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  1. Content type: Research

    South Asians were reported to have a higher liver fat content as compared to BMI-matched Caucasians. This study compared the increase in liver fat content in response to overfeeding with a high fat diet in Sou...

    Authors: Siti N. Wulan, Vera B. Schrauwen-Hinderling, Klaas R. Westerterp and Guy Plasqui

    Citation: Nutrition & Metabolism 2015 12:18

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  2. Content type: Review

    The ability of inorganic nitrate and nitrite to convert to nitric oxide (NO), and some of its properties e.g. regulation of glucose metabolism, vascular homeostasis, and insulin signaling pathway, have recentl...

    Authors: Zahra Bahadoran, Asghar Ghasemi, Parvin Mirmiran, Fereidoun Azizi and Farzad Hadaegh

    Citation: Nutrition & Metabolism 2015 12:16

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  3. Content type: Brief communication

    Cigarette smoking is associated with an increased risk of type 2 diabetes mellitus (T2DM). Smokers exhibit low circulating levels of total adiponectin (ADPN) and high-molecular-weight (HMW) ADPN multimers. Blo...

    Authors: Mingzhen Li, Chunjun Li, Yu Liu, Yan Chen, Xiangdong Wu, Demin Yu, Victoria P Werth, Kevin Jon Williams and Ming-Lin Liu

    Citation: Nutrition & Metabolism 2015 12:15

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  4. Content type: Research

    There is great interest in the relationship between polyunsaturated fatty acids and health. Yet, the combinatory effect of factors such as sex, ethnicity, genetic polymorphisms and hormonal contraceptives (HC)...

    Authors: Salma A Abdelmagid, Shannon E Clarke, Kaitlin Roke, Daiva E Nielsen, Alaa Badawi, Ahmed El-Sohemy, David M Mutch and David WL Ma

    Citation: Nutrition & Metabolism 2015 12:14

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  5. Content type: Research

    Riboflavin (RF) is essential for normal cellular metabolic activities. Human cells obtain RF from their surroundings via a carrier-mediated process that involves RF transporters -1, -2 & -3 (hRFVT -1, -2 & -3;...

    Authors: Veedamali S Subramanian, Rubina Kapadia, Abhisek Ghosal and Hamid M Said

    Citation: Nutrition & Metabolism 2015 12:13

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  6. Content type: Methodology

    Metabolic therapy using ketogenic diets (KD) is emerging as an alternative or complementary approach to the current standard of care for brain cancer management. This therapeutic strategy targets the aerobic f...

    Authors: Joshua J Meidenbauer, Purna Mukherjee and Thomas N Seyfried

    Citation: Nutrition & Metabolism 2015 12:12

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  7. Content type: Research

    Pharmacological stimulation of peroxisome proliferator-activated receptor-gamma (PPAR-γ) has been recognized as a molecular switch in alleviating myocardial injury through modulating oxidative, inflammatory an...

    Authors: Neha Rani, Saurabh Bharti, Jagriti Bhatia, Ameesha Tomar, T C Nag, Ruma Ray and Dharamvir Singh Arya

    Citation: Nutrition & Metabolism 2015 12:11

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  8. Content type: Research

    The hallmark of Type 2 diabetes (T2D) is hyperglycemia, although there are multiple other metabolic abnormalities that occur with T2D, including insulin resistance and dyslipidemia. To advance T2D prevention a...

    Authors: Amit Kumar, Joseph Shiloach, Michael J Betenbaugh and Emily J Gallagher

    Citation: Nutrition & Metabolism 2015 12:8

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  9. Content type: Research

    Dementia induced by β-amyloid accumulation impairs peripheral glucose homeostasis, but red pepper extract improves glucose homeostasis. We therefore evaluated whether long-term oral consumption of different re...

    Authors: Hye Jeong Yang, Dae Young Kwon, Min Jung Kim, Suna Kang, Na Rang Moon, James W Daily and Sunmin Park

    Citation: Nutrition & Metabolism 2015 12:9

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  10. Content type: Research

    Diet has a significant relationship with the risk of coronary heart disease (CHD). Traditionally the effect of diet on CHD was measured with the biomarker for low-density lipoprotein (LDL) cholesterol. However...

    Authors: Marc J Mathews, Leon Liebenberg and Edward H Mathews

    Citation: Nutrition & Metabolism 2015 12:6

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  11. Content type: Research

    n-3 long chain polyunsaturated fatty acid (n-3 LC PUFA) increases β-oxidation and limits lipid accumulation in adipocytes. The current study was conducted to determine whether their precursor alpha-linolenic a...

    Authors: Xihong Zhou, Weiche Wu, Jingqing Chen, Xinxia Wang and Yizhen Wang

    Citation: Nutrition & Metabolism 2015 12:10

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  12. Content type: Brief communication

    Apolipoprotein (apo)B is the structural apoprotein of intestinally- and liver- derived lipoproteins and plays an important role in the transport of triacylglycerol (TAG) and cholesterol. Previous studies have ...

    Authors: Karani Santhanakrishnan Vimaleswaran, Anne M Minihane, Yue Li, Rosalyn Gill, Julie A Lovegrove, Christine M Williams and Kim G Jackson

    Citation: Nutrition & Metabolism 2015 12:7

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  13. Content type: Research

    Accumulative evidence in the literature suggests alcohol consumption is a protective factor of the metabolic syndrome (MS). However, few studies investigated the relationship between alcohol consumption and co...

    Authors: Jing Xiao, Jian-Ping Huang, Guang-Fei Xu, De-Xi Chen, Gui-Yun Wu, Min Zhang, Yi Shen and Hui Cai

    Citation: Nutrition & Metabolism 2015 12:5

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  14. Content type: Review

    This comprehensive review critically evaluates whether supposed health benefits propounded upon human consumption of conjugated linoleic acids (CLAs) are clinically proven or not. With a general introduction o...

    Authors: Sailas Benjamin, Priji Prakasan, Sajith Sreedharan, Andre-Denis G Wright and Friedrich Spener

    Citation: Nutrition & Metabolism 2015 12:4

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  15. Content type: Research

    Considering the suggested link between vitamin D insufficiency and several chronic diseases, attention should be given to approaches for improving vitamin D status. Elderly subjects are regarded as a high-risk...

    Authors: Alexandra Jungert and Monika Neuhäuser-Berthold

    Citation: Nutrition & Metabolism 2015 12:2

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  16. Content type: Research

    Adverse metabolic changes associated with loss of ovarian function increase the risk of developing metabolic syndrome and non-alcoholic fatty liver disease (NAFLD) in postmenopausal women. Naringenin improves ...

    Authors: Jia-Yu Ke, Kara L Kliewer, Essam M Hamad, Rachel M Cole, Kimerly A Powell, Rebecca R Andridge, Shana R Straka, Lisa D Yee and Martha A Belury

    Citation: Nutrition & Metabolism 2015 12:1

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  17. Content type: Research

    The aim of the present study was to examine the effects of onion as functional ingredient on the oxidative status, lipoprotein levels (total cholesterol-TC, HDL-C, LDL-C), triacylglycerides (TAG) and vascular ...

    Authors: Diana González-Peña, Javier Angulo, Susana Vallejo, Clara Colina-Coca, Begoña de Ancos, Carlos F Sánchez-Ferrer, Concepción Peiró and Concepción Sánchez-Moreno

    Citation: Nutrition & Metabolism 2014 11:57

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  18. Content type: Research

    African-Americans have higher HDL, less visceral adipose tissue (VAT) and lower triglyceride (TG) and apoCIII concentrations than whites, despite being more insulin-resistant. We studied in African-American an...

    Authors: Liyun Wang, Frank M Sacks, Jeremy D Furtado, Madia Ricks, Amber B Courville and Anne E Sumner

    Citation: Nutrition & Metabolism 2014 11:56

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  19. Content type: Research

    Hyperhomocysteinemia (HHcy) is an independent risk factor for liver diseases, such as fatty liver and hepatic fibrosis. However, the mechanisms underlying this pro-oxidative effect of homocysteine (Hcy) in hep...

    Authors: Xiaoqin Luo, Lei Xiao, Haixia Yang, Ruijuan Zhang, Manli Jiang, Jiahua Ni, Ting Lei and Nanping Wang

    Citation: Nutrition & Metabolism 2014 11:55

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  20. Content type: Research

    Members of the ALDH1 protein family, known as retinal dehydrogenases (RALDH), produce retinoic acid (RA), a metabolite of vitamin A, and may also oxidize other lipid aldehydes. Of three related ALDH1 genes, AL...

    Authors: Kyoko Ito, Reza Zolfaghari, Lei Hao and A Catharine Ross

    Citation: Nutrition & Metabolism 2014 11:54

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  21. Content type: Review

    Tocotrienols, members of the vitamin E family, are natural compounds found in a number of vegetable oils, wheat germ, barley, and certain types of nuts and grains. Like tocopherols, tocotrienols are also of fo...

    Authors: Haseeb Ahsan, Amjid Ahad, Jahangir Iqbal and Waseem A Siddiqui

    Citation: Nutrition & Metabolism 2014 11:52

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  22. Content type: Research

    Protein energy malnutrition is commonly associated with immune dysfunctions and is a major factor in susceptibility to infectious diseases.

    Authors: Karina Corware, Vanessa Yardley, Christopher Mack, Steffen Schuster, Hafid Al-Hassi, Shanthi Herath, Philip Bergin, Manuel Modolell, Markus Munder, Ingrid Müller and Pascale Kropf

    Citation: Nutrition & Metabolism 2014 11:51

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  23. Content type: Research

    A number of different pathways to obesity with different metabolic outcomes are recognised. Prenatal undernutrition in rats leads to increased fat deposition in adulthood. However, the form of obesity is metab...

    Authors: Nichola Thompson, Korinna Huber, Mirijam Bedürftig, Kathrin Hansen, Jennifer Miles-Chan and Bernhard H Breier

    Citation: Nutrition & Metabolism 2014 11:50

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  24. Content type: Research

    Lysine supplementation may have a positive influence on the regulation of glucose metabolism but it has not been tested in the geriatric population. Objective: We evaluated the impact of acute lysine supplemen...

    Authors: Il-Young Kim, Rick H Williams, Scott E Schutzler, Cosby J Lasley, Donald L Bodenner, Robert R Wolfe and Robert H Coker

    Citation: Nutrition & Metabolism 2014 11:49

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  25. Content type: Research

    The association between smoking and total energy expenditure (TEE) is still controversial. We examined this association in a multi-country study where TEE was measured in a subset of participants by the doubly...

    Authors: Semira Gonseth, Lara Dugas, Barathi Viswanathan, Terrence Forrester, Vicki Lambert, Jacob Plange-Rhule, Ramon Durazo-Arvizu, Amy Luke, Dale A Schoeller and Pascal Bovet

    Citation: Nutrition & Metabolism 2014 11:48

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  26. Content type: Research

    The diminished ability of aged muscle to self-repair is a factor behind sarcopenia and contributes to muscle atrophy. Muscle repair depends on satellite cells whose pool size is diminished with aging. A reduct...

    Authors: Carla Domingues-Faria, Audrey Chanet, Jérôme Salles, Alexandre Berry, Christophe Giraudet, Véronique Patrac, Philippe Denis, Katia Bouton, Nicolas Goncalves-Mendes, Marie-Paule Vasson, Yves Boirie and Stéphane Walrand

    Citation: Nutrition & Metabolism 2014 11:47

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  27. Content type: Research

    The mammalian target of rapamycin (mTOR) pathway is the primary regulator of muscle protein synthesis. Metabolic syndrome (MetS) is characterized by central obesity and insulin resistance; little is known abou...

    Authors: Petra Gran, Amy E Larsen, Maxine Bonham, Aimee L Dordevic, Thusitha Rupasinghe, Claudio Silva, Amsha Nahid, Dedreia Tull, Andrew J Sinclair, Cameron J Mitchell and David Cameron-Smith

    Citation: Nutrition & Metabolism 2014 11:46

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  28. Content type: Research

    Previously, we reported that vitamin A-enriched diet (129 mg/kg diet) intake reduces the adiposity development in obese rats of WNIN/Ob strain. Here, we hypothesize that dose lesser than 129 mg of vitamin A/kg...

    Authors: Anamthathmakula Prashanth, Shanmugam M Jeyakumar, Lodhu Singotamu, Nemani Harishankar, Nappan V Giridharan and Ayyalasomayajula Vajreswari

    Citation: Nutrition & Metabolism 2014 11:45

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  29. Content type: Research

    Recent data suggest that an increased level of high-density lipoprotein cholesterol (HDL-C) is not causally protective against heart disease, shifting focus to other sub-phenotypes of HDL. Prior work on the ef...

    Authors: Daniel Seung Kim, Amber A Burt, Jane E Ranchalis, Leah E Jarvik, Jason F Eintracht, Clement E Furlong and Gail P Jarvik

    Citation: Nutrition & Metabolism 2014 11:44

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  30. Content type: Research

    Ingesting Yerba Maté (YM) has become widely popular for health promotion, obesity prevention and body weight reduction, primarily due its thermogenic effectiveness. However, the YM effects on fat metabolism du...

    Authors: Ahmad Alkhatib

    Citation: Nutrition & Metabolism 2014 11:42

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  31. Content type: Research

    Imidazoline I3 receptors (I-3R) can regulate insulin secretion in pancreatic β-cells. It has been indicated that allantoin ameliorates hyperglycemia by activating imidazoline I2 receptors (I-2R). Thus, the effect...

    Authors: Cheng-Chia Tsai, Li-Jen Chen, Ho-Shan Niu, Kun-Ming Chung, Juei-Tang Cheng and Kao-Chang Lin

    Citation: Nutrition & Metabolism 2014 11:41

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  32. Content type: Research

    Fasting is a rigorous type of dietary restriction that is associate with a number of health benefits. During fasting, ketone bodies significantly increase in blood and become major body fuels, thereby sparing ...

    Authors: Shigeru Nakamura, Ryuji Hisamura, Sachiko Shimoda, Izumi Shibuya and Kazuo Tsubota

    Citation: Nutrition & Metabolism 2014 11:40

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  33. Content type: Research

    Diet is an important component of type 2 diabetes therapy. Low adherence to current therapeutic diets points out to the need for alternative dietary approaches. This study evaluated the effect of a different d...

    Authors: Andreea Soare, Yeganeh M Khazrai, Rossella Del Toro, Elena Roncella, Lucia Fontana, Sara Fallucca, Silvia Angeletti, Valeria Formisano, Francesca Capata, Vladimir Ruiz, Carmen Porrata, Edlira Skrami, Rosaria Gesuita, Silvia Manfrini, Francesco Fallucca, Mario Pianesi…

    Citation: Nutrition & Metabolism 2014 11:39

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  34. Content type: Research

    Protein quality evaluation aims to determine the capacity of food sources and diets to meet protein and indispensable amino acid (IAA) requirements. This study determined whether nitrogen balance was affected ...

    Authors: Eveline A Martens, Sze-Yen Tan, Richard D Mattes and Margriet S Westerterp-Plantenga

    Citation: Nutrition & Metabolism 2014 11:38

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  35. Content type: Brief communication

    Lipase Maturation Factor 1 (LMF1) is an ER-chaperone involved in the post-translational maturation and catalytic activation of vascular lipases including lipoprotein lipase (LPL), hepatic lipase (HL) and endot...

    Authors: Nicole Ehrhardt, Candy Bedoya and Miklós Péterfy

    Citation: Nutrition & Metabolism 2014 11:37

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  36. Content type: Research

    Dietary fibre-induced satiety offers a physiological approach to body weight regulation, yet there is lack of scientific evidence. This experiment quantified food intake, body weight and body composition respo...

    Authors: Clare L Adam, Patricia A Williams, Matthew J Dalby, Karen Garden, Lynn M Thomson, Anthony J Richardson, Silvia W Gratz and Alexander W Ross

    Citation: Nutrition & Metabolism 2014 11:36

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  37. Content type: Research

    The exact mechanism of the protective role of Resveratrol (Res) in lipid metabolism and oxidative stress is not well elucidated. The present study aimed to investigate the potential benefits and possible mecha...

    Authors: Wei Zhu, Sifan Chen, Zilun Li, Xiaohong Zhao, Wenxue Li, Yanshuang Sun, Zili Zhang, Wenhua Ling and Xiang Feng

    Citation: Nutrition & Metabolism 2014 11:35

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  38. Content type: Research

    A moderate low-carbohydrate diet has been receiving attention in the dietary management of type 2 diabetes (T2DM). A fundamental issue has still to be addressed; how much carbohydrate delta-reduction (Δcarbohy...

    Authors: Hajime Haimoto, Tae Sasakabe, Takahiko Kawamura, Hiroyuki Umegaki, Masashi Komeda and Kenji Wakai

    Citation: Nutrition & Metabolism 2014 11:33

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  39. Content type: Research

    Obesity is a major risk factor for insulin resistance, type 2 diabetes, and stroke. Flavonoids are effective antioxidants that protect against these chronic diseases. In this study, we evaluated the effects of...

    Authors: Rie Tsutsumi, Tomomi Yoshida, Yoshitaka Nii, Naoki Okahisa, Shinya Iwata, Masao Tsukayama, Rei Hashimoto, Yasuko Taniguchi, Hiroshi Sakaue, Toshio Hosaka, Emi Shuto and Tohru Sakai

    Citation: Nutrition & Metabolism 2014 11:32

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  40. Content type: Review

    Prostate cancer is the second most common cause of cancer worldwide after lung cancer. There is increasing evidence that diet and lifestyle plays a crucial role in prostate cancer biology and tumourigenesis. P...

    Authors: Dalvinder Mandair, Roberta Elisa Rossi, Marinos Pericleous, Tara Whyand and Martyn Evan Caplin

    Citation: Nutrition & Metabolism 2014 11:30

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  41. Content type: Research

    The lipid messenger phosphatidic acid (PA) plays a critical role in the stimulation of mTOR signaling. However, the mechanism by which PA stimulates mTOR is currently unknown. Therefore, the purpose of this st...

    Authors: Jordan M Joy, David M Gundermann, Ryan P Lowery, Ralf Jäger, Sean A McCleary, Martin Purpura, Michael D Roberts, Stephanie MC Wilson, Troy A Hornberger and Jacob M Wilson

    Citation: Nutrition & Metabolism 2014 11:29

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  42. Content type: Research

    A high-fat diet promotes postprandial systemic inflammation and metabolic endotoxemia. We investigated the effects of three consecutive high-fat meals on endotoxemia, inflammation, vascular function, and postp...

    Authors: Mariann I Lassenius, Ville-Petteri Mäkinen, Christopher L Fogarty, Lina Peräneva, Matti Jauhiainen, Pirkko J Pussinen, Marja-Riitta Taskinen, Juha Kirveskari, Outi Vaarala, Janne K Nieminen, Sohvi Hörkkö, Antti J Kangas, Pasi Soininen, Mika Ala-Korpela, Daniel Gordin, Aila J Ahola…

    Citation: Nutrition & Metabolism 2014 11:28

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  43. Content type: Review

    Detrimental effects of acute and chronic alcohol (ethanol) consumption on human physiology are well documented in the literature. These adversely influence neural, metabolic, cardiovascular, and thermoregulato...

    Authors: Antonino Bianco, Ewan Thomas, Francesco Pomara, Garden Tabacchi, Bettina Karsten, Antonio Paoli and Antonio Palma

    Citation: Nutrition & Metabolism 2014 11:26

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    The Retraction Note to this article has been published in Nutrition & Metabolism 2014 11:43

  44. Content type: Research

    Obesity is associated with development of the cardiorenal metabolic syndrome, which is a constellation of risk factors, such as insulin resistance, inflammatory response, dyslipidemia, and high blood pressure ...

    Authors: Amanda Roberta de Almeida, Sarah Monte-Alegre, Michele Bianca Zanini, Aglécio Luiz Souza, Maurício Etchebehere and José Antonio Rocha Gontijo

    Citation: Nutrition & Metabolism 2014 11:25

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