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  1. Content type: Review

    It is commonly held that "a calorie is a calorie", i.e. that diets of equal caloric content will result in identical weight change independent of macronutrient composition, and appeal is frequently made to the...

    Authors: Eugene J Fine and Richard D Feinman

    Citation: Nutrition & Metabolism 2004 1:15

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  2. Content type: Research

    To compare the effects of isocaloric, energy-restricted very low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss, body composition, trunk fat mass, and resting energy expenditure (REE) in o...

    Authors: JS Volek, MJ Sharman, AL Gómez, DA Judelson, MR Rubin, G Watson, B Sokmen, R Silvestre, DN French and WJ Kraemer

    Citation: Nutrition & Metabolism 2004 1:13

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  3. Content type: Review

    There are likely many scenarios and pathways that can lead to metabolic syndrome. This paper reviews mechanisms by which the accumulation of visceral adipose tissue (VAT) may contribute to the metabolic syndro...

    Authors: Eric S Freedland

    Citation: Nutrition & Metabolism 2004 1:12

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  4. Content type: Research

    The high fat, low carbohydrate ketogenic diet (KD) was developed as an alternative to fasting for seizure management. While the mechanisms by which fasting and the KD inhibit seizures remain speculative, alter...

    Authors: John G Mantis, Nicole A Centeno, Mariana T Todorova, Richard McGowan and Thomas N Seyfried

    Citation: Nutrition & Metabolism 2004 1:11

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  5. Content type: Review

    The topical role of uric acid and its relation to cardiovascular disease, renal disease, and hypertension is rapidly evolving. Its important role both historically and currently in the clinical clustering phen...

    Authors: Melvin R Hayden and Suresh C Tyagi

    Citation: Nutrition & Metabolism 2004 1:10

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  6. Content type: Brief communication

    Epidemiological studies suggest a non-monotonic effect of alcohol consumption on cardiovascular risk, while there is strong evidence concerning the involvement of homocysteine levels on thrombosis. The aim of ...

    Authors: Christos Pitsavos, Demosthenes B Panagiotakos, Meropi D Kontogianni, Christina Chrysohoou, Yannis Chloptsios, Antonis Zampelas, Antonia Trichopoulou and Christodoulos Stefanadis

    Citation: Nutrition & Metabolism 2004 1:9

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  7. Content type: Research

    Although the effects of resistant starch (RS) on postprandial glycemia and insulinemia have been extensively studied, little is known about the impact of RS on fat metabolism. This study examines the relations...

    Authors: Janine A Higgins, Dana R Higbee, William T Donahoo, Ian L Brown, Melanie L Bell and Daniel H Bessesen

    Citation: Nutrition & Metabolism 2004 1:8

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  8. Content type: Review

    Following a low carbohydrate diet, there is a shift towards more fat and less carbohydrate oxidation to provide energy to skeletal muscle, both at rest and during exercise. This review summarizes recent work o...

    Authors: Sandra J Peters and Paul J LeBlanc

    Citation: Nutrition & Metabolism 2004 1:7

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  9. Content type: Review

    Daily energy expenditure consists of three components: basal metabolic rate, diet-induced thermogenesis and the energy cost of physical activity. Here, data on diet-induced thermogenesis are reviewed in relati...

    Authors: Klaas R Westerterp

    Citation: Nutrition & Metabolism 2004 1:5

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  10. Content type: Research

    Insulin resistance induced by a high fat diet has been associated with alterations in lipid content and composition in skeletal muscle and adipose tissue. Administration of β3-adrenoceptor (β3-AR) agonists was...

    Authors: Christian Darimont, Marco Turini, Micheline Epitaux, Irène Zbinden, Myriam Richelle, Eulàlia Montell, Andreu Ferrer-Martinez and Katherine Macé

    Citation: Nutrition & Metabolism 2004 1:4

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  11. Content type: Review

    The role of amino acids as substrates for protein synthesis is well documented. However, a function for amino acids in modulating the signal transduction pathways that regulate mRNA translation has only recent...

    Authors: Scot R Kimball and Leonard S Jefferson

    Citation: Nutrition & Metabolism 2004 1:3

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  12. Content type: Review

    Impaired physical performance is a common but not obligate result of a low carbohydrate diet. Lessons from traditional Inuit culture indicate that time for adaptation, optimized sodium and potassium nutriture,...

    Authors: Stephen D Phinney

    Citation: Nutrition & Metabolism 2004 1:2

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  13. Content type: Editorial

    A new Open Access journal, Nutrition & Metabolism (N&M) will publish articles that integrate nutrition with biochemistry and molecular biology. The open access process is chosen to provide rapid and accessible di...

    Authors: Richard D Feinman and M Mahmood Hussain

    Citation: Nutrition & Metabolism 2004 1:1

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