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  1. Content type: Research

    Excessive production and/or reduced excretion of uric acid could lead to hyperuricemia, which could be a major cause of disability. Hyperuricemia has received increasing attention in the last few decades due t...

    Authors: Yu Wang, Zhijian Lin, Bing Zhang, Anzheng Nie and Meng Bian

    Citation: Nutrition & Metabolism 2017 14:38

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  2. Content type: Research

    Previous studies have shown that early life nutrition can modulate the development of white adipose tissue and thereby affect the risk on obesity and metabolic disease later in life. For instance, postnatal fe...

    Authors: Andrea Kodde, Eline M. van der Beek, Esther Phielix, Eefje Engels, Lidewij Schipper and Annemarie Oosting

    Citation: Nutrition & Metabolism 2017 14:37

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  3. Content type: Research

    Inflammation is associated with increased bone resorption; the role of inflammation in postprandial bone turnover has not been explored. Consumption of milk fat globule membrane (MFGM) reduces inflammation in ...

    Authors: Tara S. Rogers, Elieke Demmer, Nancy Rivera, Erik R. Gertz, J. Bruce German, Jennifer T. Smilowitz, Angela M. Zivkovic and Marta D. Van Loan

    Citation: Nutrition & Metabolism 2017 14:36

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  4. Content type: Research

    Amino acid availability stimulates protein synthesis via the mTORC1 (mechanistic target of rapamycin complex 1) signaling pathway. In response to an increase in cellular amino acid availability, translocation ...

    Authors: Ted G. Graber, Michael S. Borack, Paul T. Reidy, Elena Volpi and Blake B. Rasmussen

    Citation: Nutrition & Metabolism 2017 14:35

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    A Erratum has been published.

  5. Content type: Research

    Adipokines are a set of cytokines secreted by white adipose tissue that have been suggested to be involved in the development of cardiovascular diseases. We aimed to evaluate the cross-sectional associations o...

    Authors: Wenjin Liu, Lei Jiang, Jianping Chen, Chaoqing Gao, Jianmei Zhou, Jiajun Zhou, Youwei Bai, Hong Chu, Wei Fan, Liang Wang, Zhuxing Sun, Xiurong Li and Junwei Yang

    Citation: Nutrition & Metabolism 2017 14:34

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  6. Content type: Research

    No intervention follow-up study has examined the association between plasma n-6 polyunsaturated fatty acids (PUFAs) and lipoprotein-associated phospholipase A2 (Lp-PLA2), which is a risk factor for cardiovascular...

    Authors: Minkyung Kim, Minjoo Kim, Ayoung Lee, Hye Jin Yoo, Jung Soo Her, Sun Ha Jee and Jong Ho Lee

    Citation: Nutrition & Metabolism 2017 14:32

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  7. Content type: Research

    Saturated fatty acids have been shown to cause insulin resistance and low-grade chronic inflammation, whereas unsaturated fatty acids suppress inflammation via G-protein coupled receptor 120 (GPR120) in macrop...

    Authors: Hodaka Yamada, Tomio Umemoto, Masafumi Kakei, Shin-ichi Momomura, Masanobu Kawakami, San-e Ishikawa and Kazuo Hara

    Citation: Nutrition & Metabolism 2017 14:33

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  8. Content type: Research

    Ketosis can be induced in humans and in animals by fasting or dietary interventions, such as ketogenic diets. However, the increasing interest on the ketogenic state has motivated the development of alternativ...

    Authors: Rennan de Oliveira Caminhotto, Ayumi Cristina Medeiros Komino, Flaviane de Fatima Silva, Sandra Andreotti, Rogério Antônio Laurato Sertié, Gabriela Boltes Reis and Fabio Bessa Lima

    Citation: Nutrition & Metabolism 2017 14:31

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  9. Content type: Brief communication

    The elevated body weight in post-menopausal state attributes to the reduced estrogen levels which is alleviated by resveratrol (RES) but its role in control rats is not well understood. The main objective of t...

    Authors: Rupali Sharma, Neel Kamal Sharma and M. Thungapathra

    Citation: Nutrition & Metabolism 2017 14:30

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  10. Content type: Review

    Myostatin (MSTN), also referred to as growth and differentiation factor-8, is a protein secreted in muscle tissues. Researchers believe that its primary function is in negatively regulating muscle because a mu...

    Authors: Bing Deng, Feng Zhang, Jianghui Wen, Shengqiang Ye, Lixia Wang, Yu Yang, Ping Gong and Siwen Jiang

    Citation: Nutrition & Metabolism 2017 14:29

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  11. Content type: Research

    Real-time and dynamic assessment of an individual’s lipid homeostatic state in blood is complicated due to the need to collect samples in a clinical environment. In the context of precision medicine and popula...

    Authors: Fei Gao, Justice McDaniel, Emily Y. Chen, Hannah E. Rockwell, Jeremy Drolet, Vivek K. Vishnudas, Vladimir Tolstikov, Rangaprasad Sarangarajan, Niven R. Narain and Michael A. Kiebish

    Citation: Nutrition & Metabolism 2017 14:28

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  12. Content type: Research

    Obesity is a risk factor for increased cardiovascular disease. Whether vitamin D deficiency modifies this association is unclear. Here, we examined the association of obesity and vitamin D deficiency with vasc...

    Authors: Jwa-Kyung Kim, Mi Jin Park, Young Rim Song, Hyung Jik Kim and Sung Gyun Kim

    Citation: Nutrition & Metabolism 2017 14:27

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  13. Content type: Research

    Vitamin D insufficiency (serum 25-OH vitamin D > 10 ng/ml and < 30 ng/ml) is prevalent in the obese (body mass index (BMI) > 30 kg/m2), yet relationships between the two are poorly understood. Objectives of this ...

    Authors: Kenneth L. Seldeen, Manhui Pang, Maria Rodríguez-Gonzalez, Mireya Hernandez, Zachary Sheridan, Ping Yu and Bruce R. Troen

    Citation: Nutrition & Metabolism 2017 14:26

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  14. Content type: Research

    This study aimed to investigate the relationships among osteocalcin, leptin and metabolic health outcomes in children ages 9–13 years.

    Authors: Kelly Virecoulon Giudici, Joseph M. Kindler, Berdine R. Martin, Emma M. Laing, George P. McCabe, Linda D. McCabe, Dorothy B. Hausman, Lígia Araújo Martini, Richard D. Lewis, Connie M. Weaver, Munro Peacock and Kathleen M. Hill Gallant

    Citation: Nutrition & Metabolism 2017 14:25

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  15. Content type: Review

    The prevalence of type 2 diabetes (T2D) is rapidly increasing, and effective strategies to manage and prevent this disease are urgently needed. Resistance training (RT) promotes health benefits through increas...

    Authors: Dominik H. Pesta, Renata L. S. Goncalves, Anila K. Madiraju, Barbara Strasser and Lauren M. Sparks

    Citation: Nutrition & Metabolism 2017 14:24

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  16. Content type: Review

    Natural compounds capable of inducing apoptosis in cancer cells have always been of considerable interest as potential anti-cancer agents. Many such compounds are under screening and development with their pot...

    Authors: Ajaz A. Bhat, Kirti S. Prabhu, Shilpa Kuttikrishnan, Roopesh Krishnankutty, Jayaprakash Babu, Ramzi M. Mohammad and Shahab Uddin

    Citation: Nutrition & Metabolism 2017 14:23

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  17. Content type: Research

    Dietary salts are important factors in metabolic disorders. They are vital components of enzymes, vitamins, hormones, and signal transduction that act synergistically to regulate lipid metabolism. Our previous...

    Authors: Jun Ling, Christopher Brey, Megan Schilling, Farah Lateef, Zenaida P. Lopez-Dee, Kristopher Fernandes, Kavita Thiruchelvam, Yi Wang, Kshitij Chandel, Kai Rau, Ranjit Parhar, Futwan Al-Mohanna, Randy Gaugler and Sarwar Hashmi

    Citation: Nutrition & Metabolism 2017 14:22

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  18. Content type: Research

    The mother’s consumption of high-fat food can affect glucose metabolism and the hypothalamic–pituitary–adrenal axis responsiveness in the offspring and potentially affect the metabolic responses to stress as w...

    Authors: Roxana Karbaschi, Homeira Zardooz, Fariba Khodagholi, Leila Dargahi, Mina Salimi and FatemehSadat Rashidi

    Citation: Nutrition & Metabolism 2017 14:20

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  19. Content type: Methodology

    A shift from respiration to fermentation is a common metabolic hallmark of cancer cells. As a result, glucose and glutamine become the prime fuels for driving the dysregulated growth of tumors. The simultaneou...

    Authors: Thomas N. Seyfried, George Yu, Joseph C. Maroon and Dominic P. D’Agostino

    Citation: Nutrition & Metabolism 2017 14:19

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  20. Content type: Research

    The ketogenic diet (KD) is a very low-carbohydrate, high-fat and adequate-protein diet that without limiting calories induces different metabolic adaptations, eg, increased levels of circulating ketone bodies ...

    Authors: Paul Urbain, Lena Strom, Lena Morawski, Anja Wehrle, Peter Deibert and Hartmut Bertz

    Citation: Nutrition & Metabolism 2017 14:17

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  21. Content type: Research

    Nutritional status in early life is critically involved in the metabolic phenotype of offspring. However the changes triggered by maternal consumption of high-fat diet (HFD) in pre- or postnatal period should ...

    Authors: Laís Angélica de Paula Simino, Thaís de Fante, Marina Figueiredo Fontana, Fernanda Oliveira Borges, Márcio Alberto Torsoni, Marciane Milanski, Lício Augusto Velloso and Adriana Souza Torsoni

    Citation: Nutrition & Metabolism 2017 14:16

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  22. Content type: Research

    Non-nutritive sweeteners (NNS) have been associated with increased prevalence of obesity. In previous studies, we demonstrated that saccharin could induce an increase in weight gain either when compared to suc...

    Authors: Denise Entrudo Pinto, Kelly Carraro Foletto, Ramiro Barcos Nunes, Pedro Dal Lago and Marcello Casaccia Bertoluci

    Citation: Nutrition & Metabolism 2017 14:18

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  23. Content type: Brief communication

    Western diet containing both saturated fat and cholesterol impairs cardio-metabolic health partly by modulating diversity and function of the microbiota. While diet containing only high fat has comparable effe...

    Authors: Lidiya G. Dimova, Nikola Zlatkov, Henkjan J. Verkade, Bernt Eric Uhlin and Uwe J. F. Tietge

    Citation: Nutrition & Metabolism 2017 14:15

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  24. Content type: Research

    Orlistat is a lipase inhibitor which reduced absorption of dietary fat by ~30% thereby inducing a weight loss; however, side effects occur as a consequence of increased colonic fat content. To test the hypothe...

    Authors: Mette Kristensen, Signe Rømer Juul, Karina Vejrum Sørensen, Janne Kunchel Lorenzen and Arne Astrup

    Citation: Nutrition & Metabolism 2017 14:13

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  25. Content type: Review

    The mechanistic target of rapamycin complex 1 (mTORC1) has received much attention in the field of exercise physiology as a master regulator of skeletal muscle hypertrophy. The multiprotein complex is regulate...

    Authors: Peter Bond

    Citation: Nutrition & Metabolism 2017 14:12

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  26. Content type: Research

    The prevalence of type 2 diabetes is increasing in worldwide despite the development of new treatment methods. Aim of the study was to evaluate a weight loss method on body composition, glycemic, lipid and hor...

    Authors: Kuat Oshakbayev, Bibazhar Dukenbayeva, Gulnar Togizbayeva, Aigul Durmanova, Meruyert Gazaliyeva, Abdul Sabir, Aliya Issa and Alisher Idrisov

    Citation: Nutrition & Metabolism 2017 14:11

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  27. Content type: Research

    The milk fat globule membrane (MFGM) is primarily composed of polar phospho- and sphingolipids, which have established biological effects on neuroplasticity. The present study aimed to investigate the effect o...

    Authors: James F. Markworth, Brenan Durainayagam, Vandre C. Figueiredo, Karen Liu, Jian Guan, Alastair K. H. MacGibbon, Bertram Y. Fong, Aaron C. Fanning, Angela Rowan, Paul McJarrow and David Cameron-Smith

    Citation: Nutrition & Metabolism 2017 14:9

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  28. Content type: Research

    Single nucleotide polymorphisms (SNPs) in lipoprotein lipase gene (LPL) have been shown to influence metabolism related to lipid phenotypes. Dietary factors have been shown to modify the association between LPL S...

    Authors: K. A. Ayyappa, I. Shatwan, D. Bodhini, L. R. Bramwell, K. Ramya, V. Sudha, R. M. Anjana, J. A. Lovegrove, V. Mohan, V. Radha and K. S. Vimaleswaran

    Citation: Nutrition & Metabolism 2017 14:8

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  29. Content type: Research

    Progressive decline in skeletal muscle mass and function are growing concerns in an aging population. Diet and physical activity are important for muscle maintenance but these requirements are not always met. ...

    Authors: Malkanthi Evans, Najla Guthrie, John Pezzullo, Toran Sanli, Roger A. Fielding and Aouatef Bellamine

    Citation: Nutrition & Metabolism 2017 14:7

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  30. Content type: Research

    The AGE-RAGE-oxidative stress (AROS) axis is involved in the onset and progression of metabolic syndrome induced by a high-fructose diet (HFD). PPARγ activation is known to modulate metabolic syndrome; however...

    Authors: Luca Cannizzaro, Giuseppe Rossoni, Federica Savi, Alessandra Altomare, Cristina Marinello, Thammakorn Saethang, Marina Carini, D. Michael Payne, Trairak Pisitkun, Giancarlo Aldini and Asada Leelahavanichkul

    Citation: Nutrition & Metabolism 2017 14:5

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  31. Content type: Research

    Type 2 diabetes is associated with greater relative risk of cardiovascular diseases in women than in men, which is not well understood. Consequently, we have investigated if male and female displayed differenc...

    Authors: Martine Desrois, Carole Lan, Jamileh Movassat and Monique Bernard

    Citation: Nutrition & Metabolism 2017 14:6

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  32. Content type: Research

    Dietary thylakoids derived from spinach have beneficial effects on body fat accumulation and blood lipids as demonstrated in humans and rodents. Important mechanisms established include delayed fat digestion i...

    Authors: Karin G. Stenkula, Eva-Lena Stenblom, Caroline Montelius, Emil Egecioglu and Charlotte Erlanson-Albertsson

    Citation: Nutrition & Metabolism 2017 14:4

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  33. Content type: Research

    Fasting is the most widely prescribed and self-imposed strategy for treating excessive weight gain and obesity, and has been shown to exert a number of beneficial effects. The aim of the present study was to d...

    Authors: Hao-Neng Tang, Chen-Yi Tang, Xiao-Fei Man, Shu-Wen Tan, Yue Guo, Jun Tang, Ci-La Zhou and Hou-De Zhou

    Citation: Nutrition & Metabolism 2017 14:3

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  34. Content type: Research

    Although the effects of probiotics on the immune system have been extensively evaluated under disease states, their role in healthy situations remains unclear, since changes are hardly expected under immunolog...

    Authors: Noemí Redondo, Esther Nova, Alina Gheorghe, Ligia Esperanza Díaz, Aurora Hernández and Ascensión Marcos

    Citation: Nutrition & Metabolism 2017 14:2

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    The Erratum to this article has been published in Nutrition & Metabolism 2017 14:40

  35. Content type: Review

    In recent years, there has been growing concern about the occurrence of metabolic syndrome (MetS) at an early age and its effects on bone mass in adolescents. Adolescence is considered a critical period for bo...

    Authors: Valéria Nóbrega da Silva, Luciana Nunes Mosca Fiorelli, Carla Cristiane da Silva, Cilmery Suemi Kurokawa and Tamara Beres Lederer Goldberg

    Citation: Nutrition & Metabolism 2017 14:1

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  36. Content type: Review

    The positive influences of glucagon-like peptide-1 (GLP-1) on blood glucose homeostasis, appetite sensations, and food intake provide a strong rationale for its therapeutic potential in the nutritional managem...

    Authors: Alexandra M. Bodnaruc, Denis Prud’homme, Rosanne Blanchet and Isabelle Giroux

    Citation: Nutrition & Metabolism 2016 13:92

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  37. Content type: Research

    OxyElite Pro (OEP) is a dietary supplement to increase metabolism which contains as key stimulant the ingredient 1,3-dimethylamylamine (DMAA). Serious adverse effects have been reported after OEP consumption h...

    Authors: Paulo Vinicios Camuzi Zovico, Victor Magalhães Curty, Marcos André Soares Leal, Eduardo Frizzera Meira, Daniel Ventura Dias, Lívia Carla de Melo Rodrigues, Silvana dos Santos Meyrelles, Edilamar Menezes De Oliveira, Paula Frizera Vassallo and Valério Garrone Barauna

    Citation: Nutrition & Metabolism 2016 13:90

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  38. Content type: Research

    Overweight and obesity are widespread chronic disorders defined as excessive fat accumulation, and are major risk factors for several chronic diseases including type 2 diabetes, coronary heart disease, high bl...

    Authors: Michele Cavalera, Ulrika Axling, Karin Berger and Cecilia Holm

    Citation: Nutrition & Metabolism 2016 13:91

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  39. Content type: Review

    Obesity and its associated metabolic syndrome continue to be a health epidemic in westernized societies and is catching up in the developing world. Despite such increases, little headway has been made to rever...

    Authors: Yusra Azhar, Ashish Parmar, Colette N. Miller, Janaiya S. Samuels and Srujana Rayalam

    Citation: Nutrition & Metabolism 2016 13:89

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  40. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD) is caused by multiple factors including hepatic oxidative stress, lipotoxicity, and mitochondrial dysfunction. Obesity is among the risk factors for NAFLD alongside ty...

    Authors: Shin-Yu Tsai, Pei-Chin Chung, Eddy E. Owaga, I-Jong Tsai, Pei-Yuan Wang, Jeng-I Tsai, Tien-Shun Yeh and Rong-Hong Hsieh

    Citation: Nutrition & Metabolism 2016 13:88

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  41. Content type: Research

    Obesity is still considered a risk factor for cardiovascular disease, although more recent knowledge also suggests obesity to be associated with reduced morbidity and mortality - the “obesity paradox”. This st...

    Authors: F. Edland, A. Wergeland, R. Kopperud, K. S. Åsrud, E. A. Hoivik, S. L. Witsø, R. Æsøy, L. Madsen, K. Kristiansen, M. Bakke, S. O. Døskeland and A. K. Jonassen

    Citation: Nutrition & Metabolism 2016 13:87

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  42. Content type: Research

    It is becoming increasingly evident that platelet chemokines are involved in distinct aspects of atherosclerosis. The aim of this study was to examine the effects of long-term supplementation with purified ant...

    Authors: Xiandan Zhang, Yanna Zhu, Fenglin Song, Yanling Yao, Fuli Ya, Dan Li, Wenhua Ling and Yan Yang

    Citation: Nutrition & Metabolism 2016 13:86

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  43. Content type: Research

    When indirect calorimetry is not available, predictive equations are used to estimate resing energy expenditure (REE). There is no consensus about which equation to use in hospitalized patients. The objective ...

    Authors: Hinke M. Kruizenga, Geesje H. Hofsteenge and Peter J.M. Weijs

    Citation: Nutrition & Metabolism 2016 13:85

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  44. Content type: Research

    Specific bio-active dietary compounds modulate numerous metabolic processes in adipose tissue (AT), including pre-adipocyte proliferation and differentiation. AT dysfunction, rather than an increased fat mass per...

    Authors: Ines Warnke, Johan W. E. Jocken, Rotraut Schoop, Christine Toepfer, Regina Goralczyk and Joseph Schwager

    Citation: Nutrition & Metabolism 2016 13:84

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  45. Content type: Erratum

    Authors: Amal Ahmed Mohamed, Maha Abdel Ghany, Gehan Lotfy Abdel Hakeem, Aya Mostafa, Rania Abdelmonem Khattab, Asmaa Mahmoud Abdalla, Laila El Morsi Abou El Fotoh, Abdel Azeem El Mazary, Madiha Abdalla Sayed and Ashraf Mohamed Abdel Fadil

    Citation: Nutrition & Metabolism 2016 13:83

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    The original article was published in Nutrition & Metabolism 2016 13:53

  46. Content type: Research

    Caffeine intake is generally estimated by self-reported consumption, but it remains unclear how well self-report associates with metabolite urinary excretion. We investigated the associations of self-reported ...

    Authors: Dusan Petrovic, Sandrine Estoppey Younes, Menno Pruijm, Belén Ponte, Daniel Ackermann, Georg Ehret, Nicolas Ansermot, Markus Mohaupt, Fred Paccaud, Bruno Vogt, Antoinette Pechère-Bertschi, Pierre-Yves Martin, Michel Burnier, Chin B. Eap, Murielle Bochud and Idris Guessous

    Citation: Nutrition & Metabolism 2016 13:81

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  47. Content type: Research

    Higher fibre intakes are associated with risk reduction for chronic diseases. However, many people find difficulty in consuming sufficient fibre through their diet. Supplements may be an effective alternative....

    Authors: Sebely Pal, Suleen Ho, Roland J. Gahler and Simon Wood

    Citation: Nutrition & Metabolism 2016 13:82

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