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  1. Content type: Research

    The Family Blood Pressure Program is an ongoing, NHLBI-sponsored, multi-center program to study the genetic determinants of high blood pressure. The goal of this particular study was to study patterns of metab...

    Authors: Aldi T Kraja, DC Rao, Alan B Weder, Thomas H Mosley, Stephen T Turner, Chao Agnes Hsiung, Thomas Quertermous, Richard Cooper, J David Curb and Michael A Province

    Citation: Nutrition & Metabolism 2005 2:17

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  2. Content type: Review

    A low fat, high carbohydrate diet in combination with regular exercise is the traditional recommendation for treating diabetes. Compliance with these lifestyle modifications is less than satisfactory, however,...

    Authors: Surender K Arora and Samy I McFarlane

    Citation: Nutrition & Metabolism 2005 2:16

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  3. Content type: Research

    Obesity is associated with insulin resistance that can often be improved by caloric restriction and weight reduction. Although many physiological changes accompanying insulin resistance and its treatment have ...

    Authors: R Michael Raab, John Bullen, Joanne Kelleher, Christos Mantzoros and Gregory Stephanopoulos

    Citation: Nutrition & Metabolism 2005 2:15

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  4. Content type: Research

    Plasma total homocysteine (tHcy) is commonly elevated in persons with diabetes. This may be due to effects of insulin and/or glucose and/or metabolic control on the metabolism or plasma levels of tHcy. This st...

    Authors: Glen E Duncan, Sierra M Li and Xiao-Hua Zhou

    Citation: Nutrition & Metabolism 2005 2:13

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  5. Content type: Research

    Energy and Zinc (Zn) deficiencies have been associated with nutritional related growth retardation as well as growth hormone (GH) resistance. In this study, the relationship between suboptimal energy and/or Zn...

    Authors: Russell Rising, Julio F Scaglia, Conrad Cole, Rozalia Tverskaya, Debora Duro and Fima Lifshitz

    Citation: Nutrition & Metabolism 2005 2:10

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  6. Content type: Research

    Osteoporosis is a major public health problem with low bone mass affecting nearly half the women aged 50 years or older. Evidence from various studies has shown that higher body mass index (BMI) is a protectiv...

    Authors: Jonathan P Castro, Linda A Joseph, John J Shin, Surender K Arora, John Nicasio, Joshua Shatzkes, Irina Raklyar, Irina Erlikh, Vincent Pantone, Gul Bahtiyar, Leon Chandler, Lina Pabon, Sara Choudhry, Nilofar Ghadiri, Pramodini Gosukonda, Rangnath Muniyappa…

    Citation: Nutrition & Metabolism 2005 2:9

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  7. Content type: Research

    Cholesterol ester transfer protein (CETP) plays a major role in regulating the levels of LDL- and HDL-cholesterol. We previously observed a fish-oil-induced elevation of low-density lipoprotein (LDL)-and very-...

    Authors: Pujitha P de Silva, Alka Agarwal-Mawal, Phillip J Davis and Sukhinder Kaur Cheema

    Citation: Nutrition & Metabolism 2005 2:8

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  8. Content type: Brief communication

    Although feeding deficits have been reported in snakes and lizards following vomeronasal system disruption, no deficit has been previously reported in a mammal. We tested gray short-tailed opossums with items ...

    Authors: Mimi Halpern, Yasmine Daniels and Ido Zuri

    Citation: Nutrition & Metabolism 2005 2:6

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  9. Content type: Review

    Obesity and type 2 diabetes are occurring at epidemic rates in the United States and many parts of the world. The "obesity epidemic" appears to have emerged largely from changes in our diet and reduced physica...

    Authors: Heather Basciano, Lisa Federico and Khosrow Adeli

    Citation: Nutrition & Metabolism 2005 2:5

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  10. Content type: Commentary

    Ancel Keys, Ph.D., who died in November, 2004, at the age of 100, was among the first scientists to recognize that human atherosclerosis is not an inevitable consequence of aging, and that a high-fat diet can ...

    Authors: Theodore B VanItallie

    Citation: Nutrition & Metabolism 2005 2:4

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  11. Content type: Research

    In 2001 the National Cholesterol Education Program (NCEP) provided a categorical definition for metabolic syndrome (c-MetS). We studied the extent to which two ethnic groups, Blacks and Whites were affected by...

    Authors: Aldi T Kraja, Steven C Hunt, James S Pankow, Richard H Myers, Gerardo Heiss, Cora E Lewis, DC Rao and Michael A Province

    Citation: Nutrition & Metabolism 2005 2:2

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  12. Content type: Research

    Phytoestrogens derived from soy foods (or isoflavones) have received prevalent usage due to their 'health benefits' of decreasing: a) age-related diseases, b) hormone-dependent cancers and c) postmenopausal sy...

    Authors: Edwin D Lephart, James P Porter, Trent D Lund, Lihong Bu, Kenneth DR Setchell, Gina Ramoz and William R Crowley

    Citation: Nutrition & Metabolism 2004 1:16

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  13. Content type: Review

    It is commonly held that "a calorie is a calorie", i.e. that diets of equal caloric content will result in identical weight change independent of macronutrient composition, and appeal is frequently made to the...

    Authors: Eugene J Fine and Richard D Feinman

    Citation: Nutrition & Metabolism 2004 1:15

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  14. Content type: Research

    To compare the effects of isocaloric, energy-restricted very low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss, body composition, trunk fat mass, and resting energy expenditure (REE) in o...

    Authors: JS Volek, MJ Sharman, AL Gómez, DA Judelson, MR Rubin, G Watson, B Sokmen, R Silvestre, DN French and WJ Kraemer

    Citation: Nutrition & Metabolism 2004 1:13

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  15. Content type: Review

    There are likely many scenarios and pathways that can lead to metabolic syndrome. This paper reviews mechanisms by which the accumulation of visceral adipose tissue (VAT) may contribute to the metabolic syndro...

    Authors: Eric S Freedland

    Citation: Nutrition & Metabolism 2004 1:12

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  16. Content type: Research

    The high fat, low carbohydrate ketogenic diet (KD) was developed as an alternative to fasting for seizure management. While the mechanisms by which fasting and the KD inhibit seizures remain speculative, alter...

    Authors: John G Mantis, Nicole A Centeno, Mariana T Todorova, Richard McGowan and Thomas N Seyfried

    Citation: Nutrition & Metabolism 2004 1:11

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  17. Content type: Review

    The topical role of uric acid and its relation to cardiovascular disease, renal disease, and hypertension is rapidly evolving. Its important role both historically and currently in the clinical clustering phen...

    Authors: Melvin R Hayden and Suresh C Tyagi

    Citation: Nutrition & Metabolism 2004 1:10

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  18. Content type: Brief communication

    Epidemiological studies suggest a non-monotonic effect of alcohol consumption on cardiovascular risk, while there is strong evidence concerning the involvement of homocysteine levels on thrombosis. The aim of ...

    Authors: Christos Pitsavos, Demosthenes B Panagiotakos, Meropi D Kontogianni, Christina Chrysohoou, Yannis Chloptsios, Antonis Zampelas, Antonia Trichopoulou and Christodoulos Stefanadis

    Citation: Nutrition & Metabolism 2004 1:9

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  19. Content type: Research

    Although the effects of resistant starch (RS) on postprandial glycemia and insulinemia have been extensively studied, little is known about the impact of RS on fat metabolism. This study examines the relations...

    Authors: Janine A Higgins, Dana R Higbee, William T Donahoo, Ian L Brown, Melanie L Bell and Daniel H Bessesen

    Citation: Nutrition & Metabolism 2004 1:8

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  20. Content type: Review

    Following a low carbohydrate diet, there is a shift towards more fat and less carbohydrate oxidation to provide energy to skeletal muscle, both at rest and during exercise. This review summarizes recent work o...

    Authors: Sandra J Peters and Paul J LeBlanc

    Citation: Nutrition & Metabolism 2004 1:7

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  21. Content type: Review

    Daily energy expenditure consists of three components: basal metabolic rate, diet-induced thermogenesis and the energy cost of physical activity. Here, data on diet-induced thermogenesis are reviewed in relati...

    Authors: Klaas R Westerterp

    Citation: Nutrition & Metabolism 2004 1:5

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  22. Content type: Research

    Insulin resistance induced by a high fat diet has been associated with alterations in lipid content and composition in skeletal muscle and adipose tissue. Administration of β3-adrenoceptor (β3-AR) agonists was...

    Authors: Christian Darimont, Marco Turini, Micheline Epitaux, Irène Zbinden, Myriam Richelle, Eulàlia Montell, Andreu Ferrer-Martinez and Katherine Macé

    Citation: Nutrition & Metabolism 2004 1:4

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  23. Content type: Review

    The role of amino acids as substrates for protein synthesis is well documented. However, a function for amino acids in modulating the signal transduction pathways that regulate mRNA translation has only recent...

    Authors: Scot R Kimball and Leonard S Jefferson

    Citation: Nutrition & Metabolism 2004 1:3

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  24. Content type: Review

    Impaired physical performance is a common but not obligate result of a low carbohydrate diet. Lessons from traditional Inuit culture indicate that time for adaptation, optimized sodium and potassium nutriture,...

    Authors: Stephen D Phinney

    Citation: Nutrition & Metabolism 2004 1:2

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  25. Content type: Editorial

    A new Open Access journal, Nutrition & Metabolism (N&M) will publish articles that integrate nutrition with biochemistry and molecular biology. The open access process is chosen to provide rapid and accessible di...

    Authors: Richard D Feinman and M Mahmood Hussain

    Citation: Nutrition & Metabolism 2004 1:1

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