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  1. Current nutritional approaches to metabolic syndrome and type 2 diabetes generally rely on reductions in dietary fat. The success of such approaches has been limited and therapy more generally relies on pharma...

    Authors: Anthony Accurso, Richard K Bernstein, Annika Dahlqvist, Boris Draznin, Richard D Feinman, Eugene J Fine, Amy Gleed, David B Jacobs, Gabriel Larson, Robert H Lustig, Anssi H Manninen, Samy I McFarlane, Katharine Morrison, Jørgen Vesti Nielsen, Uffe Ravnskov, Karl S Roth…

    Citation: Nutrition & Metabolism 2008 5:9

    Content type: Review

    Published on:

  2. This study evaluated a specialized whey fraction (Prolibra™, high in leucine, bioactive peptides and milk calcium) for use as a dietary supplement to enhance weight loss.

    Authors: Joy L Frestedt, John L Zenk, Michael A Kuskowski, Loren S Ward and Eric D Bastian

    Citation: Nutrition & Metabolism 2008 5:8

    Content type: Research

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  3. Total body water (TBW) estimations have been used to estimate body composition, particularly fat-free mass, to aid in nutritional interventions, and to monitor hydration status. In the past, bioimpedance spect...

    Authors: Jordan R Moon, Sarah E Tobkin, Michael D Roberts, Vincent J Dalbo, Chad M Kerksick, Michael G Bemben, Joel T Cramer and Jeffrey R Stout

    Citation: Nutrition & Metabolism 2008 5:7

    Content type: Brief communication

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  4. Carbohydrate restricted diets (CRD) consistently lower glucose and insulin levels and improve atherogenic dyslipidemia [decreasing triglycerides and increasing HDL cholesterol (HDL-C)]. We have previously show...

    Authors: Joseph C Ratliff, Gisella Mutungi, Michael J Puglisi, Jeff S Volek and Maria Luz Fernandez

    Citation: Nutrition & Metabolism 2008 5:6

    Content type: Research

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  5. Intravenous infusions of glucose and amino acids increase both nitrogen balance and muscle accretion. We hypothesised that co-infusion of glucose (to stimulate insulin) and essential amino acids (EAA) would ac...

    Authors: Fouzia Sadiq, Leslie A Crompton, Jes R Scaife and Michael A Lomax

    Citation: Nutrition & Metabolism 2008 5:5

    Content type: Research

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  6. Genetic factors that predict responses to diet may ultimately be used to individualize dietary recommendations. We used physiogenomics to explore associations among polymorphisms in candidate genes and changes...

    Authors: Richard L Seip, Jeff S Volek, Andreas Windemuth, Mohan Kocherla, Maria Luz Fernandez, William J Kraemer and Gualberto Ruaño

    Citation: Nutrition & Metabolism 2008 5:4

    Content type: Research

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  7. Dietary potassium supplementation in hypertensive rats is cardioprotective. This protection includes a blood pressure independent reduction in the amount of damage caused by cerebral ischemia. Therefore, we hy...

    Authors: Christine' S Rigsby, David M Pollock and Anne M Dorrance

    Citation: Nutrition & Metabolism 2008 5:3

    Content type: Research

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  8. Consumption of a mixed meal increases postprandial carbohydrate utilization and decreases fat oxidation. On the other hand, acute endurance exercise increases fat oxidation and decreases carbohydrate utilizati...

    Authors: Wiley Long III, Katherine Wells, Virginia Englert, Stacy Schmidt, Matthew S Hickey and Christopher L Melby

    Citation: Nutrition & Metabolism 2008 5:2

    Content type: Research

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  9. The leucine metabolite beta-hydroxy-beta-methylbutyrate (HMB) has been extensively used as an ergogenic aid; particularly among bodybuilders and strength/power athletes, who use it to promote exercise performa...

    Authors: Gabriel J Wilson, Jacob M Wilson and Anssi H Manninen

    Citation: Nutrition & Metabolism 2008 5:1

    Content type: Review

    Published on:

  10. The metabolic syndrome (MetS), in addition to its lipid, metabolic, and anthropomorphic characteristics, is associated with a prothrombotic and the proinflammatory state. However, the relationship of inflammat...

    Authors: Aldi T Kraja, Michael A Province, Donna Arnett, Lynne Wagenknecht, Weihong Tang, Paul N Hopkins, Luc Djoussé and Ingrid B Borecki

    Citation: Nutrition & Metabolism 2007 4:28

    Content type: Research

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  11. Bio F1B hamster is an inbred hybrid strain that is highly susceptible to diet-induced atherosclerosis. We previously reported that feeding a high fat fish oil diet to Bio F1B hamster caused severe hyperlipidaemia...

    Authors: Sukhinder Kaur Cheema and Marion L Cornish

    Citation: Nutrition & Metabolism 2007 4:27

    Content type: Research

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  12. Current methodology of gene expression analysis limits the possibilities of comparison between cells/tissues of organs in which cell size and/or number changes as a consequence of the study (e.g. starvation). ...

    Authors: Maria del Mar Romero, Maria del Mar Grasa, Montserrat Esteve, José Antonio Fernández-López and Marià Alemany

    Citation: Nutrition & Metabolism 2007 4:26

    Content type: Methodology

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  13. Sulfur, after calcium and phosphorus, is the most abundant mineral element found in our body. It is available to us in our diets, derived almost exclusively from proteins, and yet only 2 of the 20 amino acids ...

    Authors: Marcel E Nimni, Bo Han and Fabiola Cordoba

    Citation: Nutrition & Metabolism 2007 4:24

    Content type: Review

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  14. Low carbohydrate diets (LCDs) have been demonstrated to be effective tools for promoting weight loss and an improved plasma lipid profile. Such diets are often associated with increased meat consumption, eithe...

    Authors: Bridget A Cassady, Nicole L Charboneau, Emily E Brys, Kristin A Crouse, Donald C Beitz and Ted Wilson

    Citation: Nutrition & Metabolism 2007 4:23

    Content type: Research

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  15. Intrauterine growth retardation due to maternal under-nutrition increases susceptibility to obesity and insulin resistance. We reported earlier in the offspring of mineral or vitamin restricted rat dams, a hig...

    Authors: Venu Lagishetty, Vijaya Bhanu Nandiwada, Rajender Rao Kalashikam and Raghunath Manchala

    Citation: Nutrition & Metabolism 2007 4:21

    Content type: Brief communication

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  16. Meeting patients' nutritional requirements and preventing malnutrition is a challenge following major surgical procedures. The role of ghrelin in nutritional recovery after non-gastrointestinal major surgery i...

    Authors: Mohsen Nematy, Audrey E Brynes, Philip I Hornick, Michael Patterson, Mohammad A Ghatei, Stephen R Bloom, Stephen J Brett and Gary S Frost

    Citation: Nutrition & Metabolism 2007 4:20

    Content type: Brief communication

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  17. The body mass index (BMI) is the standard parameter for predicting body fat fraction and for classifying degrees of obesity. Currently available regression equations between BMI and fat are based on 2 or 3 par...

    Authors: David G Levitt, Steven B Heymsfield, Richard N Pierson Jr., Sue A Shapses and John G Kral

    Citation: Nutrition & Metabolism 2007 4:19

    Content type: Research

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  18. To determine the influence of menstrual irregularity, oral contraceptive use and other factors on bone mineral density (BMD) and bone size at different skeletal sites in 135 college-aged fit women.

    Authors: Jamie A Ruffing, Jeri W Nieves, Marsha Zion, Susan Tendy, Patricia Garrett, Robert Lindsay and Felicia Cosman

    Citation: Nutrition & Metabolism 2007 4:17

    Content type: Research

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  19. Most studies on lipid lowering diets have focused on the total content of saturated, polyunsaturated and monounsaturated fatty acids. However, the distribution of these fatty acids on the triacylglycerol (TAG)...

    Authors: Tilakavati Karupaiah and Kalyana Sundram

    Citation: Nutrition & Metabolism 2007 4:16

    Content type: Review

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  20. Vascular dysfunction can develop from consumption of an energy-rich diet, even prior to the onset of obesity. However, the roles played by different dietary components remain uncertain. While attempting to dev...

    Authors: Sameer Fatani, Lucy C Pickavance, Claire J Sadler, Joanne A Harrold, Roslyn Cassidy, John PH Wilding and Ebrahim K Naderali

    Citation: Nutrition & Metabolism 2007 4:15

    Content type: Brief communication

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  21. The frequency of Japanese subjects over 20 years old with metabolic syndrome is 45.6% in men but just 16.7% in women. The reason why Japanese male subjects are more susceptible to metabolic syndrome than women...

    Authors: Kyoko Miyasaka, Setsuko Kanai, Minoru Ohta, Ayako Sekime, Saeko Akimoto, Soichi Takiguchi and Akihiro Funakoshi

    Citation: Nutrition & Metabolism 2007 4:14

    Content type: Research

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  22. Age-related macular degeneration (AMD) is a disease with multiple risk factors, many of which appear to involve oxidative stress. Macular pigment, with its antioxidant and light-screening properties, is though...

    Authors: Richard A Bone, John T Landrum, Yisi Cao, Alan N Howard and Francesca Alvarez-Calderon

    Citation: Nutrition & Metabolism 2007 4:12

    Content type: Research

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  23. We evaluated plasma ASP and its precursor C3 in type 2 diabetic men with/without rosiglitazone (ROSI) treatment compared to healthy non-obese men. We tested (1) whether plasma ASP or C3 are altered postprandia...

    Authors: Youssef Tahiri, Fredrik Karpe, Garry D Tan and Katherine Cianflone

    Citation: Nutrition & Metabolism 2007 4:11

    Content type: Research

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  24. Consumption of trans fats is associated with an increase of cardiovascular disease (CVD) risk. To comply with regulatory policies and public health authorities recommendations, trans fats should be replaced in fo...

    Authors: Frédéric Destaillats, Julie Moulin and Jean-Baptiste Bezelgues

    Citation: Nutrition & Metabolism 2007 4:10

    Content type: Letters to the Editor

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  25. Insulin resistance is often associated with increased levels of intracellular triglycerides, diacylglycerol and decreased fat β-oxidation. It was unknown if this relationship was present in patients with acute...

    Authors: Melanie G Cree, Bradley R Newcomer, David N Herndon, Ting Qian, Dayoung Sun, Beatrice Morio, Jennifer J Zwetsloot, G Lynis Dohm, Ricki Y Fram, Ronald P Mlcak, Asle Aarsland and Robert R Wolfe

    Citation: Nutrition & Metabolism 2007 4:9

    Content type: Research

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  26. To determine the importance of IgM antibodies against phosphorylcholine (aPC), a novel protective factor for cardiovascular disease (CVD), in a population with a non-western life style as compared with a Swedi...

    Authors: Johan Frostegård, WenJing Tao, Anastasia Georgiades, Lennart Råstam, Ulf Lindblad and Staffan Lindeberg

    Citation: Nutrition & Metabolism 2007 4:7

    Content type: Research

    Published on:

  27. Malignant brain cancer persists as a major disease of morbidity and mortality in adults and is the second leading cause of cancer death in children. Many current therapies for malignant brain tumors fail to pr...

    Authors: Weihua Zhou, Purna Mukherjee, Michael A Kiebish, William T Markis, John G Mantis and Thomas N Seyfried

    Citation: Nutrition & Metabolism 2007 4:5

    Content type: Research

    Published on:

  28. Understanding of nonalcoholic steatohepatitis (NASH) is hampered by the lack of a suitable model. Our aim was to investigate whether long term high saturated-fat feeding would induce NASH in rats.

    Authors: Caroline Romestaing, Marie-Astrid Piquet, Elodie Bedu, Vincent Rouleau, Marianne Dautresme, Isabelle Hourmand-Ollivier, Céline Filippi, Claude Duchamp and Brigitte Sibille

    Citation: Nutrition & Metabolism 2007 4:4

    Content type: Research

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  29. Dietary trans-rich and interesterified fats were compared to an unmodified saturated fat for their relative impact on blood lipids and plasma glucose. Each fat had melting characteristics, plasticity and solids f...

    Authors: Kalyana Sundram, Tilakavati Karupaiah and KC Hayes

    Citation: Nutrition & Metabolism 2007 4:3

    Content type: Research

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  30. Surgery, commonly performed after an overnight fast, causes a postoperative decline in the anabolic and glucose lowering insulin-like growth factor-1 (IGF-1). Clinical fasting studies have exhibited a positive...

    Authors: Mats KEB Wallin, Eva Selldén, Staffan Eksborg and Kerstin Brismar

    Citation: Nutrition & Metabolism 2007 4:2

    Content type: Research

    Published on:

  31. Dietary calcium intake and the renin angiotensin system (RAS) regulate blood pressure (BP) by modulating calcium homeostasis. Despite similar BP regulatory effects, the influence of dietary calcium intake alon...

    Authors: Linda S Pescatello, Debbie Turner, Nancy Rodriguez, Bruce E Blanchard, Gregory J Tsongalis, Carl M Maresh, Valerie Duffy and Paul D Thompson

    Citation: Nutrition & Metabolism 2007 4:1

    Content type: Research

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  32. We report longitudinal changes in the metabolic syndrome (MetS) in 2,458 participants from 480 families in the Family Heart Study. Participants were examined between 1994–96 (FHS-T1) and 2002–03 (FHS-T2), abou...

    Authors: Aldi T Kraja, Ingrid B Borecki, Kari North, Weihong Tang, Richard H Myers, Paul N Hopkins, Donna Arnett, Jonathan Corbett, Avril Adelman and Michael A Province

    Citation: Nutrition & Metabolism 2006 3:41

    Content type: Research

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  33. A Paleolithic diet has been suggested to be more in concordance with human evolutionary legacy than a cereal based diet. This might explain the lower incidence among hunter-gatherers of diseases of affluence s...

    Authors: Tommy Jönsson, Bo Ahrén, Giovanni Pacini, Frank Sundler, Nils Wierup, Stig Steen, Trygve Sjöberg, Martin Ugander, Johan Frostegård, Leif Göransson and Staffan Lindeberg

    Citation: Nutrition & Metabolism 2006 3:39

    Content type: Research

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  34. There has been intense interest in defining the functions of UCP2 and UCP3 during the nine years since the cloning of these UCP1 homologues. Current data suggest that both UCP2 and UCP3 proteins share some fea...

    Authors: Janis S Fisler and Craig H Warden

    Citation: Nutrition & Metabolism 2006 3:38

    Content type: Review

    Published on:

  35. We have reported arginine-sensitive regulation of LAT1 amino acid transporter (SLC 7A5) in normal rodent hepatic cells with loss of arginine sensitivity and high level constitutive expression in tumor cells. W...

    Authors: Hwei Xian Leong, Carl Simkevich, Anne Lesieur-Brooks, Bonnie W Lau, Celine Fugere, Edmond Sabo and Nancy L Thompson

    Citation: Nutrition & Metabolism 2006 3:37

    Content type: Brief communication

    Published on:

  36. Anti-epileptic medications encompass a wide range of drugs including anticonvulsants, benzodiazepines, enzyme inducers or inhibitors, with a variety effects, including induction of cytochrome P450 and other en...

    Authors: Helen A Valsamis, Surender K Arora, Barbara Labban and Samy I McFarlane

    Citation: Nutrition & Metabolism 2006 3:36

    Content type: Review

    Published on:

  37. Vitamin C is a cofactor in the biosynthesis of carnitine, a molecule required for the oxidation of fatty acids. A reduction in the ability to oxidize fat may contribute to the reported inverse relationship bet...

    Authors: Carol S Johnston, Corinne Corte and Pamela D Swan

    Citation: Nutrition & Metabolism 2006 3:35

    Content type: Brief communication

    Published on:

  38. Serum leptin variation is commonly associated with fat percentage (%), body mass index (BMI), and activity. In this investigation, we report population differences in mean leptin levels in healthy men as well ...

    Authors: Richard G Bribiescas and Matthew S Hickey

    Citation: Nutrition & Metabolism 2006 3:34

    Content type: Research

    Published on:

  39. Glycemic load (GL) is used to quantify the glycemic impact of high-carbohydrate (CHO) foods, but cannot be used for low-CHO foods. Therefore, we evaluated the accuracy of equivalent-glycemic-load (EGL), a meas...

    Authors: Thomas MS Wolever, Alison L Gibbs, Matt Spolar, Elinor V Hitchner and Colette Heimowitz

    Citation: Nutrition & Metabolism 2006 3:33

    Content type: Methodology

    Published on:

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