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  1. Content type: Research

    γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the central nervous system and reported to maintain the redox homeostasis and insulin secretion function of pancreatic β cells. This study t...

    Authors: Xue Tang, Renqiang Yu, Qin Zhou, Shanyu Jiang and Guowei Le

    Citation: Nutrition & Metabolism 2018 15:60

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  2. Content type: Research

    Previous studies have revealed the inductive effect of branched-chain amino acids (BCAAs) catabolism on fatty acid oxidation and metabolism, especially in muscle cells. In the present investigation, we have at...

    Authors: Navid Abedpoor, Farzaneh Taghian, Kamran Ghaedi, Iman Niktab, Zahra Safaeinejad, Farzaneh Rabiee, Sommayeh Tanhaei and Mohammad Hossein Nasr-Esfahani

    Citation: Nutrition & Metabolism 2018 15:59

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  3. Content type: Research

    Individuals’ peak bone mineral density (BMD) achieved and maintained at ages 20–40 years is the most powerful predictor of low bone mass and osteoporotic fractures later in life. The aim of this study was to i...

    Authors: Qi Zhao, Hui Shen, Kuan-Jui Su, Ji-Gang Zhang, Qing Tian, Lan-Juan Zhao, Chuan Qiu, Qiang Zhang, Timothy J. Garrett, Jiawang Liu and Hong-Wen Deng

    Citation: Nutrition & Metabolism 2018 15:57

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  4. Content type: Research

    The effects of vitamin D on the immune function of laying hens are not well understood. This study investigated the effects of vitamin D3 (VD3) on laying performance and immunological functions in laying hens und...

    Authors: Yanqiang Geng, Qiugang Ma, Zhong Wang and Yuming Guo

    Citation: Nutrition & Metabolism 2018 15:58

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  5. Content type: Research

    The aim in this study was to investigate the effect of vitamin D (25(OH)D3) supplementation on heat shock protein 60 (HSP 60) and other inflammatory markers (IL-17, TNF-α, PAB) in patients with coronary heart dis...

    Authors: Leila Sadat Bahrami, Seyed Hashem Sezavar Seyedi Jandaghi, Leila Janani, Mina Pahlavan, Seyed Mostafa Arabi, Homa Sadeghi and Mohammadreza Vafa

    Citation: Nutrition & Metabolism 2018 15:56

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  6. Content type: Research

    Reducing caloric intake is a proven intervention for mitigating and modulating morbidities associated with overnutrition. Caloric restriction is difficult to affect clinically, therefore, dietary interventions...

    Authors: Julie K. Bray, Gabriel S. Chiu, Leslie K. McNeil, Morgan L. Moon, Robyn Wall, Albert E. Towers and Gregory G. Freund

    Citation: Nutrition & Metabolism 2018 15:55

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  7. Content type: Research

    Very low carbohydrate (VLC) diets are used to promote weight loss and improve insulin resistance (IR) in obesity. Since the high fat content of VLC diets may predispose to hepatic steatosis and hepatic insulin...

    Authors: Kathleen V. Axen, Marianna A. Harper, Yu Fu Kuo and Kenneth Axen

    Citation: Nutrition & Metabolism 2018 15:54

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  8. Content type: Research

    Consumption of added sugars has been considered a worldwide public health concern by its association with metabolic syndrome and its comorbidities. Meanwhile, current studies have suggested high-protein diets ...

    Authors: Rosângela Maria Lopes Sousa, Nathalee Liberal Xavier Ribeiro, Bruno Araújo Serra Pinto, Jonas Rodrigues Sanches, Mariana Uchôa da Silva, Caio Fernando Ferreira Coêlho, Lucas Martins França, José Albuquerque de Figueiredo Neto and Antonio Marcus de Andrade Paes

    Citation: Nutrition & Metabolism 2018 15:53

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  9. Content type: Research

    Previous intervention studies have reported the association of the PPARG2 Pro12Ala (rs1801282) and IL6 -174G > C (rs1800795) polymorphisms with weight loss; however, their results are inconsistent. We aimed to in...

    Authors: Ana Paula Santos Rodrigues, Lorena Pereira Souza Rosa and Erika Aparecida Silveira

    Citation: Nutrition & Metabolism 2018 15:52

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  10. Content type: Research

    Obesity and comorbidities such as non-alcoholic fatty liver disease (NAFLD) are major public health burdens. Alterations in lipid metabolism are involved in hepatic diseases. The objective of this study was to...

    Authors: Irene Cantero, Itziar Abete, Josep Maria del Bas, Antoni Caimari, Lluís Arola, M. Angeles Zulet and J. Alfredo Martinez

    Citation: Nutrition & Metabolism 2018 15:51

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  11. Content type: Research

    Excess weight is a strong risk factor for the development of dysglycaemia. It has been suggested that changes in the metabolism microRNAs, small non-coding RNAs that regulate gene expression, could precede lat...

    Authors: Rafaella Cristhine Pordeus Luna, Mayara Karla dos Santos Nunes, Mussara Gomes Cavalcante Alves Monteiro, Cássia Surama Oliveira da Silva, Rayner Anderson Ferreira do Nascimento, Raquel Patrícia Ataíde Lima, Flávia Cristina Fernandes Pimenta, Naila Francis Paulo de Oliveira, Darlene Camati Persuhn, Aléssio Tony Cavalcanti de Almeida, Alcides da Silva Diniz, Cristina Wide Pissetti, Rodrigo Pinheiro Toledo Vianna, Flavia Emília Leite de Lima Ferreira, Maria da Conceição Rodrigues Gonçalves and Maria José de Carvalho Costa

    Citation: Nutrition & Metabolism 2018 15:49

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  12. Content type: Research

    To examine the impact of changes in all lipid measures including total cholesterol (TC), log-transformed triglycerides (Ln-TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol...

    Authors: Pegah Khaloo, Mitra Hasheminia, Maryam Tohidi, Hengameh Abdi, Mohammad Ali Mansournia, Fereidoun Azizi and Farzad Hadaegh

    Citation: Nutrition & Metabolism 2018 15:50

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  13. Content type: Research

    Obesity has been identified as a major risk factor for a large number of chronic diseases. Understanding factors related to adolescent obesity is critical for prevention of chronic diseases. The associations b...

    Authors: Hao Wang, Ruying Hu, Huaidong Du, Bragg Fiona, Jieming Zhong and Min Yu

    Citation: Nutrition & Metabolism 2018 15:48

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  14. Content type: Research

    Nut consumption has been shown to reduce the risk of cardiovascular disease. However, its role in the prevention of metabolic disorders, such as metabolic syndrome (Mets) and overweight/obesity, remains contro...

    Authors: Hang Li, Xia Li, Sheng Yuan, Yalei Jin and Jinping Lu

    Citation: Nutrition & Metabolism 2018 15:46

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  15. Content type: Research

    Until now, little research concerning the lipid-lowering and anti-obesity functions of garlic oil and onion oil has been performed. The objective of this study was to explore the effects of garlic oil and onio...

    Authors: Chao Yang, Lihua Li, Ligang Yang, Hui Lǚ, Shaokang Wang and Guiju Sun

    Citation: Nutrition & Metabolism 2018 15:43

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  16. Content type: Research

    Physical activity is associated with health in women. Published MET-values (MET: metabolic equivalent of task) may assess physical activity and energy expenditure but tend to be too low for subjects with a hig...

    Authors: Elisabet Forsum, Birgitta Janerot-Sjöberg and Marie Löf

    Citation: Nutrition & Metabolism 2018 15:45

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  17. Content type: Correction

    Following publication of the original article [1], the authors reported a typo in the article category.

    Authors: Arrigo F. G. Cicero, Federica Fogacci, Martina Rosticci, Angelo Parini, Marina Giovannini, Maddalena Veronesi, Sergio D’Addato and Claudio Borghi

    Citation: Nutrition & Metabolism 2018 15:44

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    The original article was published in Nutrition & Metabolism 2017 14:61

  18. Content type: Research

    Obesity alters adipose tissue metabolic and endocrine functioning, leading to an increased adiposity and release of pro-inflammatory cytokines. Various phytochemicals have been reported to contribute to the be...

    Authors: Janaiya S. Samuels, Rangaiah Shashidharamurthy and Srujana Rayalam

    Citation: Nutrition & Metabolism 2018 15:42

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  19. Content type: Research

    Many studies have been performed over time in order to determine the reliability of metabolic rate prediction equations.

    Authors: Eleni Pavlidou, Dimitris Petridis, Maria Tolia, Nikolaos Tsoukalas, Antigoni Poultsidi, Aristeidis Fasoulas, George Kyrgias and Constantinos Giaginis

    Citation: Nutrition & Metabolism 2018 15:41

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  20. Content type: Research

    Lactose synthesis rate is an important factor in milk production and quality in mammals. Understanding the lactose synthesis mechanism is crucial for the improvement of milk quantity and quality. However, rese...

    Authors: Yinzhi Zhang, Shihai Zhang, Wutai Guan, Fang Chen, Lin Cheng, Yantao Lv and Jun Chen

    Citation: Nutrition & Metabolism 2018 15:40

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  21. Content type: Research

    Maternal overnutrition including pre-pregnancy, pregnancy and lactation promotes a lipotoxic insult leading to metabolic dysfunction in offspring. Diet-induced obesity models (DIO) show that changes in hypotha...

    Authors: Robbi E. Cardenas-Perez, Lizeth Fuentes-Mera, Ana Laura de la Garza, Ivan Torre-Villalvazo, Luis A. Reyes-Castro, Humberto Rodriguez-Rocha, Aracely Garcia-Garcia, Juan Carlos Corona-Castillo, Armando R. Tovar, Elena Zambrano, Rocio Ortiz-Lopez, Jennifer Saville, Maria Fuller and Alberto Camacho

    Citation: Nutrition & Metabolism 2018 15:38

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  22. Content type: Research

    Bile acids play a pivotal role in cholesterol metabolism via the enterohepatic circulation. This study investigated the effects of medium-chain triglycerides (MCTs)/medium-chain fatty acids (MCFAs) on the redu...

    Authors: Huizi Li, Yinghua Liu, Xinsheng Zhang, Qing Xu, Yong Zhang, Changyong Xue and Changjiang Guo

    Citation: Nutrition & Metabolism 2018 15:37

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  23. Content type: Review

    This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to determine the effect of alpha-lipoic acid (ALA) supplementation on the inflammatory markers among patients with ...

    Authors: Maryam Akbari, Vahidreza Ostadmohammadi, Reza Tabrizi, Moein Mobini, Kamran B. Lankarani, Mahmood Moosazadeh, Seyed Taghi Heydari, Maryam Chamani, Fariba Kolahdooz and Zatollah Asemi

    Citation: Nutrition & Metabolism 2018 15:39

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  24. Content type: Research

    To compare the effects of baked flaxseed versus those who received a placebo on constipation symptom scores, weight, glycemic and lipid control in constipated patients with type 2 diabetes (T2D).

    Authors: Noureddin Soltanian and Mohsen Janghorbani

    Citation: Nutrition & Metabolism 2018 15:36

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  25. Content type: Research

    Long-chain n3-polyunsaturated fatty acids (LC n3-PUFA) are well known for their anti-inflammatory activity and their impact on cardiovascular disease. Cold-pressed whale oil (CWO) has half the amount of LC n3-...

    Authors: Mari Johannessen Walquist, Svein Kristian Stormo, Bjarne Østerud, Edel O. Elvevoll and Karl-Erik Eilertsen

    Citation: Nutrition & Metabolism 2018 15:35

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  26. Content type: Research

    The meta-analyses of genome-wide association studies identified several waist-hip ratio (WHR) related loci in individuals of European ancestry. Since the pattern of fat distribution and the relationship betwee...

    Authors: Qi-Ying Song, Xiang-Rui Meng, Anke Hinney, Jie-Yun Song, Tao Huang, Jun Ma and Hai-Jun Wang

    Citation: Nutrition & Metabolism 2018 15:34

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  27. Content type: Research

    Iron is a kind of essential trace mineral in the human body, while the studies on its physiological requirement are very limited recently, especially in China. And most studies were performed with the radioiso...

    Authors: Jie Cai, Tongxiang Ren, Yuhui Zhang, Zhilin Wang, Lingyan Gou, Zhengwu Huang, Jun Wang, Jianhua Piao, Xiaoguang Yang and Lichen Yang

    Citation: Nutrition & Metabolism 2018 15:29

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  28. Content type: Research

    Endothelial dysfunction underlies cardiovascular disease that frequently affects aged individuals. Characterized by local decrease in nitric oxide, it results from down-regulation of endothelial nitric oxide s...

    Authors: B. Rocha, A. R. Rodrigues, I. Tomada, M. J. Martins, J. T. Guimarães, A. M. Gouveia, H. Almeida and D. Neves

    Citation: Nutrition & Metabolism 2018 15:28

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  29. Content type: Research

    Little is known about the association of the protein phosphatase 1 regulatory subunit 3B gene (PPP1R3B) single nucleotide polymorphisms (SNPs) and serum lipid levels, the risk of coronary artery disease (CAD) and...

    Authors: Wei-Jun Li, Rui-Xing Yin, Jian-Hua Huang, Yuan Bin, Wu-Xian Chen and Xiao-Li Cao

    Citation: Nutrition & Metabolism 2018 15:27

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  30. Content type: Research

    Several studies have shown significant associations between manganese superoxide dismutase (MnSOD) Val16Ala polymorphism and diabetic complications, but this association has not been explored in relation with ...

    Authors: Mehrnaz Abbasi, Maryam S. Daneshpour, Mehdi Hedayati, Azadeh Mottaghi, Katayoun Pourvali and Fereidoun Azizi

    Citation: Nutrition & Metabolism 2018 15:25

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  31. Content type: Research

    Leukocyte activation (LA) testing identifies food items that induce a patient specific cellular response in the immune system, and has recently been shown in a randomized double blinded prospective study to re...

    Authors: Irma Garcia-Martinez, Theresa R. Weiss, Muhammad N. Yousaf, Ather Ali and Wajahat Z. Mehal

    Citation: Nutrition & Metabolism 2018 15:26

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  32. Content type: Research

    Obesity is associated with vitamin insufficiency and low grade inflammation. The purpose of this study was to investigate the effect of weight loss on folate, retinol, vitamin B12, D and E status and the degree o...

    Authors: Nina Rica Wium Geiker, Mette Veller, Louise Kjoelbaek, Jette Jakobsen, Christian Ritz, Anne Raben, Arne Astrup, Janne Kunchel Lorenzen, Lesli H. Larsen and Susanne Bügel

    Citation: Nutrition & Metabolism 2018 15:24

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  33. Content type: Correction

    Following publication of the original article [1] the authors noticed that the pie chart figure contains percentages (41%, 41%, 19%) that are slightly off given they don’t add to 100. They should instead read ...

    Authors: Michael A. Pellizzon and Matthew R. Ricci

    Citation: Nutrition & Metabolism 2018 15:23

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    The original article was published in Nutrition & Metabolism 2018 15:3

  34. Content type: Research

    Better choices of dietary lipid sources and substitution of refined by fortified oils could reduce the intake of saturated fatty acids (FA) and increase the intake of omega 3 FA concomitantly to healthy bioact...

    Authors: Frederic Capel, Alain Geloen, Carole Vaysse, Gaelle Pineau, Luc Demaison, Jean-Michel Chardigny, Marie-Caroline Michalski and Corinne Malpuech-Brugère

    Citation: Nutrition & Metabolism 2018 15:22

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  35. Content type: Correction

    Following publication of the original article [1] one of the authors wrote to say that his name had been spelt incorrectly as Ahmed Makki instead of Ahmad Makki.

    Authors: Shahida Khan, Ashraf Ali, Sarah Khan, Ahmed Bakillah, Ghazi Damanhouri, Aziz Khan, Ahmad Makki, Ibtehal AlAnsari and Naheed Banu

    Citation: Nutrition & Metabolism 2018 15:21

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    The original article was published in Nutrition & Metabolism 2018 15:13

  36. Content type: Research

    The objective of this study is to investigate the effects of a low-protein diet (LPD) starting from a young age on diabetic status and renal injury in a rat model of type 2 diabetes and obesity.

    Authors: Munehiro Kitada, Yoshio Ogura, Taeko Suzuki, Itaru Monno, Keizo Kanasaki, Ai Watanabe and Daisuke Koya

    Citation: Nutrition & Metabolism 2018 15:20

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  37. Content type: Research

    Considering the lack of data on the association between habitual dietary intakes of nitrate (NO3) and nitrite (NO2) and cardiovascular events, we assessed possible effects of dietary NO3 and NO2, in the conte...

    Authors: Zahra Bahadoran, Mattias Carlström, Asghar Ghasemi, Parvin Mirmiran, Fereidoun Azizi and Farzad Hadaegh

    Citation: Nutrition & Metabolism 2018 15:19

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  38. Content type: Research

    The resting metabolic rate (RMR) decrease, observed after an obesity reduction therapy is a determinant of a short-time weight regain. Thus, the objective of this study was to evaluate changes in RMR, and the ...

    Authors: Diego Gomez-Arbelaez, Ana B. Crujeiras, Ana I. Castro, Miguel A. Martinez-Olmos, Ana Canton, Lucia Ordoñez-Mayan, Ignacio Sajoux, Cristobal Galban, Diego Bellido and Felipe F. Casanueva

    Citation: Nutrition & Metabolism 2018 15:18

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  39. Content type: Research

    While the adverse metabolic effects of exposure to obesogenic diets during both the prenatal and early postnatal period are well established, the relative impact of exposure during these separate developmental...

    Authors: M. A. Vithayathil, J. R. Gugusheff, Z. Y. Ong, S. C. Langley-Evans, R. A. Gibson and B. S. Muhlhausler

    Citation: Nutrition & Metabolism 2018 15:17

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  40. Content type: Research

    Proper feeding practices during early childhood is fundamental for optimal child growth and development. However, scientific evidences on the determinants of dietary diversity are scanty. Particularly, the im...

    Authors: Gemechu Kumera, Endalkachew Tsedal and Mulatu Ayana

    Citation: Nutrition & Metabolism 2018 15:16

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  41. Content type: Research

    Obesity progressively leads to cardiac failure. Omega-3 polyunsaturated fatty acids (PUFA) have been shown to have cardio-protective effects in numerous pathological situations. It is not known whether rapesee...

    Authors: Thibault Leger, Isabelle Hininger-Favier, Frédéric Capel, Alain Geloen, Jean-Paul Rigaudière, Chrystèle Jouve, Elodie Pitois, Gaelle Pineau, Carole Vaysse, Jean-Michel Chardigny, Marie-Caroline Michalski, Corinne Malpuech-Brugère and Luc Demaison

    Citation: Nutrition & Metabolism 2018 15:15

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  42. Content type: Research

    Although alterations in the methionine metabolism cycle (MMC) have been associated with vascular complications of diabetes, there have not been consistent results about the levels of methionine and homocystein...

    Authors: Nayoung Han, Jung-woo Chae, Jihyun Jeon, Jaeyeon Lee, Hyun-moon Back, Byungjeong Song, Kwang-il Kwon, Sang Kyum Kim and Hwi-yeol Yun

    Citation: Nutrition & Metabolism 2018 15:14

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  43. Content type: Review

    Liver dysfunction is a topic of global concern with many advancing therapies being researched. Though vitamin D takes a center place, other therapies especially nutritional are also gaining ground. Vitamin D h...

    Authors: Shahida Khan, Ashraf Ali, Sarah Khan, Ahmed Bakillah, Ghazi Damanhouri, Aziz Khan, Ahmed Makki, Ibtehal AlAnsari and Naheed Banu

    Citation: Nutrition & Metabolism 2018 15:13

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    The Correction to this article has been published in Nutrition & Metabolism 2018 15:21

  44. Content type: Research

    Dietary bioactive compounds capable of improving metabolic profiles would be of great value, especially for overweight individuals undergoing a caloric restriction (CR) regimen. Curcumin (Cur), a possible anti...

    Authors: Taiki Miyazawa, Kiyotaka Nakagawa, Sharon H. Kim, Michael J. Thomas, Ligi Paul, Jean-Marc Zingg, Gregory G. Dolnikowski, Susan B. Roberts, Fumiko Kimura, Teruo Miyazawa, Angelo Azzi and Mohsen Meydani

    Citation: Nutrition & Metabolism 2018 15:12

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  45. Content type: Research

    Inhibition of Hsp90 has been shown to improve glucose tolerance and insulin sensitivity in mouse models of diabetes. In the present report, the specific isoform Hsp90ab1, was identified as playing a major role...

    Authors: Enxuan Jing, Pragalath Sundararajan, Ishita Deb Majumdar, Suwagmani Hazarika, Samantha Fowler, Angela Szeto, Stephane Gesta, Armando J. Mendez, Vivek K. Vishnudas, Rangaprasad Sarangarajan and Niven R. Narain

    Citation: Nutrition & Metabolism 2018 15:11

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