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  1. Insulin resistance is often associated with increased levels of intracellular triglycerides, diacylglycerol and decreased fat β-oxidation. It was unknown if this relationship was present in patients with acute...

    Authors: Melanie G Cree, Bradley R Newcomer, David N Herndon, Ting Qian, Dayoung Sun, Beatrice Morio, Jennifer J Zwetsloot, G Lynis Dohm, Ricki Y Fram, Ronald P Mlcak, Asle Aarsland and Robert R Wolfe

    Citation: Nutrition & Metabolism 2007 4:9

    Content type: Research

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  2. To determine the importance of IgM antibodies against phosphorylcholine (aPC), a novel protective factor for cardiovascular disease (CVD), in a population with a non-western life style as compared with a Swedi...

    Authors: Johan Frostegård, WenJing Tao, Anastasia Georgiades, Lennart Råstam, Ulf Lindblad and Staffan Lindeberg

    Citation: Nutrition & Metabolism 2007 4:7

    Content type: Research

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  3. Malignant brain cancer persists as a major disease of morbidity and mortality in adults and is the second leading cause of cancer death in children. Many current therapies for malignant brain tumors fail to pr...

    Authors: Weihua Zhou, Purna Mukherjee, Michael A Kiebish, William T Markis, John G Mantis and Thomas N Seyfried

    Citation: Nutrition & Metabolism 2007 4:5

    Content type: Research

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  4. Understanding of nonalcoholic steatohepatitis (NASH) is hampered by the lack of a suitable model. Our aim was to investigate whether long term high saturated-fat feeding would induce NASH in rats.

    Authors: Caroline Romestaing, Marie-Astrid Piquet, Elodie Bedu, Vincent Rouleau, Marianne Dautresme, Isabelle Hourmand-Ollivier, Céline Filippi, Claude Duchamp and Brigitte Sibille

    Citation: Nutrition & Metabolism 2007 4:4

    Content type: Research

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  5. Dietary trans-rich and interesterified fats were compared to an unmodified saturated fat for their relative impact on blood lipids and plasma glucose. Each fat had melting characteristics, plasticity and solids f...

    Authors: Kalyana Sundram, Tilakavati Karupaiah and KC Hayes

    Citation: Nutrition & Metabolism 2007 4:3

    Content type: Research

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  6. Surgery, commonly performed after an overnight fast, causes a postoperative decline in the anabolic and glucose lowering insulin-like growth factor-1 (IGF-1). Clinical fasting studies have exhibited a positive...

    Authors: Mats KEB Wallin, Eva Selldén, Staffan Eksborg and Kerstin Brismar

    Citation: Nutrition & Metabolism 2007 4:2

    Content type: Research

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  7. Dietary calcium intake and the renin angiotensin system (RAS) regulate blood pressure (BP) by modulating calcium homeostasis. Despite similar BP regulatory effects, the influence of dietary calcium intake alon...

    Authors: Linda S Pescatello, Debbie Turner, Nancy Rodriguez, Bruce E Blanchard, Gregory J Tsongalis, Carl M Maresh, Valerie Duffy and Paul D Thompson

    Citation: Nutrition & Metabolism 2007 4:1

    Content type: Research

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  8. We report longitudinal changes in the metabolic syndrome (MetS) in 2,458 participants from 480 families in the Family Heart Study. Participants were examined between 1994–96 (FHS-T1) and 2002–03 (FHS-T2), abou...

    Authors: Aldi T Kraja, Ingrid B Borecki, Kari North, Weihong Tang, Richard H Myers, Paul N Hopkins, Donna Arnett, Jonathan Corbett, Avril Adelman and Michael A Province

    Citation: Nutrition & Metabolism 2006 3:41

    Content type: Research

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  9. A Paleolithic diet has been suggested to be more in concordance with human evolutionary legacy than a cereal based diet. This might explain the lower incidence among hunter-gatherers of diseases of affluence s...

    Authors: Tommy Jönsson, Bo Ahrén, Giovanni Pacini, Frank Sundler, Nils Wierup, Stig Steen, Trygve Sjöberg, Martin Ugander, Johan Frostegård, Leif Göransson and Staffan Lindeberg

    Citation: Nutrition & Metabolism 2006 3:39

    Content type: Research

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  10. There has been intense interest in defining the functions of UCP2 and UCP3 during the nine years since the cloning of these UCP1 homologues. Current data suggest that both UCP2 and UCP3 proteins share some fea...

    Authors: Janis S Fisler and Craig H Warden

    Citation: Nutrition & Metabolism 2006 3:38

    Content type: Review

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  11. We have reported arginine-sensitive regulation of LAT1 amino acid transporter (SLC 7A5) in normal rodent hepatic cells with loss of arginine sensitivity and high level constitutive expression in tumor cells. W...

    Authors: Hwei Xian Leong, Carl Simkevich, Anne Lesieur-Brooks, Bonnie W Lau, Celine Fugere, Edmond Sabo and Nancy L Thompson

    Citation: Nutrition & Metabolism 2006 3:37

    Content type: Brief communication

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  12. Anti-epileptic medications encompass a wide range of drugs including anticonvulsants, benzodiazepines, enzyme inducers or inhibitors, with a variety effects, including induction of cytochrome P450 and other en...

    Authors: Helen A Valsamis, Surender K Arora, Barbara Labban and Samy I McFarlane

    Citation: Nutrition & Metabolism 2006 3:36

    Content type: Review

    Published on:

  13. Vitamin C is a cofactor in the biosynthesis of carnitine, a molecule required for the oxidation of fatty acids. A reduction in the ability to oxidize fat may contribute to the reported inverse relationship bet...

    Authors: Carol S Johnston, Corinne Corte and Pamela D Swan

    Citation: Nutrition & Metabolism 2006 3:35

    Content type: Brief communication

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  14. Serum leptin variation is commonly associated with fat percentage (%), body mass index (BMI), and activity. In this investigation, we report population differences in mean leptin levels in healthy men as well ...

    Authors: Richard G Bribiescas and Matthew S Hickey

    Citation: Nutrition & Metabolism 2006 3:34

    Content type: Research

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  15. Glycemic load (GL) is used to quantify the glycemic impact of high-carbohydrate (CHO) foods, but cannot be used for low-CHO foods. Therefore, we evaluated the accuracy of equivalent-glycemic-load (EGL), a meas...

    Authors: Thomas MS Wolever, Alison L Gibbs, Matt Spolar, Elinor V Hitchner and Colette Heimowitz

    Citation: Nutrition & Metabolism 2006 3:33

    Content type: Methodology

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  16. To compare the accuracy of air displacement plethysmography (ADP) and dual energy x-ray absorptionmetry (DXA) in tracking changes in body composition after a 16 month weight loss intervention in overweight and...

    Authors: Cláudia S Minderico, Analiza M Silva, Pedro J Teixeira, Luis B Sardinha, Holly R Hull and David A Fields

    Citation: Nutrition & Metabolism 2006 3:32

    Content type: Research

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  17. Obesity is one of the principal causative factors involved in the development of metabolic syndrome. AMP-activated protein kinase (AMPK) is an energy sensor that regulates cellular metabolism. The role of AMP-...

    Authors: Shailendra Giri, Ramandeep Rattan, Ehtishamul Haq, Mushfiquddin Khan, Rifat Yasmin, Je-song Won, Lyndon Key, Avtar K Singh and Inderjit Singh

    Citation: Nutrition & Metabolism 2006 3:31

    Content type: Research

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  18. An adverse hematological interaction between vitamins E and K has been reported, primarily in patients on anticoagulants. However, little is known regarding circulating levels or tissue concentrations of vitam...

    Authors: Alison Tovar, Clement K Ameho, Jeffrey B Blumberg, James W Peterson, Donald Smith and Sarah L Booth

    Citation: Nutrition & Metabolism 2006 3:29

    Content type: Research

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  19. Resistin is secreted from adipocytes, and high circulating levels have been associated with obesity and insulin resistance. To investigate whether resistin could exert autocrine effects in adipocytes, we expre...

    Authors: Yuchang Fu, Liehong Luo, Nanlan Luo and W Timothy Garvey

    Citation: Nutrition & Metabolism 2006 3:28

    Content type: Research

    Published on:

  20. A response to Louter-van de Haar J, Wielinga PY, Scheurink AJ, Nieuwenhuizen AG: Comparison of the effects of three different (-)-hydroxycitric acid preparations on food intake in rats. Nutr Metabol 2005, 2:23

    Authors: Harry G Preuss, Manashi Bagchi and Debasis Bagchi

    Citation: Nutrition & Metabolism 2006 3:26

    Content type: Letters to the Editor

    Published on:

  21. The large inter-individual variation in weight gain during standardized overfeeding together with a weight gain that is often less than theoretically calculated from the energy excess suggest that there are di...

    Authors: Annemiek MCP Joosen and Klaas R Westerterp

    Citation: Nutrition & Metabolism 2006 3:25

    Content type: Review

    Published on:

  22. The average life span of Mongolians is 62 years for males and 69 years for females. This life span is about 16 years shorter than that of Japanese. Mongolian people generally eat meat, fat and diary products b...

    Authors: Fumio Komatsu, Yasuo Kagawa, Mitsuru Sakuma, Terue Kawabata, Yoshinori Kaneko, Dugee Otgontuya, Ulziiburen Chimedregzen, Luvsanbazar Narantuya and Baatar Purvee

    Citation: Nutrition & Metabolism 2006 3:21

    Content type: Research

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  23. Diets that restrict carbohydrate (CHO) have proven to be a successful dietary treatment of obesity for many people, but the degree of weight loss varies across individuals. The extent to which genetic factors ...

    Authors: Gualberto Ruaño, Andreas Windemuth, Mohan Kocherla, Theodore Holford, Maria Luz Fernandez, Cassandra E Forsythe, Richard J Wood, William J Kraemer and Jeff S Volek

    Citation: Nutrition & Metabolism 2006 3:20

    Content type: Research

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  24. Increasing evidence supports carbohydrate restricted diets (CRD) for weight loss and improvement in traditional markers for cardiovascular disease (CVD); less is known regarding emerging CVD risk factors. We p...

    Authors: Richard J Wood, Jeff S Volek, Steven R Davis, Carly Dell'Ova and Maria Luz Fernandez

    Citation: Nutrition & Metabolism 2006 3:19

    Content type: Research

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  25. Asian Indian immigrants have an increased risk for developing cardiovascular disease (CVD); however, there is very little data examining how the adipokines leptin and adiponectin relate to CVD risk factors suc...

    Authors: Jessica Smith, Maha Al-Amri, Allan Sniderman and Katherine Cianflone

    Citation: Nutrition & Metabolism 2006 3:18

    Content type: Research

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  26. We studied the regulation of brain acetyl CoA carboxylase (ACC) activity during food deprivation and under the influence of hormones of glucose homeostasis: glucagon and insulin. Mice were deprived of food and...

    Authors: Kristophe J Karami, John Coppola, Karthik Krishnamurthy, Domingo J Llanos, Amrita Mukherjee and KV Venkatachalam

    Citation: Nutrition & Metabolism 2006 3:15

    Content type: Research

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  27. The determinants of bone mineral density (BMD) at multiple sites were examined in a fit college population. Subjects were 755 males (mean age = 18.7 years) entering the United States Military Academy. A questi...

    Authors: JA Ruffing, F Cosman, M Zion, Susan Tendy, P Garrett, R Lindsay and JW Nieves

    Citation: Nutrition & Metabolism 2006 3:14

    Content type: Research

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  28. Thyroid abnormalities (hyperthyroid and hypothyroid) are accompanied by changes in intermediary metabolism including alterations in body weight, insulin resistance and lipid profile. The aims of this study wer...

    Authors: Haiying Yu, Yan Yang, Muxun Zhang, Huiling Lu, Jianhua Zhang, Hongwei Wang and Katherine Cianflone

    Citation: Nutrition & Metabolism 2006 3:13

    Content type: Research

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  29. All treatments for obesity, including dietary restriction of carbohydrates, have a goal of reducing the storage of fat in adipocytes. The chief enzyme responsible for the mobilization of FFA from adipose tissu...

    Authors: Fredric B Kraemer and Wen-Jun Shen

    Citation: Nutrition & Metabolism 2006 3:12

    Content type: Review

    Published on:

  30. Conjugated linoleic acid (CLA) is a group of polyunsaturated fatty acids which have been extensively studied in the past two decades. However, conjugated octadecatrienoic acid such as cis-9,trans-11,cis-15 and ci...

    Authors: Mélanie Plourde, Jean-Pierre Sergiel, Jean-Michel Chardigny, Stéphane Grégoire, Paul Angers and Jean-Louis Sébédio

    Citation: Nutrition & Metabolism 2006 3:8

    Content type: Research

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  31. It is speculated that high saturated fat very low carbohydrate diets (VLCARB) have adverse effects on cardiovascular risk but evidence for this in controlled studies is lacking. The objective of this study was...

    Authors: Manny Noakes, Paul R Foster, Jennifer B Keogh, Anthony P James, John C Mamo and Peter M Clifton

    Citation: Nutrition & Metabolism 2006 3:7

    Content type: Research

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  32. Approximately 1/3 of individuals have a high plasma response to dietary cholesterol (hyper-responders). Although increases in both LDL and HDL cholesterol have been observed, limited data exist regarding effec...

    Authors: Christine M Greene, David Waters, Richard M Clark, John H Contois and Maria Luz Fernandez

    Citation: Nutrition & Metabolism 2006 3:6

    Content type: Research

    Published on:

  33. Sphingomyelin (SM) is the major phospholipid in cell membranes and in lipoproteins. In human plasma, SM is mainly found in atherogenic lipoproteins; thus, high levels of SM may promote atherogenesis.

    Authors: Axel Schlitt, Stefan Blankenberg, Daoguang Yan, Hans von Gizycki, Michael Buerke, Karl Werdan, Christoph Bickel, Karl J Lackner, Juergen Meyer, Hans J Rupprecht and Xian-Cheng Jiang

    Citation: Nutrition & Metabolism 2006 3:5

    Content type: Research

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  34. Impaired vasodilatation has been suggested to be caused by inhibition of nitric oxide generation by the recently described asymmetric dimethylarginine (ADMA). In the present study we wanted to explore whether ...

    Authors: Hilde MA Eid, Harald Arnesen, Elsa M Hjerkinn, Torstein Lyberg, Ingrid Ellingsen and Ingebjørg Seljeflot

    Citation: Nutrition & Metabolism 2006 3:4

    Content type: Research

    Published on:

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