Nutrition & Metabolism 2010 7:78

    Content type: Research

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  26. Early dietary exposure can influence susceptibility to obesity and type 2 diabetes later in life. We examined the lasting effects of a high protein or high prebiotic fiber weaning diet when followed by a high ...

    Authors: Alannah D Maurer, Lindsay K Eller, Megan C Hallam, Kim Taylor and Raylene A Reimer

    Citation: Nutrition & Metabolism 2010 7:77

    Content type: Research

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  27. As hyperlipidemia, including hypercholesterolemia (HC) and hypertriglyceridemia (HTN), continue to challenge North America's healthcare systems, patients continue to seek efficacious and safe natural therapies...

    Authors: Christopher PF Marinangeli and Peter JH Jones

    Citation: Nutrition & Metabolism 2010 7:76

    Content type: Commentary

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  28. Estrogen or phytoestrogens treatment has been suggested to improve cognitive function of the brain in postmenopausal women. However, there is lack of information on the mechanism of such treatment on the centr...

    Authors: Meixia Pan, Zhuoneng Li, Victor Yeung and Ruo-Jun Xu

    Citation: Nutrition & Metabolism 2010 7:75

    Content type: Research

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  29. Malignant brain tumors affect people of all ages and are the second leading cause of cancer deaths in children. While current treatments are effective and improve survival, there remains a substantial need for...

    Authors: Phillip Stafford, Mohammed G Abdelwahab, Do Young Kim, Mark C Preul, Jong M Rho and Adrienne C Scheck

    Citation: Nutrition & Metabolism 2010 7:74

    Content type: Research

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  30. Bile acids (BA) have recently been shown to increase energy expenditure in mice, but this concept has not been tested in humans. Therefore, we investigated the relationship between plasma BA levels and energy ...

    Authors: Gemma Brufau, Matthias J Bahr, Bart Staels, Thierry Claudel, Johann Ockenga, Klaus HW Böker, Elizabeth J Murphy, Kris Prado, Frans Stellaard, Michael P Manns, Folkert Kuipers and Uwe JF Tietge

    Citation: Nutrition & Metabolism 2010 7:73

    Content type: Brief communication

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  31. Postprandial hyperglycemia is an early defect of type 2 diabetes and one of primary anti-diabetic targets. Treatment of postprandial hyperglycemia can be achieved by inhibiting intestinal α-glucosidase, the ke...

    Authors: Shelly Hogan, Lei Zhang, Jianrong Li, Shi Sun, Corene Canning and Kequan Zhou

    Citation: Nutrition & Metabolism 2010 7:71

    Content type: Research

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  32. Amyotrophic lateral sclerosis (ALS) is a form of degenerative motor neuron disease. At the end stage of the disease artificial feeding is often required. Nevertheless, very little is known about the energy dem...

    Authors: Waltteri Siirala, Klaus T Olkkola, Tommi Noponen, Arno Vuori and Riku Aantaa

    Citation: Nutrition & Metabolism 2010 7:70

    Content type: Research

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  33. We aimed to characterize the lasting effect of moderate caloric restriction during early pregnancy on offspring energy homeostasis, by focusing on the effects on food intake and body weight as well as on the i...

    Authors: Mariona Palou, Teresa Priego, Juana Sánchez, Andreu Palou and Catalina Picó

    Citation: Nutrition & Metabolism 2010 7:69

    Content type: Research

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  34. A sedentary lifestyle and increased consumption of energy dense food have become more common in many parts of the world. The aim of this study was to study long term effects on body composition after a four we...

    Authors: Åsa Ernersson, Fredrik H Nystrom and Torbjörn Lindström

    Citation: Nutrition & Metabolism 2010 7:68

    Content type: Research

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  35. Macrophage infiltration in adipose tissue together with the aberrant production of pro-inflammatory cytokines has been identified as the key link between obesity and its related metabolic disorders. This study...

    Authors: Ruby LC Hoo, Janice YL Wong, CF Qiao, A Xu, HX Xu and Karen SL Lam

    Citation: Nutrition & Metabolism 2010 7:67

    Content type: Research

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  36. The cellular and molecular mechanisms of adipose tissue biology have been studied extensively over the last two decades. Adipose tissue growth involves both an increase in fat cell size and the formation of ma...

    Authors: Ralf Siegner, Stefan Heuser, Ursula Holtzmann, Jörn Söhle, Andreas Schepky, Thomas Raschke, Franz Stäb, Horst Wenck and Marc Winnefeld

    Citation: Nutrition & Metabolism 2010 7:66

    Content type: Research

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  37. The thermogenic and metabolic properties of capsinoids appear to mimic those of the more pungent sister compound capsaicin. However, few data exist on how capsinoid ingestion affects energy expenditure in huma...

    Authors: Andrea R Josse, Scott S Sherriffs, Andrew M Holwerda, Richard Andrews, Aaron W Staples and Stuart M Phillips

    Citation: Nutrition & Metabolism 2010 7:65

    Content type: Research

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  38. We previously determined that a weight-maintenance, non-ketogenic diet containing 30% carbohydrate (CHO), 30% protein, 40% fat, (30:30:40) (LoBAG30) decreased glycated hemoglobin (%tGHb) from 10.8 to 9.1% over a ...

    Authors: Mary C Gannon, Heidi Hoover and Frank Q Nuttall

    Citation: Nutrition & Metabolism 2010 7:64

    Content type: Research

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  39. Little is known with respect to the metabolic response and the requirements of infected newborns. Moreover, the nutritional needs and particularly the energy metabolism of newborns with sepsis are controversia...

    Authors: Rubens Feferbaum, Cláudio Leone, Arnaldo AF Siqueira, Vitor E Valenti, Paulo R Gallo, Alberto OA Reis, Ary C Lopes, Viviane G Nascimento, Adriana G de Oliveira, Tatiana Dias de Carvalho, Rubens Wajnsztejn, Claudia de Castro Selestrin and Luiz Carlos de Abreu

    Citation: Nutrition & Metabolism 2010 7:63

    Content type: Research

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  40. It is undetermined whether calcium supplementation has an effect on obesity or body composition in postmenopausal women. The purpose of the study is to detect the effect of calcium supplementation on indices o...

    Authors: Jiapeng Zhou, Lan-Juan Zhao, Patrice Watson, Qin Zhang and Joan M Lappe

    Citation: Nutrition & Metabolism 2010 7:62

    Content type: Research

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  41. Calcium (Ca) - fortified foods are likely to play an important role in helping the consumer achieve an adequate Ca intake, especially for persons with a low intake of dairy products. Fish bones have a high Ca ...

    Authors: Marian K Malde, Susanne Bügel, Mette Kristensen, Ketil Malde, Ingvild E Graff and Jan I Pedersen

    Citation: Nutrition & Metabolism 2010 7:61

    Content type: Research

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  42. Conjugated linoleic acid (cis-9, trans-11 CLA) and trans-11 vaccenic acid (VA) are found naturally in ruminant-derived foods. CLA has been shown to have numerous potential health related effects and has been exte...

    Authors: M Miriam Jacome-Sosa, Jing Lu, Ye Wang, Megan R Ruth, David C Wright, Martin J Reaney, Jianheng Shen, Catherine J Field, Donna F Vine and Spencer D Proctor

    Citation: Nutrition & Metabolism 2010 7:60

    Content type: Research

    Published on:

  43. Calorie restriction (CR) and endurance exercise are known to attenuate obesity and improve the metabolic syndrome. The aim of this study was to directly compare the effects of CR and endurance exercise in a mo...

    Authors: Ping Huang, Shoufeng Li, Mengle Shao, Qibin Qi, Feng Zhao, Jia You, Ting Mao, Wenjun Li, Zhen Yan and Yong Liu

    Citation: Nutrition & Metabolism 2010 7:59

    Content type: Research

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